Talk:Mod:jgh001
Cpd dimers: Well written. Very good discussion. However, it would have been nice to view some jmols of your structures.
Taxol: Good to see you’re thinking in terms of obvious structural rearrangements rather than randomly moving atoms around. It would have been good to include both the breakdown of energies, rather than just showing the totals, and jmol structures of the other taxol configurations. Out of interest, could you find any further conformations of the 6-membered ring? What were the energies of those?
Carbene: Excellent discussion.
Glycosidation: Good answer but just missing the full picture. Why, perhaps in terms of a nucleophilic attack, would A be lower in energy than A’? What, in terms of boundaries, can molecules do under MOPAC that they cannot do under mechanics? Good effort though.
Mini-project: A shame you didn’t chose your own project. Another good introduction though. When presenting comparisons of data like this, you have to think of the best way to present it, rather than plonking it in a table. What we’re interested in here is the accuracy of your results, meaning the difference between yours and those in the literature. A further exploration of this would have been beneficial. Good to see you examining the H spectra.
Overall: Well written introductions and discussions. Overall, a very good effort.