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	<id>https://chemwiki.ch.ic.ac.uk/api.php?action=feedcontributions&amp;feedformat=atom&amp;user=Whc06</id>
	<title>ChemWiki - User contributions [en]</title>
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	<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/wiki/Special:Contributions/Whc06"/>
	<updated>2026-04-05T01:55:10Z</updated>
	<subtitle>User contributions</subtitle>
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	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Sertraline&amp;diff=11285</id>
		<title>It07:Sertraline</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Sertraline&amp;diff=11285"/>
		<updated>2007-11-19T14:36:31Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;Setraline hydrochloride is used as an antidepressant&lt;br /&gt;
&lt;br /&gt;
&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:sertralinecopley.png|thumb|right|200]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| {{{IUPACName}}}&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| {{{OtherNames}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| {{{Formula}}} &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| {{{SMILES}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| {{{MolarMass}}}&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| {{{CASNo}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| {{{Density}}} g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| {{{Bp}}} K&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| {{{Rotation}}}°&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| {{{RTECS}}}&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
[[Image:sertralinecopley.png|thumb|right|200]]&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;17140.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11281</id>
		<title>It07:Aspirin</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11281"/>
		<updated>2007-11-19T14:34:08Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Aspirin.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-acetoxybenzoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Acetylsalicylic acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;9&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| CC(OC1=C(C(O)=O)C=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-78-2&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 180.16 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Density&lt;br /&gt;
| 1.40gcm&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 140&amp;amp;nbsp;°C (284&amp;amp;nbsp;°F) (decomposes)&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| 138-140&amp;amp;nbsp;°C (280-284&amp;amp;nbsp;°F)&lt;br /&gt;
|-&lt;br /&gt;
| Solubility in water&lt;br /&gt;
| 10mg / ml (20&amp;amp;nbsp;°C)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Aspirin, also known as acetylsalicylic acid, is a salicylate drug which usually uses as an analgesic to relieve pains and minor aches, an antipyretic to reduce fever, or as an anti-inflammatory. Besides this, it also has the antiplatelet effect that causes “blood-thinning” to be used in long term. Aspirin can prevent the heart attack in low doses.&lt;br /&gt;
&lt;br /&gt;
Aspirin was the member of the class of drugs which is known as non-steroidal anti0inflammatory drugs (NSAIDs). Here not all of them are salicylates. But they all &lt;br /&gt;
have the similar effects.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;24847.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
==Synthesis==&lt;br /&gt;
&lt;br /&gt;
It’s classified as an esterification reaction for the synthesis of aspirin in which the alcohol group from the salicylic acid reacts with the acetic anhydride to form an ester.&lt;br /&gt;
&lt;br /&gt;
Generally, aspirin is synthesized via a two step process. First of all, the phenol that normally generated from coal tar, reacts with a sodium base to form a sodium phenolate. Under high pressure and temperature, it reacts with carbon dioxide to yield salicylate. Finally, it’s acidified to form salicylic acid. This process is called the Kolbe-Schmitt reaction.&lt;br /&gt;
&lt;br /&gt;
Secondly, the salicylic acid is then acetylated via an acetic anhydride, which yields aspirin and acetic acid as a side-product. As it’s hard for the extraction from an aqueous state, this reaction usually produces a low yield. Another method in getting higher yield is to acidify with phosphoric acid, followed by heating under reflux in 40-60 minutes.&lt;br /&gt;
&lt;br /&gt;
In addition, the original synthesis of aspirin from salicylic acid involves acetylation with acetyl chloride. Therefore hydrochloric acid will be formed as a by-product and it is very corrosive and environmentally hazardous. However in the second step above, salicylic acid can be acetylated with acetic anhydride which is a better acylating agent. Then acetic acid formed as the side-product doesn’t contain the harmful properties of the hydrochloric acid. Furthermore, the acetic acid can be recycled. So it’s much better to use acetic anhydride as an acetylating agent.&lt;br /&gt;
&lt;br /&gt;
