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	<id>https://chemwiki.ch.ic.ac.uk/api.php?action=feedcontributions&amp;feedformat=atom&amp;user=Yyl206</id>
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	<updated>2026-04-24T12:03:50Z</updated>
	<subtitle>User contributions</subtitle>
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	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=13606</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=13606"/>
		<updated>2007-12-06T17:43:16Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]][http://www.sciencelab.com/xMSDS-Bisacodyl-9923092] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Storage&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
Store tablets in tightly closed containers in cool place.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available whereas the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
&lt;br /&gt;
4.[http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&amp;amp;DestParams=%3F%26CustomersID%3DResearchSoft%26CustomersIP%3D155.198.36.30%26Func%3DLinks%26PointOfEntry%3DFullRecord%26PublisherID%3DResearchSoft%26ServiceName%3DTransferToWos%26ServiceUser%3DLinks%26UT%3D000227833600015&amp;amp;DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html&amp;amp;SrcApp=EndNote&amp;amp;SrcAuth=ResearchSoft&amp;amp;Func=Frame&amp;amp;SID=2FN5k662jdILEb8f6od H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=13605</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=13605"/>
		<updated>2007-12-06T17:41:04Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Storage&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
Store tablets in tightly closed containers in cool place.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available whereas the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
&lt;br /&gt;
4.[http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&amp;amp;DestParams=%3F%26CustomersID%3DResearchSoft%26CustomersIP%3D155.198.36.30%26Func%3DLinks%26PointOfEntry%3DFullRecord%26PublisherID%3DResearchSoft%26ServiceName%3DTransferToWos%26ServiceUser%3DLinks%26UT%3D000227833600015&amp;amp;DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html&amp;amp;SrcApp=EndNote&amp;amp;SrcAuth=ResearchSoft&amp;amp;Func=Frame&amp;amp;SID=2FN5k662jdILEb8f6od H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10462</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10462"/>
		<updated>2007-10-31T17:28:14Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Syntheisis of Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available whereas the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
&lt;br /&gt;
4.[http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&amp;amp;DestParams=%3F%26CustomersID%3DResearchSoft%26CustomersIP%3D155.198.36.30%26Func%3DLinks%26PointOfEntry%3DFullRecord%26PublisherID%3DResearchSoft%26ServiceName%3DTransferToWos%26ServiceUser%3DLinks%26UT%3D000227833600015&amp;amp;DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html&amp;amp;SrcApp=EndNote&amp;amp;SrcAuth=ResearchSoft&amp;amp;Func=Frame&amp;amp;SID=2FN5k662jdILEb8f6od H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10461</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10461"/>
		<updated>2007-10-31T17:25:25Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available where as the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
&lt;br /&gt;
4.[http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&amp;amp;DestParams=%3F%26CustomersID%3DResearchSoft%26CustomersIP%3D155.198.36.30%26Func%3DLinks%26PointOfEntry%3DFullRecord%26PublisherID%3DResearchSoft%26ServiceName%3DTransferToWos%26ServiceUser%3DLinks%26UT%3D000227833600015&amp;amp;DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html&amp;amp;SrcApp=EndNote&amp;amp;SrcAuth=ResearchSoft&amp;amp;Func=Frame&amp;amp;SID=2FN5k662jdILEb8f6od H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10460</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10460"/>
		<updated>2007-10-31T17:24:28Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available where as the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
&lt;br /&gt;
4. [http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&amp;amp;DestParams=%3F%26CustomersID%3DResearchSoft%26CustomersIP%3D155.198.36.30%26Func%3DLinks%26PointOfEntry%3DFullRecord%26PublisherID%3DResearchSoft%26ServiceName%3DTransferToWos%26ServiceUser%3DLinks%26UT%3D000227833600015&amp;amp;DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html&amp;amp;SrcApp=EndNote&amp;amp;SrcAuth=ResearchSoft&amp;amp;Func=Frame&amp;amp;SID=2FN5k662jdILEb8f6od H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10459</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10459"/>
		<updated>2007-10-31T17:24:14Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available where as the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
4. [http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&amp;amp;DestParams=%3F%26CustomersID%3DResearchSoft%26CustomersIP%3D155.198.36.30%26Func%3DLinks%26PointOfEntry%3DFullRecord%26PublisherID%3DResearchSoft%26ServiceName%3DTransferToWos%26ServiceUser%3DLinks%26UT%3D000227833600015&amp;amp;DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html&amp;amp;SrcApp=EndNote&amp;amp;SrcAuth=ResearchSoft&amp;amp;Func=Frame&amp;amp;SID=2FN5k662jdILEb8f6od H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10458</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10458"/>
		<updated>2007-10-31T17:23:02Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available where as the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;br /&gt;
4. H. B. Mereyala and K. Sambaru, Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 2005, 44, 615-617.&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10457</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10457"/>
		<updated>2007-10-31T17:22:47Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* How it works */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Syntheisis of Bisacodyl ==&lt;br /&gt;
A new method of sythesise bisacodyl is introduced by Mereyala, H. B. and Sambaru, K. on 2005. The key step involves migrating the 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl[3] at 160 °C to yield the intermediate 4-hydroxyphenyl (2-pyridyl)ketone. The above reaction is then treated with phenol using H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;PO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; to give bisacodyl. This method has advantage over the existing literature methods because the starting material, pyridine-2-carboxylic acid is easily available where as the less stable compound, pyridine-2-carboxaldehyde was normally used previously.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10454</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10454"/>
		<updated>2007-10-31T17:12:35Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;font&amp;gt;&#039;&#039;&#039;Possible side effects&#039;&#039;&#039;&amp;lt;/font&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10449</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10449"/>
		<updated>2007-10-31T17:03:40Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* 3D Structure */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10448</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10448"/>
		<updated>2007-10-31T17:02:24Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* 3D Structure */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Bisacodyl in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Bisacodyl.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10447</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10447"/>
		<updated>2007-10-31T17:01:52Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are severe and persist.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10446</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10446"/>
		<updated>2007-10-31T16:59:11Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
&lt;br /&gt;
- stomach cramps &lt;br /&gt;
&lt;br /&gt;
- upset stomach &lt;br /&gt;
&lt;br /&gt;
- diarrhea &lt;br /&gt;
&lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
&lt;br /&gt;
- faintness &lt;br /&gt;
&lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
&lt;br /&gt;
Consult the doctor if the above symptoms are observed.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10445</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10445"/>
		<updated>2007-10-31T16:58:43Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
- stomach cramps &lt;br /&gt;
- upset stomach &lt;br /&gt;
- diarrhea &lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
- faintness &lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
Consult the doctor if the above symptoms are observed.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10444</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10444"/>
		<updated>2007-10-31T16:58:33Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
- stomach cramps &lt;br /&gt;
- upset stomach &lt;br /&gt;
- diarrhea &lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
- faintness &lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
Consult the doctor if the above symptoms are observed.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10443</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10443"/>
		<updated>2007-10-31T16:58:20Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
- stomach cramps &lt;br /&gt;
- upset stomach &lt;br /&gt;
- diarrhea &lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
- faintness &lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
Consult the doctor if the above symptoms are observed.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;br /&gt;
3.[http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601027.html]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10442</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10442"/>
		<updated>2007-10-31T16:57:53Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Side effects&#039;&#039;&#039;&lt;br /&gt;
The side effects of bisacodyl on human include:&lt;br /&gt;
- stomach cramps &lt;br /&gt;
- upset stomach &lt;br /&gt;
- diarrhea &lt;br /&gt;
- stomach and intestinal irritation &lt;br /&gt;
- faintness &lt;br /&gt;
- irritation or burning in the rectum (from suppositories)&lt;br /&gt;
Consult the doctor if the above symptoms are observed.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10441</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10441"/>
		<updated>2007-10-31T16:54:24Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* 3D Structure */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10440</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10440"/>
		<updated>2007-10-31T16:54:03Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* How it works */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10439</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10439"/>
		<updated>2007-10-31T16:53:45Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10438</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10438"/>
