Scheme 22. Comparison of 13C NMR shifts for the computed taxol intermediate and those reported in literature (75MHz, C6D6). Carbon Atom Caluclated Shift (ppm) Literature Shift (ppm) Difference (ppm) 11 209.82 211.49 1.67 2 146.94 148.72 1.78 3 117.35 120.90 3.55 6 83.93 74.61 -9.32 5 62.82 60.53 -2.26 10 53.36 51.30 -2.06 13 51.75 50.94 -0.81 15 47.10 45.53 -1.57 16 42.81 43.28 0.47 17 41.04 40.82 -0.22 7 38.53 38.73 0.20 12 35.08 36.78 1.7 9 32.41 35.47 3.06 4 29.37 30.84 1.47 18 26.35 30.00 3.65 1 25.70 25.56 -0.14 19 23.15 25.35 2.2 14 22.05 22.21 0.16 20 20.68 21.39 0.71 8 18.85 19.83 0.98