In the synthesis, a smell of vinegar can be altered if a high concentration of aspirin is used. It is because aspirin could undergo autocatalysis in a moistened condition which then yields salicylic acid and acetic acid.&lt;br /&gt;
&lt;br /&gt;
[[Image:Reaction.JPG]]&lt;br /&gt;
&lt;br /&gt;
==Therapeutic uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin is used commonly in the treatment from mild to moderate pain, including fever and migraines. Next, aspirin is combined with other non-steroidal anti-inflammatory drugs and opioid analgesics in the treatment of pain which is associated with cancer.&lt;br /&gt;
&lt;br /&gt;
==Veterinary uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin has been used in veterinary medicine to treat pain and arthritis, which can be applied to cats and dogs. But this is not recommended, as there are better medications though. Also, dogs would suffer from gastrointestinal side effects due to salicylate in aspirin.&lt;br /&gt;
&lt;br /&gt;
Moreover, horses can also use aspirin for the pain relief. Again, it is not frequently used because of its relatively short-lived analgesic effects. Also horses do suffer the gastrointestinal side effects once taking aspirin.&lt;br /&gt;
&lt;br /&gt;
Therefore it’s not suggested that aspirin can apply to the animals unless other circumstances.&lt;br /&gt;
&lt;br /&gt;
==Side effects==&lt;br /&gt;
&lt;br /&gt;
The main side effect of overtaking aspirin is gastrointestinal distress which includes stomach bleeding and ulcers. Due to its anticoagulant property, it causes an increase in bleeding for menstruating women. Moreover, high doses of aspirin will inhibit the synthesis of prothrombin that causes another side effect. And also aspirin is hard to control the symptoms of chickenpox or flu for those children under twelve years old.&lt;br /&gt;
&lt;br /&gt;
==Reference==&lt;br /&gt;
&lt;br /&gt;
http://en.wikipedia.org/wiki/Aspirin&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11276</id>
		<title>It07:Lactic acid</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11276"/>
		<updated>2007-11-19T14:32:48Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
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|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Lactic acid.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-hydroxypropanoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Milk acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| C[C@H](O)C(O)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-21-5 (L): 79-33-4 (D): 10326-41-7 (D/L): 598-82-3&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 90.08 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Acidity (pK&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;)&lt;br /&gt;
| 3.85&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 122&amp;amp;nbsp;°C@12mmHg&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| (L): 53&amp;amp;nbsp;°C (D): 53&amp;amp;nbsp;°C (D/L): 16.8&amp;amp;nbsp;°C&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Lactic acid, also known as milk acid, is a chemical compound which is very important in the biochemical process. It’s a carboxylic acid as shown in the template having a molecular formula C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. There’s a hydroxyl group next to the carboxyl group, which makes it becomes an alpha hydroxyl acid, known as AHA. When it is placed in the solution, the proton can be lost from the acidic group, generating the lactate ion CH3CH(OH)COO-. Furthermore, it’s hygroscopic as it’s miscible with either ethanol or water.&lt;br /&gt;
&lt;br /&gt;
There’s a chiral centre in the lactic acid which generates two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid. On the other hand, its mirror image, which is known as D-(-)-lactic acid or (R)-lactic acid. The L-(+)-Lactic acid is an important isomer in biology.&lt;br /&gt;
&lt;br /&gt;
Lactic acid is made by a process called fermentation which releases energy from carbohydrate without requiring any oxygen. Lectate is one of the maim components of Ringer&#039;s lactate or lactated Ringer’s solution in medicine. This intravenous liquid which transfers the liquid substances into the vein, consists of potassium and sodium cations, with also chloride and lactate anions. In order for the concentration to be isotonic comparing to human blood, this liquid is in the solution with distilled water. It’s often used as the fluid resucitation after lossing of blood by burn injury or a surgery.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
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&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Relationship between lacate and exercise==&lt;br /&gt;
&lt;br /&gt;
When performing some power-intensive exercises like sprinting, with a high demand of the energy, the lactate is generated a lot faster than the removal of it by the tissues. Thus the lactate concentration starts to rise. Due to the regeneration of nicotinamide adenine dinucleotide (NAD&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;), the energy production can be maintained and therefore the exercise can be continued. The increase in the lactate produced can be removed in several ways, e.g. by a process of gluconeogenesis in the liver to convert to glucose through the Cori cycle.&lt;br /&gt;