		<updated>2007-10-31T16:53:00Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== How it works ==&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10437</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10437"/>
		<updated>2007-10-31T16:52:23Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Storage_Temperature]&lt;br /&gt;
| 2-8°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10435</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10435"/>
		<updated>2007-10-31T16:32:38Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Introduction */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
Bisacodyl is a stimulant laxative, which is used in a short term basis to treat constipation. It acts on nerve endings in the walls of the intestine and the rectum. It causes the muscles in the intestine to contract more often and with increased force. When the intestine contracts it moves the gut contents along faster, thereby relieving constipation. It is also used to empty the bowel before surgery or examination procedures such as X-ray procedures using barium enemas. Bisacodyl is available with or without a medical prescription.&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10427</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10427"/>
		<updated>2007-10-31T15:24:59Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
== Introduction ==&lt;br /&gt;
&lt;br /&gt;
== 3D Structure ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10426</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10426"/>
		<updated>2007-10-31T15:13:39Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
1.[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
2.[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10425</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10425"/>
		<updated>2007-10-31T15:13:17Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;br /&gt;
[http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=* http://chembank.broad.harvard.edu/chemistry/viewMolecule.htm?cbid=982&amp;amp;desc=*]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10424</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10424"/>
		<updated>2007-10-31T15:12:34Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (pyridin-2-ylmethylene)di-4,1-phenylene diacetate  &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10423</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10423"/>
		<updated>2007-10-31T15:02:13Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| 407 K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10422</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10422"/>
		<updated>2007-10-31T14:58:24Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [https://www.ch.imperial.ac.uk/wiki/images/4/4f/Bisacodyl_Mass.gif MS]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Bisacodyl_Mass.gif&amp;diff=10421</id>
		<title>File:Bisacodyl Mass.gif</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Bisacodyl_Mass.gif&amp;diff=10421"/>
		<updated>2007-10-31T14:56:35Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10420</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10420"/>
		<updated>2007-10-31T14:56:24Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [https://www.ch.imperial.ac.uk/wiki/images/f/f0/Bisacodyl_IR.JPG IR], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Bisacodyl_IR.JPG&amp;diff=10418</id>
		<title>File:Bisacodyl IR.JPG</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Bisacodyl_IR.JPG&amp;diff=10418"/>
		<updated>2007-10-31T14:52:14Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10416</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10416"/>
		<updated>2007-10-31T14:47:51Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10415</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10415"/>
		<updated>2007-10-31T14:47:21Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| 4,4&#039;-Diacetoxydiphenylpyridyl-2-methane; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate; Phenol, 4,4&#039;-(2-pyridinylmethylene)bis-, diacetate (ester); Phenol, 4,4&#039;-(2-pyridylmethylene)di-, diacetate; Bicol; Bis(p-acetoxyphenyl)-2-pyridylmethane; 2-(4,4&#039;-Diacetoxydiphenylmethyl)pyridine; (4,4&#039;-Diacetoxydiphenyl)(2-pyridyl)methane; 4,4&#039;-Diacetoxydiphenylpyrid-2-ylmethane; Di-(p-acetoxyphenyl)-2-pyridylmethane; Di-(4-acetoxyphenyl)-2-pyridylmethane; Dulcolan; Dulcolax; Laxans; LA96A; Pyrilax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate; Sk-bisacodyl; Theralax; 4,4&#039;-(2-Pyridylmethylene)diphenol diacetate (ester); 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 603-50-9 &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
[http://webbook.nist.gov/cgi/cbook.cgi?Name=bisacodyl&amp;amp;Units=SI&amp;amp;cIR=on&amp;amp;cMS=on&amp;amp;cUV=on]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10412</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10412"/>
		<updated>2007-10-31T14:37:39Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| {{{OtherNames}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;22&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 361.19 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| {{{CASNo}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10409</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=10409"/>
		<updated>2007-10-31T14:32:59Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| {{{OtherNames}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| {{{Formula}}} &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CC(OC(C=C3)=CC=C3C(C2=CC=C(OC(C)=O)C=C2)C1=NC=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| {{{MolarMass}}}&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| {{{CASNo}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Bisacodyl&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;brown&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Bisacdoyl.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
 &lt;br /&gt;
 &lt;br /&gt;
    &amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
     &amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
   &amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
   &amp;lt;jmolButton&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
    &amp;lt;jmolAppletButton&amp;gt;&lt;br /&gt;
       &amp;lt;title&amp;gt;Show Pentahelicene in popup window&amp;lt;/title&amp;gt;&lt;br /&gt;
       &amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
       &amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
    &amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=9958</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=9958"/>
		<updated>2007-10-25T16:17:02Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Bisacodyl.jpg|200px|Bisacodyl]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] acetate &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| {{{OtherNames}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| {{{Formula}}} &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| {{{SMILES}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| {{{MolarMass}}}&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| {{{CASNo}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Bisacodyl.jpg&amp;diff=9954</id>
		<title>File:Bisacodyl.jpg</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Bisacodyl.jpg&amp;diff=9954"/>
		<updated>2007-10-25T16:13:06Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=9939</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=9939"/>
		<updated>2007-10-25T15:57:13Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Bisacodyl */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Bisacodyl ==&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:{{PAGENAME}}.jpg|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| {{{IUPACName}}}&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| {{{OtherNames}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| {{{Formula}}} &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| {{{SMILES}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| {{{MolarMass}}}&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| {{{CASNo}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=9938</id>
		<title>It07:Bisacodyl</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Bisacodyl&amp;diff=9938"/>
		<updated>2007-10-25T15:56:01Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: New page:  == Bisacodyl ==&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;br /&gt;
== Bisacodyl ==&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=9937</id>
		<title>It:projects</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=9937"/>
		<updated>2007-10-25T15:55:46Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* Supplemental  Project Page */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;__FORCETOC__&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;&#039;&#039;You MUST use the  Edit buttons on the right to edit this content.  Do NOT use the Edit button on the top of this page.&#039;&#039;&#039;&#039;&#039;&lt;br /&gt;
== Sandbox (Play-Pen) ==	 &lt;br /&gt;
		 &lt;br /&gt;
This is an area where you can play without worrying what you do. Enter it by pressing the [Edit] button &#039;&#039;&#039;on the right&#039;&#039;&#039; and &#039;&#039;&#039;not&#039;&#039;&#039; at the top. Go here for a [http://en.wikipedia.org/wiki/Wikipedia:Cheatsheet &#039;&#039;cheat sheet&#039;&#039;] summary of how to create a Wiki page.	 It&#039;s a free-for-all in here! Learn how to use a Wiki by coming here! PS This is how to do Greek:&amp;amp;alpha;, &amp;amp;beta; &amp;amp;Delta;, &amp;amp;delta;	 		 &lt;br /&gt;
Try copying/pasting some of the [http://www.ch.ic.ac.uk/local/it/lab1.html examples in the course work] into this page. See the effect by selecting &#039;&#039;&#039;Show Preview&#039;&#039;&#039;. Do not use &#039;&#039;&#039;Save Page&#039;&#039;&#039; so as to leave this area uncluttered for others.&lt;br /&gt;
----&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
|NEW: This demonstrates the use of  Jmol loading discrete molecule files (rather than having to paste them into the wiki page).  Upload the molecule file, and invoke it as shown here. Use it for eg loading large proteins etc.--[[User:Rzepa|Rzepa]] 16:07, 4 December 2006 (UTC) and --[[User:Rzepa|Rzepa]] 07:41, 16 October 2007 (BST) and  --[[User:Rzepa|Rzepa]] 15:56, 18 October 2007 (BST)&lt;br /&gt;
&lt;br /&gt;
If no rotatable molecule appears to the right, test that  [http://www.java.com/en/download/help/testvm.xml Java] is correctly functioning on your system.&lt;br /&gt;
&lt;br /&gt;
===References ===&lt;br /&gt;
This shows how citations&amp;lt;ref&amp;gt;Example of adding a citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; can be added to &lt;br /&gt;
text&amp;lt;ref&amp;gt;adding a further citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; to produce a nice effect.&lt;br /&gt;
&lt;br /&gt;
=== Collected citations appear below here ===&lt;br /&gt;
&amp;lt;references /&amp;gt;--[[User:Rzepa|Rzepa]] 15:18, 25 October 2007 (BST)&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;yellow&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
