Talk:Mod:GD409 module1

Cpd dimers: Your explanation of endo selectivity is a little meandering. Try to be more concise. Good to see you relating energies to structural features. And that you are aware of the limitations of MM2.

Taxol: The rotation is not around the carbonyl bond! Again, your answer is a little meandering.

Carbene: Well answered. However, look at your MOs. With a plane of symmetry in your molecule, would you not expect the MOs to be symmetrical as well?

Glycosidation: Is that the real reason you didn’t choose H? If you mention something earlier in your work you should say where. Good that you noticed similarities in MOPAC energies. Your discussion could have expanded on this a little. Particularly on why this is not true for MM2 (you mention only that the two methods use different parameters; what are these parameters and why should they give different answers?).

Mini-project: A shame you didn’t choose your own project. The sum of the differences between your calculated and the literature values will NOT tell you anything relevant about the accuracy of your calculations and will NOT tell you which isomer is preferred! This is a major flaw in your analysis! Very accurate optical rotation calculation; I’d say they are amazingly, rather than reasonably, close.

Overall: You seem to understand the questions, your answers are largely correct, but your English is letting you down. Really try to phrase things properly and concisely; shorten your sentences and try not to needlessly repeat yourself.