&lt;br /&gt;
==Lactic acid as a polymer==&lt;br /&gt;
&lt;br /&gt;
Lactic acid is commonly used as a monomer to produce polylactic acid (PLA) which is then turned to biodegradable plastic. The old conventional plastic made from petroleum oil is less applicable as there’s a higher emission of CO&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt; which causes global warming. Hence this biodegradable plastic is worth to substitute the conventional plastic.&lt;br /&gt;
&lt;br /&gt;
==Usage of lactic acid in foods==&lt;br /&gt;
&lt;br /&gt;
Normally lactic acis is found in some sour milk products like yogart, cottage cheese and kefir. In addition, lactic acis could also be found in different processed food. It can be either as a pH adjusting ingredient or as a preservative.&lt;br /&gt;
&lt;br /&gt;
==Reference==&lt;br /&gt;
1) http://en.wikipedia.org/wiki/Lactic_acid&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11266</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11266"/>
		<updated>2007-11-19T14:26:51Z</updated>

		<summary type="html">&lt;p&gt;Whc06: /* Overiew */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
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&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
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&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Adverse effect==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
1)	http://en.wikipedia.org/wiki/Salbutamol&lt;br /&gt;
&lt;br /&gt;
2)	http://www.salbutamol.com/&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Methylenedioxymethamphetamine&amp;diff=11209</id>
		<title>It07:Methylenedioxymethamphetamine</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Methylenedioxymethamphetamine&amp;diff=11209"/>
		<updated>2007-11-18T12:28:39Z</updated>

		<summary type="html">&lt;p&gt;Whc06: /* Methylenedioxymethamphetamine */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | Methylenedioxymethamphetamine &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:It07-Methylenedioxymethamphetamine.jpg]] &lt;br /&gt;
 &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| 3,4-methylenedioxy-N-methylamphetamine &lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| N-methyl 1-1-(3,4-methylenedioxyphenyl)-2-propanamine, MDMA, Ecstacy&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C11H15NO2 &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| CN[C@@H](C)CC1=CC(OCO2)=C2C=C1&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 193.24g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| White crystalline solid&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 69610-10-2&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| -144.4F  &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| 148 F&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| Neurotoxic &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| Amphetamine, MDEA, Methylenedioxymethcathinone, Paramethoxyamphetamine.&lt;br /&gt;
|- &lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
== Methylenedioxymethamphetamine ==&lt;br /&gt;
&lt;br /&gt;
Often known as MDMA or Ecstacy, 3,4-methylenedioxy-N-methylamphetamine is a semisynthetic empathogen-entactogen, an illegal drug that acts as a stimulant producing an psychedelic energizing effect, as well as distortions in time, perception and enhanced enjoyment of tactile experiences. MDMA exerts its primary effects on neurons in the brain that use the chemical serotonin to communicate with other neurons. Aside from recreational purposes, it is used as a tool to supplement various practices including meditation, psychonautics, and illicit psychedelic psychotherapy.&lt;br /&gt;
Research in animals indicates that MDMA is neurotoxic; whether or not this is also true in humans is currently an area of intense investigation. MDMA can also be dangerous to health and, on rare occasions, lethal.&lt;br /&gt;
&lt;br /&gt;
[[Image:Ecstacy-02.jpg]]&lt;br /&gt;
&amp;lt;ref&amp;gt;http://www.usdoj.gov/dea/photos/mdma/ecstacy-02.jpg&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;32488.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== History ==&lt;br /&gt;
&lt;br /&gt;
MDMA was first synthesized in 1912, soon after it was patented in Germany by the Merck Company. At that time it was not the subject of human research, but Merck stumbled across MDMA when they tried to synthesize Hydrastinin, a vasoconstrictive and styptic medicine. MDMA was an unplanned by-product of this synthesis. In the 1950s it was briefly researched by the U.S. Government as part of the CIA&#039;s and the Army&#039;s chemical warfare investigations into MDMA as a truth serum, which proved to be unsuitable. The first reported recreational use was in the 1960s, where it became known as the love drug. In the mid-70s, the psychedelic therapy community rediscovered it and psychiatrists and therapists began to use it to supplement psychotherapy. In the early 1980s, the drug began to be used recreationally, most notably in Dallas, under the name the street name &#039;Ecstasy&#039;. The non-medical and therapeutic use of MDMA was made illegal in the USA in 1985. Soon afterwards its use rapidly spread outside the United States, where it was widely used in the UK and other parts of Europe, becoming an integral part of the rave subculture and other psychedelic and dancefloor influenced music scenes.&amp;lt;ref&amp;gt;http://www.a1b2c3.com/drugs/x_01.htm&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Synthesis ==&lt;br /&gt;