== Main Project Page ==&lt;br /&gt;
&#039;&#039;&#039;Please do not edit this page itself&#039;&#039;&#039;.  Click on one of the titles to start editing.&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
! bgcolor=&amp;quot;cyan&amp;quot; |Project&amp;lt;br /&amp;gt; Number&lt;br /&gt;
! bgcolor=&amp;quot;cyan&amp;quot; |General Keywords&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |01&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Lignocaine|Lignocaine (used in dentistry as a &amp;quot;local&amp;quot;)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |02&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Piperine|Piperine (active ingredient of both black and white pepper)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |03&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Rapamycin|Rapamycin (prevents transplant rejection)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |04&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Gossypol|Gossypol (male birth control)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |05&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Gentamycin|Gentamicin A (aminoglycoside antibiotic)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |06&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Herceptin|Herceptin (topical anticancer drug)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |07&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Gingerone|Zingerone (the characteristic smell of ginger)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |08&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Sucralose|Sucralose (non-metabolizable sweetening agent)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |09&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Bufotoxin|Bufotoxin (active component of the toad &#039;&#039;Bufo vulgaris&#039;&#039;)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |10&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Roaccutane|Roaccutane (treatment for severe acne)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |11&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Sibutramine|Sibutramine (appetite suppresor)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |12&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Anandamide|Anandamide (the &amp;quot;feel-good&amp;quot; factor in chocolate)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |13&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:h3nbh3|Ammonia-borane: H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;N-BH&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; (Hydrogen storage molecule?)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |14&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Methoxsalen|Methoxsalen (Treatment of psoriasis)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |15&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Hycocine|Hyoscine (From Mandrake and Witches Henbane, pre-med before surgery)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |16&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Capreomycin|Capreomycin (Drug-resistant TB)]]&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
== Supplemental  Project Page ==&lt;br /&gt;
&lt;br /&gt;
This area is for people who wish to create their own projects if none of the above appeal to them. Click on the  &#039;&#039;&#039;Edit&#039;&#039;&#039;  button to the right to open up an editable page,&lt;br /&gt;
then add an entry below as follows&lt;br /&gt;
&lt;br /&gt;
*&amp;lt;nowiki&amp;gt; [[it07:name_of_project|Descriptive name of intended project]]&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
*This will produce the effect:  [[it07:name_of_project|Descriptive name of intended project]]&lt;br /&gt;
----&lt;br /&gt;
#[[it07:sitagliptin_page|An example entry- in edit mode, please copy this line and paste below to add to this list]]&lt;br /&gt;
#[[it07:name_of_project|Vitamin C ]]&lt;br /&gt;
#[[it07:Cylcophosphamide|Cyclophosphamide]]&lt;br /&gt;
#[[it07:Terbutaline Sulphate|Terbutaline Sulphate]]&lt;br /&gt;
#[[it07:Caffeine|Caffeine]]&lt;br /&gt;
#[[it07:Mefloquine|Mefloquine]]&lt;br /&gt;
#[[it07:Cadaverine|Cadaverine]]&lt;br /&gt;
#[[it07:Cyanidin|Cyanidin]]&lt;br /&gt;
#[[it07:Ezetimibe|Ezetimibe]]&lt;br /&gt;
#[[it07:Azadirachtin|Azadirachtin]]&lt;br /&gt;
#[[it07:Nicotine|Nicotine]]&lt;br /&gt;
#[[Image:chem.png]][[it07:Cyclopentasiloxane|Cyclopentasiloxane]]&lt;br /&gt;
#[[it07:Trinitrotoluene|Trinitrotoluene]]&lt;br /&gt;
#[[it07:Hydroxychloroquine|Hydroxychloroquine]]&lt;br /&gt;
#[[Aspartame|Aspartame]]&lt;br /&gt;
#[[it07:Azulene|Azulene]]&lt;br /&gt;
#[[it07:Chlorine Trifluoride|Chlorine Trifluoride]]&lt;br /&gt;
#[[it07:Cholesterol|Cholesterol]]&lt;br /&gt;
#[[it07:Vitamin E|Vitamin E]]&lt;br /&gt;
#[[it07:Phenothiazine|Phenothiazine]]&lt;br /&gt;
#[[it07:linalool|linalool]]&lt;br /&gt;
#[[it07:Glutamic acid|Glutamic acid]]&lt;br /&gt;
#[[it07:N-(4-hydroxyphenyl)ethanamide|N-(4-hydroxyphenyl)ethanamide]]&lt;br /&gt;
#[[it07:Epinephrine|Epinephrine]]&lt;br /&gt;
#[[it07:Sodium Valproate|Sodium Valproate]]&lt;br /&gt;
#[[it07:Hyaluronic acid |Hyaluronic acid  ]]&lt;br /&gt;
#[[it07:Methylenedioxymethamphetamine |Methylenedioxymethamphetamine ]]&lt;br /&gt;
#[[it07:salicylic acid |salicylic acid ]]&lt;br /&gt;
#[[it07:Morphine|Morphine]]&lt;br /&gt;
#[[Cetirizine]]&lt;br /&gt;
#[[it07:Bisacodyl|Bisacodyl]]&lt;br /&gt;
&lt;br /&gt;
== Cetirizine ==&lt;br /&gt;
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== Wiki Templates ==&lt;br /&gt;
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[[Template:Chembox new]]&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=Cetirizine&amp;diff=9931</id>
		<title>Cetirizine</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=Cetirizine&amp;diff=9931"/>
		<updated>2007-10-25T15:41:53Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;=Cetirizine=&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Cetirizine&#039;&#039;&#039;, with the chemical name &#039;&#039;&#039;&#039;&#039;(±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid dihydrochloride&#039;&#039;&#039;&#039;&#039;,a major matabolite of Hydroxyzine,which is an orally active and selective H1-receptor antagonist. The chemical structure is shown below:&lt;br /&gt;
&lt;br /&gt;
[[Image:Cetirizine structure.gif]]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
This chemical compound is a white, crystalline powder and is water soluble, it is mainly used in medical treatment of allergies, hay fever, angioedema, and urticaria. ZYRTEC tablets(the active component of the chemical compound)are formulated as white, film-coated, rounded-off rectangular shaped tablets for oral administration and are available in 5 and 10 mg strengths.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid dihydrochloride&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C21H25ClN2O3 &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 461.82g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| White Crystalline powder, water soluble&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 83881-51-0&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Synonyms]&lt;br /&gt;
| Alatrol, Cetirizina MERCK, Cetzine Glaxo, Cetirizin, Humex, Letizen, Razene, Reactine, Zyrtec, Zirtec, Zodac, Zirtek, Zynor, Zyrlek&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Bioavailability]&lt;br /&gt;
| Well absorbed&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| 0.98 [[Debye|D]] at 25&amp;lt;sup&amp;gt;o&amp;lt;/sup&amp;gt;C tetrachloromethane solvent&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Cetirizine.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=Cetirizine&amp;diff=9928</id>
		<title>Cetirizine</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=Cetirizine&amp;diff=9928"/>
		<updated>2007-10-25T15:39:37Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;=Cetirizine=&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Cetirizine&#039;&#039;&#039;, with the chemical name &#039;&#039;&#039;&#039;&#039;(±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid dihydrochloride&#039;&#039;&#039;&#039;&#039;,a major matabolite of Hydroxyzine,which is an orally active and selective H1-receptor antagonist. The chemical structure is shown below:&lt;br /&gt;
&lt;br /&gt;
[[Image:Cetirizine structure.gif]]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
This chemical compound is a white, crystalline powder and is water soluble, it is mainly used in medical treatment of allergies, hay fever, angioedema, and urticaria. ZYRTEC tablets(the active component of the chemical compound)are formulated as white, film-coated, rounded-off rectangular shaped tablets for oral administration and are available in 5 and 10 mg strengths.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid dihydrochloride&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C21H25ClN2O3 &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 461.82g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| White Crystalline powder, water soluble&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 83881-51-0&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Synonyms]&lt;br /&gt;
| Alatrol, Cetirizina MERCK, Cetzine Glaxo, Cetirizin, Humex, Letizen, Razene, Reactine, Zyrtec, Zirtec, Zodac, Zirtek, Zynor, Zyrlek&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Bioavailability]&lt;br /&gt;
| Well absorbed&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| 0.98 [[Debye|D]] at 25&amp;lt;sup&amp;gt;o&amp;lt;/sup&amp;gt;C tetrachloromethane solvent&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;yellow&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Cetirizine.MOL&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=Cetirizine&amp;diff=9922</id>
		<title>Cetirizine</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=Cetirizine&amp;diff=9922"/>
		<updated>2007-10-25T15:35:27Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;=Cetirizine=&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Cetirizine&#039;&#039;&#039;, with the chemical name &#039;&#039;&#039;&#039;&#039;(±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid dihydrochloride&#039;&#039;&#039;&#039;&#039;,a major matabolite of Hydroxyzine,which is an orally active and selective H1-receptor antagonist. The chemical structure is shown below:&lt;br /&gt;
&lt;br /&gt;
[[Image:Cetirizine structure.gif]]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
This chemical compound is a white, crystalline powder and is water soluble, it is mainly used in medical treatment of allergies, hay fever, angioedema, and urticaria. ZYRTEC tablets(the active component of the chemical compound)are formulated as white, film-coated, rounded-off rectangular shaped tablets for oral administration and are available in 5 and 10 mg strengths.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| (±) - [2- [4- [ (4-chlorophenyl)phenylmethyl] -1- piperazinyl] ethoxy]acetic acid dihydrochloride&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C21H25ClN2O3 &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 461.82g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| White Crystalline powder, water soluble&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 83881-51-0&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Synonyms]&lt;br /&gt;
