Talk:Mod:gHoST wriTER

1.2.1 Cp dimers: Where are the jmols? A diagram would have helped in your discussion of thermo and kinetic control. Nice to see you’re taking the limitations of MM into account. Some quantitative data on bond angles would have been nice. Still, good discussion.

1.2.2 NAD: Looks good.

1.2.3 Taxol: Nice to see you’re looking in the lit (or at least googling things beyond the scope of the work). Your geometries and energies are fine, good work.

1.3.1 Carbene: Excellent discussion.

Mini-project: Wow, that is a brave choice of molecule. Which carbons were missing from the literature and can you think why this might be? Yes, optical rotation prediction relies heavily on a well predicted geometry, something I think will prove to be rather difficult with this molecule. NOE would help but the simplest technique to use would be 1H NMR. Not a bad project, especially considering the choice of molecule, but a more detailed statistical analysis of the deviation of your and the literature NMR spectra would have been nice.

Overall: Good discussion but a tad convoluted at points, a lot of what you said could be condensed (don’t worry, everyone does it), try to be more precise. Read it back to yourself and see if you could make it any more straightforward, assume the reader has your level of knowledge and above! It’s a shame you turned this in late, it was a good project.