&lt;br /&gt;
Reaction Overview:&lt;br /&gt;
The &#039;ketone&#039; approach is one of many synthesis schemes for the production of MDMA. This basic scheme is the oxidation of the plant oil &#039;safrole&#039; (1-allyl-3,4-methylenedioxybenzene) into a ketone (3,4-methylenedioxyphenyl-2-propanone), which is then condensed with methylamine and reduced to the final MDMA product.&lt;br /&gt;
&lt;br /&gt;
[[Image:Mdma_synthesis.JPG]]&lt;br /&gt;
&lt;br /&gt;
Step 1: Peroxyacid oxidation (requires isomerization of safrole). &lt;br /&gt;
&lt;br /&gt;
Step 2: Reversible imine formation, which reacts spontaneously when the ketone is added to a  solution of methylamine.&lt;br /&gt;
&lt;br /&gt;
Step 3: Reduction, permanently converts the imine to MDMA.&lt;br /&gt;
&amp;lt;ref&amp;gt;http://thedea.org/synthesis.html&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Effects on the Human Body ==&lt;br /&gt;
&lt;br /&gt;
The most common use of MDMA is for recreational purposes. Classed as a stimulant, the effects produced on the human body include euphoria, increased awareness of the senses, feelings of openness, empathy, heightened self-awareness and feeling of mental clarity. Tactile sensations are enhanced for some users resulting in physical contact with others more intense. ‘Alexander Shulgin stated that the single best use of MDMA was to facilitate more direct communication between people involved in significant emotional relationships.’ Physical effects on the body include sweaty palms, heavy sweating, increased heart rate, increased body temperature, and heightened touch sensations. &lt;br /&gt;
 	&lt;br /&gt;
Naturally there are many health risks involved in taking a stimulant such as MDMA. Physically these risks include hypertension, dehydration and hyperthermia. This is mostly due to the drug&#039;s stimulatory effects masking the body&#039;s normal sense of exhaustion and thirst.&lt;br /&gt;
MDMA is also neurotoxic which means it interferes with brain chemistry, sometimes permanently. The metabolism of MDMA leads to the lipid peroxidation of serotonergic neurons, thus interfering with the brain&#039;s ability to effectively use serotonin.&lt;br /&gt;
Psychologically, MDMA use often results in a rebound period of poor mood, often known as a ‘comedown’. Obviously this varies in length between different users but can often lead to lasting depression and anxiety in vulnerable users. The longer the time MDMA is active in the brain, the greater the neurotoxic damage to the brain and the greater the risk of short-term emotional problems. The more times MDMA is taken, the greater the risk of any long-term problems.&lt;br /&gt;
&lt;br /&gt;
===Short Term Effects===&lt;br /&gt;
In significantly high doses, MDMA can interfere with the body’s ability to regulate temperature, thus effecting homeostasis. On the very rare, but unpredictable occasions, this can possibly lead to a quick sharp increase in body&#039;s core temperature (leads to hyperthermia), resulting in failure in the following major organs; liver, kidney, and in cardiovascular system and the worst case scenario is death.&lt;br /&gt;
&lt;br /&gt;
MDMA is a drug that can unfortunately interfere with the body&#039;s metabolism of the drug and this can lead to potentially harmful levels, especially if the drug is repeatedly used in a short space of time.&lt;br /&gt;
&lt;br /&gt;
Users of MDMA can face many of the same risks/side effects as casual and frequent users of other stimulants; like cocaine and amphetamines. These typically include increases in heart rate and blood pressure, which is has significantly higher risk for people with either circulatory problems or heart disease, and other symptoms include muscle tension, involuntary teeth clenching, nausea, blurred vision, faintness, and chills or sweating.&lt;br /&gt;
&lt;br /&gt;
Almost two thirds of people who use MDMA report withdrawal symptoms, including fatigue, loss of appetite, depressed feelings, and trouble concentrating.&lt;br /&gt;
&lt;br /&gt;
===Long Term Effects===&lt;br /&gt;
&lt;br /&gt;
MDMA exposure can lead to long-term damage to the neurons in the brain that are involved in the following; mood, thinking, and judgment. There has been a study in nonhuman primates that has been found to show that exposure to MDMA for only 4 days had caused severe damage to serotonin nerve terminals that became apparent 6 to 7 years later. However,similar neurotoxicity in humans has not been definitively shown, but the wealth of all the animal research indicating MDMA’s damaging properties strongly suggests that MDMA an unsafe drug for human consumption.&amp;lt;ref&amp;gt;http://www.usdoj.gov/dea/concern/mdma.html&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Commonly used names==&lt;br /&gt;