| Alatrol, Cetirizina MERCK, Cetzine Glaxo, Cetirizin, Humex, Letizen, Razene, Reactine, Zyrtec, Zirtec, Zodac, Zirtek, Zynor, Zyrlek&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Bioavailability]&lt;br /&gt;
| Well absorbed&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| 0.98 [[Debye|D]] at 25&amp;lt;sup&amp;gt;o&amp;lt;/sup&amp;gt;C tetrachloromethane solvent&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;yellow&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 80; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Cetirizine.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Cetirizine.MOL&amp;diff=9912</id>
		<title>File:Cetirizine.MOL</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Cetirizine.MOL&amp;diff=9912"/>
		<updated>2007-10-25T15:28:43Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Rivaroxaban&amp;diff=9908</id>
		<title>It07:Rivaroxaban</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Rivaroxaban&amp;diff=9908"/>
		<updated>2007-10-25T15:18:48Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;== Rivaroxaban ==&lt;br /&gt;
Rivaroxaban, or Xarelto, is a drug used to prevent or treat blood clots (it is an anti- coagulant) by inhibition of Factor Xa- an enzyme found in the coagulation cascade. Although still under development by Bayer, test results suggest that Rivaroxaban is more effective than current medication in use.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Rivaroxthing.jpg|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| 5-chloro-N-[[2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Xarelto, BAY-59-7939&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;19&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;18&amp;lt;/sub&amp;gt;ClN&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;S&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 435.88132 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 366789-02-8&lt;br /&gt;
|-&lt;br /&gt;
| Chemfinder ACX number&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/SMILES SMILES]&lt;br /&gt;
| ClC1=CC=C(C(NCC(CN2C3=CC=C(N(CCOC4)C4=O)C=C3)OC2=O)=O)S1&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
|Vapour Pressure&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
|  &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Dipole#Molecular_dipoles Dipole moment]&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Debye D]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main Hazards&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/NFPA_704 NFPA 704]&lt;br /&gt;
| &lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| N/A&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Gossypol&amp;diff=9879</id>
		<title>It07:Gossypol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Gossypol&amp;diff=9879"/>
		<updated>2007-10-25T15:02:14Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;{{Drug-Box |&lt;br /&gt;
| Box_Name = Gossypol&lt;br /&gt;
| ImageFile = Maingossypol.png&lt;br /&gt;
| IUPACName =  2,2′-bis-(Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)&lt;br /&gt;
| OtherName = Gossypol&lt;br /&gt;
| CAS_No = 303-45-7&lt;br /&gt;
| ATC_Code = &lt;br /&gt;
| PubChem = 24895349&lt;br /&gt;
| SMILES = CC(C)C1=C(C=C(C)C(C3=C(O)C(C(C=O)=C(O)C(O)=C4C(C)C)=C4C=C3C)=C2O)C2=C(C=O)C(O)=C1O&lt;br /&gt;
| Formula =  C&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;&lt;br /&gt;
| MolarMass = 518.554&lt;br /&gt;
| Bioavailability = &lt;br /&gt;
| Protein_binding&lt;br /&gt;
| Metabolism = &lt;br /&gt;
| Half_life = &lt;br /&gt;
| Excretion = &lt;br /&gt;
| Pregnancy_cat =  &lt;br /&gt;
| Cation = May be irritating to gastrointestinal tract. Large does have caused edema of lungs, | shortness of breath and paralysis in animals. Toxic to nonruminant animals, such as humans, | | by reducing the capacity the blood has to carry oxygen.&lt;br /&gt;
| Legal_status = &lt;br /&gt;
| Routes = &lt;br /&gt;
}}&lt;br /&gt;
&lt;br /&gt;
{| border=&amp;quot;1&amp;quot; cellspacing=&amp;quot;0&amp;quot; colspan=&amp;quot;2&amp;quot; cellpadding=&amp;quot;3&amp;quot; style=&amp;quot;margin: 0 0 0 0.5em; background: #FFFFFF; border-collapse: collapse; border-color: #C0C090;&amp;quot;&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/UV/VIS_spectroscopy UV-Vis]&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/UV/VIS_spectroscopy λ&amp;lt;sub&amp;gt;max&amp;lt;/sub&amp;gt;]&lt;br /&gt;
| ? [http://en.wikipedia.org/wiki/Nanometre nm]&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Extinction_coefficient Extinction coefficient], ε&lt;br /&gt;
| ? &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/Infrared_spectroscopy IR]&lt;br /&gt;
|-&lt;br /&gt;
| Major absorption bands&lt;br /&gt;
| ? [http://en.wikipedia.org/wiki/Centimetre cm]&amp;lt;sup&amp;gt;&amp;amp;minus;1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/NMR_Spectroscopy NMR]&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Proton_NMR Proton NMR] &amp;lt;!-- Link to image of spectrum --&amp;gt;&lt;br /&gt;
| &amp;amp;nbsp;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Carbon-13_NMR Carbon-13 NMR] &amp;lt;!-- Link to image of spectrum --&amp;gt;&lt;br /&gt;
| [https://www.ch.imperial.ac.uk/wiki/images/b/bd/Gossypol_C13NMR.jpg Carbon-13NMR]&lt;br /&gt;
|-&lt;br /&gt;
| Other NMR data &amp;lt;!-- Insert special data e.g. &amp;lt;sup&amp;gt;19&amp;lt;/sup&amp;gt;F chem. shifts, omit if not used --&amp;gt;&lt;br /&gt;
| &amp;amp;nbsp;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/Mass_Spectrometry MS]&lt;br /&gt;
|-&lt;br /&gt;
| Masses of &amp;lt;br&amp;gt;main fragments&lt;br /&gt;
| &amp;amp;nbsp; &amp;lt;!-- Give list of major fragments --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
Gossypol, C&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;, (IUPAC 2,2′-bis-(Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) is a pigment named after the species of cotton, &#039;&#039;Gossypium L., Malvaceae&#039;&#039;, that bears the seeds from which it is extracted. Initially it was known only as an undesirable toxin found in cotton-oil containing food-stuffs, it was thought to have potential uses as a rubber antioxidant, a stabilizer for vinyl polymers and as a potential insecticide. Today it is known primarily as a male oral contraceptive after the discovery of remarkable fertility suppressive effects in men (see history subheading).&lt;br /&gt;
(source; Merck Index)&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 80;frame 1; move 675 0 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;inlineContents&amp;gt;gossypol.PDB&lt;br /&gt;
HEADER    NONAME 18-Oct-07                                              NONE   1&lt;br /&gt;
TITLE                                                                   NONE   2&lt;br /&gt;
AUTHOR    WWW daemon apache                                             NONE   3&lt;br /&gt;
REVDAT   1  18-Oct-07     0                                             NONE   4&lt;br /&gt;
ATOM      1  C           0       6.511   0.977   2.467  0.00  0.00           C+0&lt;br /&gt;
ATOM      2  C           0       5.499   1.668   1.551  0.00  0.00           C+0&lt;br /&gt;
ATOM      3  C           0       6.209   2.748   0.731  0.00  0.00           C+0&lt;br /&gt;
ATOM      4  C           0       4.888   0.652   0.621  0.00  0.00           C+0&lt;br /&gt;
ATOM      5  C           0       3.493   0.469   0.614  0.00  0.00           C+0&lt;br /&gt;
ATOM      6  C           0       2.662   1.221   1.464  0.00  0.00           C+0&lt;br /&gt;
ATOM      7  C           0       1.316   1.031   1.444  0.00  0.00           C+0&lt;br /&gt;
ATOM      8  C           0       0.437   1.843   2.359  0.00  0.00           C+0&lt;br /&gt;
ATOM      9  C           0       0.734   0.088   0.583  0.00  0.00           C+0&lt;br /&gt;
ATOM     10  C           0      -0.735  -0.099   0.581  0.00  0.00           C+0&lt;br /&gt;
ATOM     11  C           0      -1.528   0.659  -0.275  0.00  0.00           C+0&lt;br /&gt;
ATOM     12  O           0      -0.962   1.571  -1.107  0.00  0.00           O+0&lt;br /&gt;
ATOM     13  C           0      -1.318  -1.045   1.436  0.00  0.00           C+0&lt;br /&gt;
ATOM     14  C           0      -0.441  -1.861   2.351  0.00  0.00           C+0&lt;br /&gt;
ATOM     15  C           0      -2.664  -1.235   1.453  0.00  0.00           C+0&lt;br /&gt;
ATOM     16  C           0      -3.494  -0.480   0.604  0.00  0.00           C+0&lt;br /&gt;
ATOM     17  C           0      -2.916   0.474  -0.268  0.00  0.00           C+0&lt;br /&gt;
ATOM     18  C           0      -3.791   1.255  -1.147  0.00  0.00           C+0&lt;br /&gt;
ATOM     19  C           0      -3.235   2.248  -2.063  0.00  0.00           C+0&lt;br /&gt;
ATOM     20  O           0      -3.976   2.955  -2.715  0.00  0.00           O+0&lt;br /&gt;
ATOM     21  C           0      -5.170   1.028  -1.091  0.00  0.00           C+0&lt;br /&gt;
ATOM     22  O           0      -6.004   1.735  -1.892  0.00  0.00           O+0&lt;br /&gt;
ATOM     23  C           0      -5.692   0.073  -0.211  0.00  0.00           C+0&lt;br /&gt;
ATOM     24  O           0      -7.036  -0.130  -0.175  0.00  0.00           O+0&lt;br /&gt;
ATOM     25  C           0      -4.888  -0.662   0.607  0.00  0.00           C+0&lt;br /&gt;
ATOM     26  C           0      -5.503  -1.678   1.536  0.00  0.00           C+0&lt;br /&gt;
ATOM     27  C           0      -6.516  -0.986   2.450  0.00  0.00           C+0&lt;br /&gt;
ATOM     28  C           0      -6.211  -2.757   0.714  0.00  0.00           C+0&lt;br /&gt;
ATOM     29  C           0       1.531  -0.671  -0.270  0.00  0.00           C+0&lt;br /&gt;
ATOM     30  O           0       0.967  -1.583  -1.104  0.00  0.00           O+0&lt;br /&gt;
ATOM     31  C           0       2.919  -0.485  -0.259  0.00  0.00           C+0&lt;br /&gt;
ATOM     32  C           0       3.796  -1.262  -1.140  0.00  0.00           C+0&lt;br /&gt;
ATOM     33  C           0       3.242  -2.255  -2.058  0.00  0.00           C+0&lt;br /&gt;
ATOM     34  O           0       3.968  -2.822  -2.849  0.00  0.00           O+0&lt;br /&gt;
ATOM     35  C           0       5.173  -1.031  -1.084  0.00  0.00           C+0&lt;br /&gt;
ATOM     36  O           0       6.009  -1.734  -1.887  0.00  0.00           O+0&lt;br /&gt;
ATOM     37  C           0       5.693  -0.072  -0.206  0.00  0.00           C+0&lt;br /&gt;
ATOM     38  O           0       7.036   0.134  -0.170  0.00  0.00           O+0&lt;br /&gt;
ATOM     39  H           0       6.953   1.712   3.140  0.00  0.00           H+0&lt;br /&gt;
ATOM     40  H           0       6.006   0.208   3.051  0.00  0.00           H+0&lt;br /&gt;
ATOM     41  H           0       7.294   0.519   1.864  0.00  0.00           H+0&lt;br /&gt;
ATOM     42  H           0       4.716   2.126   2.154  0.00  0.00           H+0&lt;br /&gt;
