It:Eucalyptol
Appearance
Some Facts About Eucalyptol

- Eucalyptol is a cyclic ether, which is a natural organic compound.
- It is the main component of the essential oil of some eucalyptus species (up to 90%).
- It is a colourless liquid and has a fresh camphor-like aroma and a spicy, cooling taste.
- It can be found in bay leaves, mugwort, sweet basil, wormwood, rosemary, sage and other aromatic plant foliage.
- Fractional distillation of eucalyptus oil can produce large quantities of eucalyptol with a purity of 99.6-99.8%.
- It is insoluble in water but miscible with ether, ethanol and chloroform.

Structure of Eucalyptol
Eucalyptol | |
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Synonyms | 1,8-cineol, limonene oxide, cajeputol, 1,8-epoxy-p-menthane, 1,8-oxido-p-menthane, eucalyptol, eucalyptole, 1,3,3-trimethyl-2-oxabicyclo[2,2,2]octane, cineol, cineole. |
CAS No. | 470-82-6 |
Molecular formula | C10H18O |
Molecular Weight | 154.249 g/mol |
Melting Point | 1.5 °C ( 274.66 K) |
Boiling Point | 176 - 177 °C (449 - 450 K) |
Density | 0.9225 g/cm3 |
Refractive Index | 1.458 |
Smiles | CC12CCC(CC1)C(C)(C)O2 |
MSDS |
Eucalyptol | |||
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Synthesis of Eucalyptol
Uses of Eucalyptol
Due to it's plesant, spicy aroma and taste, eucalyptol is a frequent ingredient of the following products:
- flavourings
- fragrances
- cosmetics
- mouthwash
- cough suppressant
It is also used in aromatherapy and dentistry.
Medicinal Properties of Eucalyptol
- Evidence has shown that eucalyptol can reduce inflammation and pain.
- It is also capable of killing leukaemia cells.
- It relaxes bronchial and vascular smooth muscle and enhances blood circulation.
- Prolonged exposure to eucalyptol (inhalation) increases cerebral blood flow.
- It is used to treat bronchitis, sinusitis and chronic rhinitis as well as asthma.
- It helps to increase penetration of medicinal drugs.
- It reduces heart rate by a parasympathetic-dependent action and induces hypotension by a direct vasorelaxation.
- It can be used as a nasal decongestant and anticough agent
References
http://en.wikipedia.org/wiki/Eucalyptol
http://www.chemexper.com/ (type in eucalyptol)
http://webbook.nist.gov/cgi/cbook.cgi?Name=eucalyptol&Units=SI
http://en.wikipedia.org/wiki/Eucalyptus
M.C.M.S. Soares, C.E.N. Damiani, C.M. Moreira, I. Stefanon, D.V. Vassallo; Braz J Med Biol Res, March 2005, Volume 38(3) 453-461
Adams, J., Belley, M., Tetrahedron Letters, 27 (19), 2075-2078, 1986.