ATOM     43  H           0       6.992   2.290   0.127  0.00  0.00           H+0&lt;br /&gt;
ATOM     44  H           0       5.488   3.240   0.078  0.00  0.00           H+0&lt;br /&gt;
ATOM     45  H           0       6.651   3.483   1.403  0.00  0.00           H+0&lt;br /&gt;
ATOM     46  H           0       3.093   1.950   2.133  0.00  0.00           H+0&lt;br /&gt;
ATOM     47  H           0       0.134   2.760   1.852  0.00  0.00           H+0&lt;br /&gt;
ATOM     48  H           0      -0.448   1.264   2.622  0.00  0.00           H+0&lt;br /&gt;
ATOM     49  H           0       0.989   2.095   3.265  0.00  0.00           H+0&lt;br /&gt;
ATOM     50  H           0      -0.762   1.109  -1.933  0.00  0.00           H+0&lt;br /&gt;
ATOM     51  H           0      -0.323  -1.341   3.301  0.00  0.00           H+0&lt;br /&gt;
ATOM     52  H           0      -0.903  -2.834   2.524  0.00  0.00           H+0&lt;br /&gt;
ATOM     53  H           0       0.536  -2.001   1.888  0.00  0.00           H+0&lt;br /&gt;
ATOM     54  H           0      -3.097  -1.968   2.118  0.00  0.00           H+0&lt;br /&gt;
ATOM     55  H           0      -2.164   2.354  -2.159  0.00  0.00           H+0&lt;br /&gt;
ATOM     56  H           0      -6.096   1.232  -2.713  0.00  0.00           H+0&lt;br /&gt;
ATOM     57  H           0      -7.232  -0.820  -0.824  0.00  0.00           H+0&lt;br /&gt;
ATOM     58  H           0      -4.721  -2.136   2.141  0.00  0.00           H+0&lt;br /&gt;
ATOM     59  H           0      -7.298  -0.527   1.845  0.00  0.00           H+0&lt;br /&gt;
ATOM     60  H           0      -6.960  -1.721   3.122  0.00  0.00           H+0&lt;br /&gt;
ATOM     61  H           0      -6.012  -0.217   3.035  0.00  0.00           H+0&lt;br /&gt;
ATOM     62  H           0      -5.489  -3.250   0.063  0.00  0.00           H+0&lt;br /&gt;
ATOM     63  H           0      -6.655  -3.492   1.386  0.00  0.00           H+0&lt;br /&gt;
ATOM     64  H           0      -6.993  -2.299   0.109  0.00  0.00           H+0&lt;br /&gt;
ATOM     65  H           0       0.769  -1.121  -1.930  0.00  0.00           H+0&lt;br /&gt;
ATOM     66  H           0       2.187  -2.485  -2.032  0.00  0.00           H+0&lt;br /&gt;
ATOM     67  H           0       6.099  -1.229  -2.707  0.00  0.00           H+0&lt;br /&gt;
ATOM     68  H           0       7.231   0.823  -0.820  0.00  0.00           H+0&lt;br /&gt;
CONECT    1    2   39   40   41                                         NONE  73&lt;br /&gt;
CONECT    2    1    3    4   42                                         NONE  74&lt;br /&gt;
CONECT    3    2   43   44   45                                         NONE  75&lt;br /&gt;
CONECT    4    2   37    5    0                                         NONE  76&lt;br /&gt;
CONECT    5    4   31    6    0                                         NONE  77&lt;br /&gt;
CONECT    6    5    7   46    0                                         NONE  78&lt;br /&gt;
CONECT    7    6    8    9    0                                         NONE  79&lt;br /&gt;
CONECT    8    7   47   48   49                                         NONE  80&lt;br /&gt;
CONECT    9    7   10   29    0                                         NONE  81&lt;br /&gt;
CONECT   10    9   11   13    0                                         NONE  82&lt;br /&gt;
CONECT   11   10   17   12    0                                         NONE  83&lt;br /&gt;
CONECT   12   11   50    0    0                                         NONE  84&lt;br /&gt;
CONECT   13   10   14   15    0                                         NONE  85&lt;br /&gt;
CONECT   14   13   51   52   53                                         NONE  86&lt;br /&gt;
CONECT   15   13   16   54    0                                         NONE  87&lt;br /&gt;
CONECT   16   15   25   17    0                                         NONE  88&lt;br /&gt;
CONECT   17   16   11   18    0                                         NONE  89&lt;br /&gt;
CONECT   18   17   19   21    0                                         NONE  90&lt;br /&gt;
CONECT   19   18   20   55    0                                         NONE  91&lt;br /&gt;
CONECT   20   19    0    0    0                                         NONE  92&lt;br /&gt;
CONECT   21   18   22   23    0                                         NONE  93&lt;br /&gt;
CONECT   22   21   56    0    0                                         NONE  94&lt;br /&gt;
CONECT   23   21   24   25    0                                         NONE  95&lt;br /&gt;
CONECT   24   23   57    0    0                                         NONE  96&lt;br /&gt;
CONECT   25   23   16   26    0                                         NONE  97&lt;br /&gt;
CONECT   26   25   27   28   58                                         NONE  98&lt;br /&gt;
CONECT   27   26   59   60   61                                         NONE  99&lt;br /&gt;
CONECT   28   26   62   63   64                                         NONE 100&lt;br /&gt;
CONECT   29    9   30   31    0                                         NONE 101&lt;br /&gt;
CONECT   30   29   65    0    0                                         NONE 102&lt;br /&gt;
CONECT   31   29    5   32    0                                         NONE 103&lt;br /&gt;
CONECT   32   31   33   35    0                                         NONE 104&lt;br /&gt;
CONECT   33   32   34   66    0                                         NONE 105&lt;br /&gt;
CONECT   34   33    0    0    0                                         NONE 106&lt;br /&gt;
CONECT   35   32   36   37    0                                         NONE 107&lt;br /&gt;
CONECT   36   35   67    0    0                                         NONE 108&lt;br /&gt;
CONECT   37   35    4   38    0                                         NONE 109&lt;br /&gt;
CONECT   38   37   68    0    0                                         NONE 110&lt;br /&gt;
M  END&amp;lt;/inlineContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
= History =&lt;br /&gt;
&lt;br /&gt;
In 1929, to investigate anecdotal evidence that families who cooked with crude cottonseed oil produced fewer children, a large scale Chinese fertility survey was carried out. This study concluded that it was this oil that affected male fertility and it was determined that gossypol in the cotton seed oil could be used as a contraceptive. During the 1970s over 8,000 men were tested using this type of contraceptive and it was found that men taking a daily gossypol pill had reliable contraception. &#039;[I&#039;d like to see sources for the previous paragraph please]&#039;&lt;br /&gt;
&lt;br /&gt;
In late 2005, a team of researchers at Sunderland University found that Gossypol has been seen to help stop the spread of psoriasis, a fairly common and unpleasant, genetic skin condition, as well as reducing inflammation in sufferers. Psoriasis suffers have a genetic fault that means that under certain conditions their skin starts to produce far too many skin cells and affects more than 1 million Britains. (Source; BBC article)&lt;br /&gt;
&lt;br /&gt;
=Uses and Side Effects=&lt;br /&gt;
In 1970s, the Chinese proposed gossypol as a drug for male contraceptive use.  Studies conducted by the International Organiszation for Chemical Sciences in Development has shown that  40 of the 70 purified forms of gossypol were just as active as the original gossypol.&amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Among the side effects assiciated with the use of gossypol, the most serious was hypokalemic paralysis.  Hypokalemic paralysis&amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt; is also known that familial paralysis and occurs due to low levels of potassium in the body.  During an attack of paralysis, muschle weakness results in arms and legs.  In more severe cases, this may also affect swallowing and breathing, which can be fatal.&lt;br /&gt;
&lt;br /&gt;
Also, recovery of those who used gossypol is only 75% and can lead to other related symptoms like smaller testicular colume, and elevated follicle stimulating hormone concentrations.&amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt;&lt;br /&gt;
&lt;br /&gt;
= Known Hazards =&lt;br /&gt;
&lt;br /&gt;
May be irritating to gastrointestinal tract. Large doses have caused edema of lungs, shortness of breath and paralysis in animals. Toxic to nonruminant animals such as humans, by reducing the capacity the blood has to carry oxygen. (source; Merck Index)&lt;br /&gt;
&lt;br /&gt;
A large scale trial of gossypol was carried out in China. A high rate of hypokalemia was shown is test subjects. Hypokalemia is where there is low levels of potassium in the blood which effects the transmission between muscles and nerves. Scientists tried to remedy this by giving male monkeys gossypol along with a daily potassium tablet however this did not work. Therefore hypokalemia is an evitable side effect.&lt;br /&gt;
&lt;br /&gt;
A man who uses the drug could become partially if not fully infertile the longer they used the drug.&lt;br /&gt;
&lt;br /&gt;
= References =&lt;br /&gt;
&lt;br /&gt;
*1)http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;list_uids=9639146&amp;amp;dopt=Citation&lt;br /&gt;
*2)http://www.clevelandclinic.org/health/health-info/docs/2400/2452.asp?index=9499&lt;br /&gt;
http://www.emolecules.com/cgi-bin/more?vid=538892#&lt;br /&gt;
&lt;br /&gt;
The Merck Index- An Encylopedia of Chemicals, Drugs and Biologicals, Thirteenth edition, Merck &amp;amp; Co., Inc.&lt;br /&gt;
&lt;br /&gt;
http://news.bbc.co.uk/1/hi/england/wear/4284602.stm&lt;br /&gt;
&lt;br /&gt;
http://www.malecontraceptives.org/methods/gossypol.php&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Gossypol&amp;diff=9873</id>
		<title>It07:Gossypol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Gossypol&amp;diff=9873"/>
		<updated>2007-10-25T15:00:45Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;{{Drug-Box |&lt;br /&gt;
| Box_Name = Gossypol&lt;br /&gt;
| ImageFile = Maingossypol.png&lt;br /&gt;
| IUPACName =  2,2′-bis-(Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)&lt;br /&gt;
| OtherName = Gossypol&lt;br /&gt;
| CAS_No = 303-45-7&lt;br /&gt;
| ATC_Code = &lt;br /&gt;
| PubChem = 24895349&lt;br /&gt;
| SMILES = CC(C)C1=C(C=C(C)C(C3=C(O)C(C(C=O)=C(O)C(O)=C4C(C)C)=C4C=C3C)=C2O)C2=C(C=O)C(O)=C1O&lt;br /&gt;
| Formula =  C&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;&lt;br /&gt;
| MolarMass = 518.554&lt;br /&gt;
| Bioavailability = &lt;br /&gt;
| Protein_binding&lt;br /&gt;
| Metabolism = &lt;br /&gt;
| Half_life = &lt;br /&gt;
| Excretion = &lt;br /&gt;
| Pregnancy_cat =  &lt;br /&gt;
| Cation = May be irritating to gastrointestinal tract. Large does have caused edema of lungs, | shortness of breath and paralysis in animals. Toxic to nonruminant animals, such as humans, | | by reducing the capacity the blood has to carry oxygen.&lt;br /&gt;
| Legal_status = &lt;br /&gt;
| Routes = &lt;br /&gt;
}}&lt;br /&gt;
&lt;br /&gt;
{| border=&amp;quot;1&amp;quot; cellspacing=&amp;quot;0&amp;quot; colspan=&amp;quot;2&amp;quot; cellpadding=&amp;quot;3&amp;quot; style=&amp;quot;margin: 0 0 0 0.5em; background: #FFFFFF; border-collapse: collapse; border-color: #C0C090;&amp;quot;&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/UV/VIS_spectroscopy UV-Vis]&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/UV/VIS_spectroscopy λ&amp;lt;sub&amp;gt;max&amp;lt;/sub&amp;gt;]&lt;br /&gt;
| ? [http://en.wikipedia.org/wiki/Nanometre nm]&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Extinction_coefficient Extinction coefficient], ε&lt;br /&gt;
| ? &lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/Infrared_spectroscopy IR]&lt;br /&gt;
|-&lt;br /&gt;
| Major absorption bands&lt;br /&gt;
| ? [http://en.wikipedia.org/wiki/Centimetre cm]&amp;lt;sup&amp;gt;&amp;amp;minus;1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/NMR_Spectroscopy NMR]&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Proton_NMR Proton NMR] &amp;lt;!-- Link to image of spectrum --&amp;gt;&lt;br /&gt;
| &amp;amp;nbsp;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Carbon-13_NMR Carbon-13 NMR] &amp;lt;!-- Link to image of spectrum --&amp;gt;&lt;br /&gt;
| [https://www.ch.imperial.ac.uk/wiki/index.php/Image:Gossypol_C13NMR.jpg Carbon-13NMR]&lt;br /&gt;
|-&lt;br /&gt;
| Other NMR data &amp;lt;!-- Insert special data e.g. &amp;lt;sup&amp;gt;19&amp;lt;/sup&amp;gt;F chem. shifts, omit if not used --&amp;gt;&lt;br /&gt;
| &amp;amp;nbsp;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [http://en.wikipedia.org/wiki/Mass_Spectrometry MS]&lt;br /&gt;
|-&lt;br /&gt;
| Masses of &amp;lt;br&amp;gt;main fragments&lt;br /&gt;
| &amp;amp;nbsp; &amp;lt;!-- Give list of major fragments --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
Gossypol, C&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;30&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;, (IUPAC 2,2′-bis-(Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) is a pigment named after the species of cotton, &#039;&#039;Gossypium L., Malvaceae&#039;&#039;, that bears the seeds from which it is extracted. Initially it was known only as an undesirable toxin found in cotton-oil containing food-stuffs, it was thought to have potential uses as a rubber antioxidant, a stabilizer for vinyl polymers and as a potential insecticide. Today it is known primarily as a male oral contraceptive after the discovery of remarkable fertility suppressive effects in men (see history subheading).&lt;br /&gt;
(source; Merck Index)&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 80;frame 1; move 675 0 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;inlineContents&amp;gt;gossypol.PDB&lt;br /&gt;
HEADER    NONAME 18-Oct-07                                              NONE   1&lt;br /&gt;
TITLE                                                                   NONE   2&lt;br /&gt;
AUTHOR    WWW daemon apache                                             NONE   3&lt;br /&gt;
REVDAT   1  18-Oct-07     0                                             NONE   4&lt;br /&gt;
ATOM      1  C           0       6.511   0.977   2.467  0.00  0.00           C+0&lt;br /&gt;
ATOM      2  C           0       5.499   1.668   1.551  0.00  0.00           C+0&lt;br /&gt;
ATOM      3  C           0       6.209   2.748   0.731  0.00  0.00           C+0&lt;br /&gt;
ATOM      4  C           0       4.888   0.652   0.621  0.00  0.00           C+0&lt;br /&gt;
ATOM      5  C           0       3.493   0.469   0.614  0.00  0.00           C+0&lt;br /&gt;
ATOM      6  C           0       2.662   1.221   1.464  0.00  0.00           C+0&lt;br /&gt;
ATOM      7  C           0       1.316   1.031   1.444  0.00  0.00           C+0&lt;br /&gt;
ATOM      8  C           0       0.437   1.843   2.359  0.00  0.00           C+0&lt;br /&gt;
ATOM      9  C           0       0.734   0.088   0.583  0.00  0.00           C+0&lt;br /&gt;
ATOM     10  C           0      -0.735  -0.099   0.581  0.00  0.00           C+0&lt;br /&gt;
ATOM     11  C           0      -1.528   0.659  -0.275  0.00  0.00           C+0&lt;br /&gt;
ATOM     12  O           0      -0.962   1.571  -1.107  0.00  0.00           O+0&lt;br /&gt;
ATOM     13  C           0      -1.318  -1.045   1.436  0.00  0.00           C+0&lt;br /&gt;
ATOM     14  C           0      -0.441  -1.861   2.351  0.00  0.00           C+0&lt;br /&gt;
ATOM     15  C           0      -2.664  -1.235   1.453  0.00  0.00           C+0&lt;br /&gt;
ATOM     16  C           0      -3.494  -0.480   0.604  0.00  0.00           C+0&lt;br /&gt;
ATOM     17  C           0      -2.916   0.474  -0.268  0.00  0.00           C+0&lt;br /&gt;
ATOM     18  C           0      -3.791   1.255  -1.147  0.00  0.00           C+0&lt;br /&gt;
ATOM     19  C           0      -3.235   2.248  -2.063  0.00  0.00           C+0&lt;br /&gt;
ATOM     20  O           0      -3.976   2.955  -2.715  0.00  0.00           O+0&lt;br /&gt;
ATOM     21  C           0      -5.170   1.028  -1.091  0.00  0.00           C+0&lt;br /&gt;
ATOM     22  O           0      -6.004   1.735  -1.892  0.00  0.00           O+0&lt;br /&gt;
ATOM     23  C           0      -5.692   0.073  -0.211  0.00  0.00           C+0&lt;br /&gt;
ATOM     24  O           0      -7.036  -0.130  -0.175  0.00  0.00           O+0&lt;br /&gt;
ATOM     25  C           0      -4.888  -0.662   0.607  0.00  0.00           C+0&lt;br /&gt;
ATOM     26  C           0      -5.503  -1.678   1.536  0.00  0.00           C+0&lt;br /&gt;
ATOM     27  C           0      -6.516  -0.986   2.450  0.00  0.00           C+0&lt;br /&gt;
ATOM     28  C           0      -6.211  -2.757   0.714  0.00  0.00           C+0&lt;br /&gt;
ATOM     29  C           0       1.531  -0.671  -0.270  0.00  0.00           C+0&lt;br /&gt;
ATOM     30  O           0       0.967  -1.583  -1.104  0.00  0.00           O+0&lt;br /&gt;
ATOM     31  C           0       2.919  -0.485  -0.259  0.00  0.00           C+0&lt;br /&gt;
ATOM     32  C           0       3.796  -1.262  -1.140  0.00  0.00           C+0&lt;br /&gt;
ATOM     33  C           0       3.242  -2.255  -2.058  0.00  0.00           C+0&lt;br /&gt;
ATOM     34  O           0       3.968  -2.822  -2.849  0.00  0.00           O+0&lt;br /&gt;
ATOM     35  C           0       5.173  -1.031  -1.084  0.00  0.00           C+0&lt;br /&gt;
ATOM     36  O           0       6.009  -1.734  -1.887  0.00  0.00           O+0&lt;br /&gt;
ATOM     37  C           0       5.693  -0.072  -0.206  0.00  0.00           C+0&lt;br /&gt;
ATOM     38  O           0       7.036   0.134  -0.170  0.00  0.00           O+0&lt;br /&gt;
ATOM     39  H           0       6.953   1.712   3.140  0.00  0.00           H+0&lt;br /&gt;
ATOM     40  H           0       6.006   0.208   3.051  0.00  0.00           H+0&lt;br /&gt;
ATOM     41  H           0       7.294   0.519   1.864  0.00  0.00           H+0&lt;br /&gt;
ATOM     42  H           0       4.716   2.126   2.154  0.00  0.00           H+0&lt;br /&gt;
ATOM     43  H           0       6.992   2.290   0.127  0.00  0.00           H+0&lt;br /&gt;
ATOM     44  H           0       5.488   3.240   0.078  0.00  0.00           H+0&lt;br /&gt;
ATOM     45  H           0       6.651   3.483   1.403  0.00  0.00           H+0&lt;br /&gt;
ATOM     46  H           0       3.093   1.950   2.133  0.00  0.00           H+0&lt;br /&gt;
ATOM     47  H           0       0.134   2.760   1.852  0.00  0.00           H+0&lt;br /&gt;
ATOM     48  H           0      -0.448   1.264   2.622  0.00  0.00           H+0&lt;br /&gt;
ATOM     49  H           0       0.989   2.095   3.265  0.00  0.00           H+0&lt;br /&gt;
ATOM     50  H           0      -0.762   1.109  -1.933  0.00  0.00           H+0&lt;br /&gt;
ATOM     51  H           0      -0.323  -1.341   3.301  0.00  0.00           H+0&lt;br /&gt;
ATOM     52  H           0      -0.903  -2.834   2.524  0.00  0.00           H+0&lt;br /&gt;
ATOM     53  H           0       0.536  -2.001   1.888  0.00  0.00           H+0&lt;br /&gt;
ATOM     54  H           0      -3.097  -1.968   2.118  0.00  0.00           H+0&lt;br /&gt;
ATOM     55  H           0      -2.164   2.354  -2.159  0.00  0.00           H+0&lt;br /&gt;
ATOM     56  H           0      -6.096   1.232  -2.713  0.00  0.00           H+0&lt;br /&gt;
ATOM     57  H           0      -7.232  -0.820  -0.824  0.00  0.00           H+0&lt;br /&gt;
ATOM     58  H           0      -4.721  -2.136   2.141  0.00  0.00           H+0&lt;br /&gt;
ATOM     59  H           0      -7.298  -0.527   1.845  0.00  0.00           H+0&lt;br /&gt;
ATOM     60  H           0      -6.960  -1.721   3.122  0.00  0.00           H+0&lt;br /&gt;
ATOM     61  H           0      -6.012  -0.217   3.035  0.00  0.00           H+0&lt;br /&gt;
ATOM     62  H           0      -5.489  -3.250   0.063  0.00  0.00           H+0&lt;br /&gt;
ATOM     63  H           0      -6.655  -3.492   1.386  0.00  0.00           H+0&lt;br /&gt;
ATOM     64  H           0      -6.993  -2.299   0.109  0.00  0.00           H+0&lt;br /&gt;
ATOM     65  H           0       0.769  -1.121  -1.930  0.00  0.00           H+0&lt;br /&gt;
ATOM     66  H           0       2.187  -2.485  -2.032  0.00  0.00           H+0&lt;br /&gt;
ATOM     67  H           0       6.099  -1.229  -2.707  0.00  0.00           H+0&lt;br /&gt;
ATOM     68  H           0       7.231   0.823  -0.820  0.00  0.00           H+0&lt;br /&gt;
CONECT    1    2   39   40   41                                         NONE  73&lt;br /&gt;
CONECT    2    1    3    4   42                                         NONE  74&lt;br /&gt;
CONECT    3    2   43   44   45                                         NONE  75&lt;br /&gt;
CONECT    4    2   37    5    0                                         NONE  76&lt;br /&gt;
CONECT    5    4   31    6    0                                         NONE  77&lt;br /&gt;
CONECT    6    5    7   46    0                                         NONE  78&lt;br /&gt;
CONECT    7    6    8    9    0                                         NONE  79&lt;br /&gt;
CONECT    8    7   47   48   49                                         NONE  80&lt;br /&gt;
CONECT    9    7   10   29    0                                         NONE  81&lt;br /&gt;
CONECT   10    9   11   13    0                                         NONE  82&lt;br /&gt;
CONECT   11   10   17   12    0                                         NONE  83&lt;br /&gt;
CONECT   12   11   50    0    0                                         NONE  84&lt;br /&gt;
CONECT   13   10   14   15    0                                         NONE  85&lt;br /&gt;
CONECT   14   13   51   52   53                                         NONE  86&lt;br /&gt;
CONECT   15   13   16   54    0                                         NONE  87&lt;br /&gt;
CONECT   16   15   25   17    0                                         NONE  88&lt;br /&gt;
CONECT   17   16   11   18    0                                         NONE  89&lt;br /&gt;
CONECT   18   17   19   21    0                                         NONE  90&lt;br /&gt;
CONECT   19   18   20   55    0                                         NONE  91&lt;br /&gt;
CONECT   20   19    0    0    0                                         NONE  92&lt;br /&gt;
CONECT   21   18   22   23    0                                         NONE  93&lt;br /&gt;
CONECT   22   21   56    0    0                                         NONE  94&lt;br /&gt;
CONECT   23   21   24   25    0                                         NONE  95&lt;br /&gt;
CONECT   24   23   57    0    0                                         NONE  96&lt;br /&gt;
CONECT   25   23   16   26    0                                         NONE  97&lt;br /&gt;
CONECT   26   25   27   28   58                                         NONE  98&lt;br /&gt;
CONECT   27   26   59   60   61                                         NONE  99&lt;br /&gt;
CONECT   28   26   62   63   64                                         NONE 100&lt;br /&gt;
CONECT   29    9   30   31    0                                         NONE 101&lt;br /&gt;
CONECT   30   29   65    0    0                                         NONE 102&lt;br /&gt;
CONECT   31   29    5   32    0                                         NONE 103&lt;br /&gt;
CONECT   32   31   33   35    0                                         NONE 104&lt;br /&gt;
CONECT   33   32   34   66    0                                         NONE 105&lt;br /&gt;
CONECT   34   33    0    0    0                                         NONE 106&lt;br /&gt;
CONECT   35   32   36   37    0                                         NONE 107&lt;br /&gt;
CONECT   36   35   67    0    0                                         NONE 108&lt;br /&gt;
CONECT   37   35    4   38    0                                         NONE 109&lt;br /&gt;
CONECT   38   37   68    0    0                                         NONE 110&lt;br /&gt;
M  END&amp;lt;/inlineContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
= History =&lt;br /&gt;
&lt;br /&gt;
In 1929, to investigate anecdotal evidence that families who cooked with crude cottonseed oil produced fewer children, a large scale Chinese fertility survey was carried out. This study concluded that it was this oil that affected male fertility and it was determined that gossypol in the cotton seed oil could be used as a contraceptive. During the 1970s over 8,000 men were tested using this type of contraceptive and it was found that men taking a daily gossypol pill had reliable contraception. &#039;[I&#039;d like to see sources for the previous paragraph please]&#039;&lt;br /&gt;
&lt;br /&gt;
In late 2005, a team of researchers at Sunderland University found that Gossypol has been seen to help stop the spread of psoriasis, a fairly common and unpleasant, genetic skin condition, as well as reducing inflammation in sufferers. Psoriasis suffers have a genetic fault that means that under certain conditions their skin starts to produce far too many skin cells and affects more than 1 million Britains. (Source; BBC article)&lt;br /&gt;
&lt;br /&gt;
=Uses and Side Effects=&lt;br /&gt;
In 1970s, the Chinese proposed gossypol as a drug for male contraceptive use.  Studies conducted by the International Organiszation for Chemical Sciences in Development has shown that  40 of the 70 purified forms of gossypol were just as active as the original gossypol.&amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Among the side effects assiciated with the use of gossypol, the most serious was hypokalemic paralysis.  Hypokalemic paralysis&amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt; is also known that familial paralysis and occurs due to low levels of potassium in the body.  During an attack of paralysis, muschle weakness results in arms and legs.  In more severe cases, this may also affect swallowing and breathing, which can be fatal.&lt;br /&gt;
&lt;br /&gt;
Also, recovery of those who used gossypol is only 75% and can lead to other related symptoms like smaller testicular colume, and elevated follicle stimulating hormone concentrations.&amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt;&lt;br /&gt;
&lt;br /&gt;
= Known Hazards =&lt;br /&gt;
&lt;br /&gt;
May be irritating to gastrointestinal tract. Large doses have caused edema of lungs, shortness of breath and paralysis in animals. Toxic to nonruminant animals such as humans, by reducing the capacity the blood has to carry oxygen. (source; Merck Index)&lt;br /&gt;
&lt;br /&gt;
A large scale trial of gossypol was carried out in China. A high rate of hypokalemia was shown is test subjects. Hypokalemia is where there is low levels of potassium in the blood which effects the transmission between muscles and nerves. Scientists tried to remedy this by giving male monkeys gossypol along with a daily potassium tablet however this did not work. Therefore hypokalemia is an evitable side effect.&lt;br /&gt;
&lt;br /&gt;
A man who uses the drug could become partially if not fully infertile the longer they used the drug.&lt;br /&gt;
&lt;br /&gt;
= References =&lt;br /&gt;
&lt;br /&gt;
*1)http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;list_uids=9639146&amp;amp;dopt=Citation&lt;br /&gt;
*2)http://www.clevelandclinic.org/health/health-info/docs/2400/2452.asp?index=9499&lt;br /&gt;
http://www.emolecules.com/cgi-bin/more?vid=538892#&lt;br /&gt;
&lt;br /&gt;
The Merck Index- An Encylopedia of Chemicals, Drugs and Biologicals, Thirteenth edition, Merck &amp;amp; Co., Inc.&lt;br /&gt;
&lt;br /&gt;
http://news.bbc.co.uk/1/hi/england/wear/4284602.stm&lt;br /&gt;
&lt;br /&gt;
http://www.malecontraceptives.org/methods/gossypol.php&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:name_of_project&amp;diff=9688</id>
		<title>It07:name of project</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:name_of_project&amp;diff=9688"/>
		<updated>2007-10-25T13:30:14Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: /* References */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&#039;&#039;&#039;Vitamin C&#039;&#039;&#039;14:26, 18 October 2007 (BST)[[User:Zl406|Zl406]] &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
[[Image:Vitaminc.jpg|thumb|right|200|A 3D image of Vitamin C]]&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;&amp;quot;&lt;br /&gt;
! {{chembox header}} | Vitamin C &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; width=&amp;quot;400&amp;quot; colspan=&amp;quot;4&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | &lt;br /&gt;
[[Image:Vitaminc.jpg|thumb |centre|300|A 3D image of Vitamin C]]&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; width=&amp;quot;400&amp;quot; colspan=&amp;quot;4&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | &lt;br /&gt;
[[Image:Vitamin c.png|thumb|centre|300|A plane view of Vitamin C]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|-&lt;br /&gt;
| [[International Union of Pure and Applied Chemistry nomenclature|Systematic name]]&lt;br /&gt;
| (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one &amp;lt;!-- e.g. Iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Ascorbic acid &amp;lt;!-- e.g. Ferrous chloride etc, + linked mineral names --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Chemical formula|Molecular formula]]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; &amp;lt;!-- e.g. Na&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;CO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Simplified molecular input line entry specification|SMILES]] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| O=C1[C@]([C@@H](O)CO)([H])OC(O)=C1O&lt;br /&gt;
|-&lt;br /&gt;
| [[Molar mass]]&lt;br /&gt;
| 176.12412 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| ? &amp;lt;!-- e.g. pale yellow solid, [[hygroscopic]] --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[CAS registry number|CAS number]]&lt;br /&gt;
| [?-?-?]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [[Density]] and [[Phase (matter)|phase]]&lt;br /&gt;
| ? g/cm³, ? &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Solubility]] in [[Water_(molecule)|water]]&lt;br /&gt;
| ? g/100 ml (?°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [[Melting point]]&lt;br /&gt;
| ?°C (? K) &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Boiling point]]&lt;br /&gt;
| ?°C (? K)&lt;br /&gt;
|-&lt;br /&gt;
| [[Acid dissociation constant|Acidity]] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
| [[Acid dissociation constant|Basicity]] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
| [[Specific rotation|Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;]] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| ?°&lt;br /&gt;
|-&lt;br /&gt;
| [[Viscosity]]&lt;br /&gt;
| ? [[Poise|cP]] at ?°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [[Orbital_hybridisation#Molecule_shape|Molecular shape]] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Coordination geometry|Coordination&amp;lt;br /&amp;gt;geometry]] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Crystal structure]] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| ? [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| ? &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| &amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| ?°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: ? &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]]&lt;br /&gt;
| [[Refractive index|&#039;&#039;n&#039;&#039;]], [[Dielectric constant|ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;]], etc.&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]]&lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related [[?]] &amp;lt;!-- PLEASE INSERT FUNCTIONAL GROUP (e.g. [[aldehyde]]) FOR ORGANICS, please omit if not applicable --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- Insert related organics e.g. on formaldehyde page put [[acetaldehyde]] --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds&lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;.&lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Vitamin c&#039;&#039;&#039; is also called &#039;&#039;&#039;L-ascorbate&#039;&#039;&#039;, it is known as the &#039;&#039;&#039;ascorbic acid&#039;&#039;&#039;, which is the only vitamin is &#039;&#039;water-soluble&#039;&#039;,  unlike other vitamins, most of them are &#039;&#039;fat-soluble&#039;&#039;. Unlike most mammals, humans do not have the ability to make their own vitamin C. so we have to obtain vitamin C daily in our diet. It is very essetial to all living animals to form the &#039;&#039;metabolic&#039;&#039; reactions and as for all living organisms, plants in this case, human is the only excption. Vitamin C &#039;&#039;deficiency accelerates aging&#039;&#039;, this is because it act as an &#039;&#039;antioxidant&#039;&#039; in the body, so it protect the  living body from over oxdative stress. Finally it also involves in sereval &#039;&#039;vital&#039;&#039; &#039;&#039;enzymatic&#039;&#039; reactions.&lt;br /&gt;
But the daily requirement of vitamin c is still under debating since the human body dose not store any vitamin c.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 100; cpk -25;frame 0;MultipleBonds ON; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;inlineContents&amp;gt;water.mol&lt;br /&gt;
  REMARK   MSI WebLab Viewer PDB file&lt;br /&gt;
REMARK   Created:  Thu Oct 18 15:04:59 GMT Daylight Time 2007&lt;br /&gt;
ATOM      1  C   (NU A   0       2.584   0.846  -0.260  1.00  0.00              &lt;br /&gt;
ATOM      2  C   (NU A   0       1.539  -0.166   0.212  1.00  0.00              &lt;br /&gt;
ATOM      3  C   (NU A   0       0.302  -0.079  -0.684  1.00  0.00              &lt;br /&gt;
ATOM      4  C   (NU A   0      -0.748  -1.074  -0.233  1.00  0.00              &lt;br /&gt;
ATOM      5  O   (NU A   0      -0.646  -2.286  -0.187  1.00  0.00              &lt;br /&gt;
ATOM      6  C   (NU A   0      -1.859  -0.299   0.117  1.00  0.00              &lt;br /&gt;
ATOM      7  C   (NU A   0      -1.574   1.015  -0.077  1.00  0.00              &lt;br /&gt;
ATOM      8  O   (NU A   0      -0.327   1.202  -0.543  1.00  0.00              &lt;br /&gt;
ATOM      9  O   (NU A   0      -2.442   2.018   0.170  1.00  0.00              &lt;br /&gt;
ATOM     10  O   (NU A   0      -3.044  -0.787   0.583  1.00  0.00              &lt;br /&gt;
ATOM     11  O   (NU A   0       2.086  -1.484   0.141  1.00  0.00              &lt;br /&gt;
ATOM     12  O   (NU A   0       3.690   0.847   0.644  1.00  0.00              &lt;br /&gt;
ATOM     13  H   (NU A   0       2.930   0.573  -1.257  1.00  0.00              &lt;br /&gt;
ATOM     14  H   (NU A   0       2.139   1.841  -0.290  1.00  0.00              &lt;br /&gt;
ATOM     15  H   (NU A   0       1.258   0.055   1.242  1.00  0.00              &lt;br /&gt;
ATOM     16  H   (NU A   0       0.574  -0.258  -1.724  1.00  0.00              &lt;br /&gt;
ATOM     17  H   (NU A   0      -1.988   2.842  -0.052  1.00  0.00              &lt;br /&gt;
ATOM     18  H   (NU A   0      -3.619  -0.025   0.739  1.00  0.00              &lt;br /&gt;
ATOM     19  H   (NU A   0       2.321  -1.640  -0.784  1.00  0.00              &lt;br /&gt;
ATOM     20  H   (NU A   0       4.324   1.497   0.311  1.00  0.00              &lt;br /&gt;
M  END&amp;lt;/inlineContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Beauty uses ==&lt;br /&gt;
=== Whitening effect ===&lt;br /&gt;
=== Regenerating skin ===&lt;br /&gt;
&lt;br /&gt;
== Daily requirement ==&lt;br /&gt;
== Toxicity  ==&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
[[spectroscopic properties|vitamin in diet ]]&lt;br /&gt;
{| &lt;br /&gt;
| mole || Entry 2 || Entry 3&lt;br /&gt;
|}&lt;br /&gt;
{| border=&amp;quot;1&amp;quot;&lt;br /&gt;
|+ Contents &lt;br /&gt;
! Column heading 1 !! Column heading 2 !! Column heading 3&lt;br /&gt;
|-&lt;br /&gt;
! Row heading 1&lt;br /&gt;
| Cell 2 || Cell 3&lt;br /&gt;
|-&lt;br /&gt;
! Row heading A&lt;br /&gt;
|Cell B ||Cell C&lt;br /&gt;
|}&lt;br /&gt;
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5785#Properties&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:name_of_project&amp;diff=9687</id>
		<title>It07:name of project</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:name_of_project&amp;diff=9687"/>
		<updated>2007-10-25T13:28:43Z</updated>

		<summary type="html">&lt;p&gt;Yyl206: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&#039;&#039;&#039;Vitamin C&#039;&#039;&#039;14:26, 18 October 2007 (BST)[[User:Zl406|Zl406]] &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
[[Image:Vitaminc.jpg|thumb|right|200|A 3D image of Vitamin C]]&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;&amp;quot;&lt;br /&gt;
! {{chembox header}} | Vitamin C &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; width=&amp;quot;400&amp;quot; colspan=&amp;quot;4&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | &lt;br /&gt;
[[Image:Vitaminc.jpg|thumb |centre|300|A 3D image of Vitamin C]]&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; width=&amp;quot;400&amp;quot; colspan=&amp;quot;4&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | &lt;br /&gt;
[[Image:Vitamin c.png|thumb|centre|300|A plane view of Vitamin C]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|-&lt;br /&gt;
| [[International Union of Pure and Applied Chemistry nomenclature|Systematic name]]&lt;br /&gt;
| (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one &amp;lt;!-- e.g. Iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Ascorbic acid &amp;lt;!-- e.g. Ferrous chloride etc, + linked mineral names --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Chemical formula|Molecular formula]]&lt;br /&gt;
| C&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; &amp;lt;!-- e.g. Na&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;CO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Simplified molecular input line entry specification|SMILES]] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| O=C1[C@]([C@@H](O)CO)([H])OC(O)=C1O&lt;br /&gt;
|-&lt;br /&gt;
| [[Molar mass]]&lt;br /&gt;
| 176.12412 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| ? &amp;lt;!-- e.g. pale yellow solid, [[hygroscopic]] --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[CAS registry number|CAS number]]&lt;br /&gt;
| [?-?-?]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [[Density]] and [[Phase (matter)|phase]]&lt;br /&gt;
| ? g/cm³, ? &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Solubility]] in [[Water_(molecule)|water]]&lt;br /&gt;
| ? g/100 ml (?°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [[Melting point]]&lt;br /&gt;
| ?°C (? K) &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Boiling point]]&lt;br /&gt;
| ?°C (? K)&lt;br /&gt;
|-&lt;br /&gt;
| [[Acid dissociation constant|Acidity]] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
| [[Acid dissociation constant|Basicity]] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
| [[Specific rotation|Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;]] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| ?°&lt;br /&gt;
|-&lt;br /&gt;
| [[Viscosity]]&lt;br /&gt;
| ? [[Poise|cP]] at ?°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [[Orbital_hybridisation#Molecule_shape|Molecular shape]] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Coordination geometry|Coordination&amp;lt;br /&amp;gt;geometry]] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Crystal structure]] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| ? [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| ? &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| &amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| ?°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: ? &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]]&lt;br /&gt;
| [[Refractive index|&#039;&#039;n&#039;&#039;]], [[Dielectric constant|ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;]], etc.&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]]&lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related [[?]] &amp;lt;!-- PLEASE INSERT FUNCTIONAL GROUP (e.g. [[aldehyde]]) FOR ORGANICS, please omit if not applicable --&amp;gt;&lt;br /&gt;
| ? &amp;lt;!-- Insert related organics e.g. on formaldehyde page put [[acetaldehyde]] --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds&lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;.&lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| ?&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Vitamin c&#039;&#039;&#039; is also called &#039;&#039;&#039;L-ascorbate&#039;&#039;&#039;, it is known as the &#039;&#039;&#039;ascorbic acid&#039;&#039;&#039;, which is the only vitamin is &#039;&#039;water-soluble&#039;&#039;,  unlike other vitamins, most of them are &#039;&#039;fat-soluble&#039;&#039;. Unlike most mammals, humans do not have the ability to make their own vitamin C. so we have to obtain vitamin C daily in our diet. It is very essetial to all living animals to form the &#039;&#039;metabolic&#039;&#039; reactions and as for all living organisms, plants in this case, human is the only excption. Vitamin C &#039;&#039;deficiency accelerates aging&#039;&#039;, this is because it act as an &#039;&#039;antioxidant&#039;&#039; in the body, so it protect the  living body from over oxdative stress. Finally it also involves in sereval &#039;&#039;vital&#039;&#039; &#039;&#039;enzymatic&#039;&#039; reactions.&lt;br /&gt;
But the daily requirement of vitamin c is still under debating since the human body dose not store any vitamin c.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 100; cpk -25;frame 0;MultipleBonds ON; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;inlineContents&amp;gt;water.mol&lt;br /&gt;
  REMARK   MSI WebLab Viewer PDB file&lt;br /&gt;
REMARK   Created:  Thu Oct 18 15:04:59 GMT Daylight Time 2007&lt;br /&gt;
ATOM      1  C   (NU A   0       2.584   0.846  -0.260  1.00  0.00              &lt;br /&gt;
ATOM      2  C   (NU A   0       1.539  -0.166   0.212  1.00  0.00              &lt;br /&gt;
ATOM      3  C   (NU A   0       0.302  -0.079  -0.684  1.00  0.00              &lt;br /&gt;
ATOM      4  C   (NU A   0      -0.748  -1.074  -0.233  1.00  0.00              &lt;br /&gt;
ATOM      5  O   (NU A   0      -0.646  -2.286  -0.187  1.00  0.00              &lt;br /&gt;
ATOM      6  C   (NU A   0      -1.859  -0.299   0.117  1.00  0.00              &lt;br /&gt;
ATOM      7  C   (NU A   0      -1.574   1.015  -0.077  1.00  0.00              &lt;br /&gt;
ATOM      8  O   (NU A   0      -0.327   1.202  -0.543  1.00  0.00              &lt;br /&gt;
ATOM      9  O   (NU A   0      -2.442   2.018   0.170  1.00  0.00              &lt;br /&gt;
ATOM     10  O   (NU A   0      -3.044  -0.787   0.583  1.00  0.00              &lt;br /&gt;
ATOM     11  O   (NU A   0       2.086  -1.484   0.141  1.00  0.00              &lt;br /&gt;
ATOM     12  O   (NU A   0       3.690   0.847   0.644  1.00  0.00              &lt;br /&gt;
ATOM     13  H   (NU A   0       2.930   0.573  -1.257  1.00  0.00              &lt;br /&gt;
ATOM     14  H   (NU A   0       2.139   1.841  -0.290  1.00  0.00              &lt;br /&gt;
ATOM     15  H   (NU A   0       1.258   0.055   1.242  1.00  0.00              &lt;br /&gt;
ATOM     16  H   (NU A   0       0.574  -0.258  -1.724  1.00  0.00              &lt;br /&gt;
ATOM     17  H   (NU A   0      -1.988   2.842  -0.052  1.00  0.00              &lt;br /&gt;
ATOM     18  H   (NU A   0      -3.619  -0.025   0.739  1.00  0.00              &lt;br /&gt;
ATOM     19  H   (NU A   0       2.321  -1.640  -0.784  1.00  0.00              &lt;br /&gt;
ATOM     20  H   (NU A   0       4.324   1.497   0.311  1.00  0.00              &lt;br /&gt;
M  END&amp;lt;/inlineContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Beauty uses ==&lt;br /&gt;
=== Whitening effect ===&lt;br /&gt;
=== Regenerating skin ===&lt;br /&gt;
&lt;br /&gt;
== Daily requirement ==&lt;br /&gt;
== Toxicity  ==&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
[[spectroscopic properties|vitamin in diet ]]&lt;br /&gt;
{| &lt;br /&gt;
| mole || Entry 2 || Entry 3&lt;br /&gt;
|}&lt;br /&gt;
{| border=&amp;quot;1&amp;quot;&lt;br /&gt;
|+ Contents &lt;br /&gt;
! Column heading 1 !! Column heading 2 !! Column heading 3&lt;br /&gt;
|-&lt;br /&gt;
! Row heading 1&lt;br /&gt;
| Cell 2 || Cell 3&lt;br /&gt;
|-&lt;br /&gt;
! Row heading A&lt;br /&gt;
|Cell B ||Cell C&lt;br /&gt;
|}&lt;/div&gt;</summary>
		<author><name>Yyl206</name></author>
	</entry>
</feed>