&lt;br /&gt;
MDMA, Ecstasy, XTC, E, X, Beans, Adams, Hug Drug, Disco Biscuit. &amp;lt;ref&amp;gt;http://www.usdoj.gov/dea/concern/mdma.html&lt;br /&gt;
&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Legal Status ==&lt;br /&gt;
&lt;br /&gt;
MDMA is Class A in the UK, making it illegal to sell, buy, or possess without a license. This is typical of almost all countries around the world, but there are however a few countries including Canada and Belgium where possession is legal with a prescription or licence.&amp;lt;ref&amp;gt;http://www.erowid.org/chemicals/mdma/&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Spectroscopic Data ==&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;NMR Spectrum: 3,4-methylenedioxy-N-methylamphetamine&#039;&#039;&#039; &lt;br /&gt;
&lt;br /&gt;
[[Image:Mdma_nmr.JPG]]&lt;br /&gt;
&amp;lt;ref&amp;gt;http://www.rsc.org/delivery/_ArticleLinking/DisplayArticleForFree.cfm?doi=b201496n&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references/&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;jmol&amp;gt;&lt;br /&gt;
  &amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
     &amp;lt;title&amp;gt;MDMA&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;white&amp;lt;/color&amp;gt;&lt;br /&gt;
     &amp;lt;size&amp;gt;300&amp;lt;/size&amp;gt;&lt;br /&gt;
     &amp;lt;script&amp;gt;zoom 100; cpk -25;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
     &amp;lt;uploadedFileContents&amp;gt;Mdma3D.PDB&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
  &amp;lt;/jmolApplet&amp;gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:32488.pdb&amp;diff=11208</id>
		<title>File:32488.pdb</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:32488.pdb&amp;diff=11208"/>
		<updated>2007-11-18T12:27:45Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Phenethylamine&amp;diff=11207</id>
		<title>It07:Phenethylamine</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Phenethylamine&amp;diff=11207"/>
		<updated>2007-11-18T12:20:33Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==Phenethylamine==&lt;br /&gt;
Phenethylamine is an alkaloid that belongs to a class of molecules related to adrenalin. It occurs naturally in the human body due to its biosynthesis from the amino acid phenylalanine and can also be broken down in the body by the enzyme monoamine oxidase B. Phenethylamine derivatives are present in some citrus fruits and the compound itself is found in chocolate. The occurrence of migraine in some people after the consumption of chocolate has been associated with a build up of phenethylamine in the body due to a lack of the enzyme required to metabolise it.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Phenylamine.jpg|200px|Phenylamine]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| Phenethylamine&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Phenaethylamin, 2-Phenylethylamine, benzeneethanamine, beta-Phenylethylamine&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C8H11N&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| NCCc1ccccc1&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 121.18g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| {{{Appearance}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 60-04-0&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| 0.964g/cm³ &amp;lt;!-- ? g/cm³, solid / ? g/ml, liquid / ? g/l, gas --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| {{{Sol_Water}}} g/100 ml (25°C) &amp;lt;!--  at least put miscible with, not soluble in --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&amp;lt;!-- |- --&amp;gt;&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| {{{Mp}}} K &amp;lt;!-- (mention any decomposition) --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| 197-200°C&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Acidity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not an acid or a base.  If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKa}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Acid_dissociation_constant Basicity] (p&#039;&#039;K&#039;&#039;&amp;lt;sub&amp;gt;b&amp;lt;/sub&amp;gt;) &amp;lt;!-- omit if not a base. If several values, be clear --&amp;gt;&lt;br /&gt;
| {{{pKb}}}&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Specific_rotation Chiral rotation &amp;lt;nowiki&amp;gt;[α]&amp;lt;/nowiki&amp;gt;&amp;lt;sub&amp;gt;D&amp;lt;/sub&amp;gt;] &amp;lt;!-- (Only include this for chiral compounds, indicate direction/enantiomer combo if known) --&amp;gt;&lt;br /&gt;
| 1.533D&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| {{{Viscosity}}} [[Poise|cP]] at 25°C &amp;lt;!-- Liquids only, omit if data unavailable. You may use [[Pascal second|Pa.s]] if you prefer --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Structure&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Orbital_hybridisation Molecular shape] &amp;lt;!-- for simple covalent molecules (omit for most large molecules, ionics and complexes) --&amp;gt;&lt;br /&gt;
| {{{Mol_Shape}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Coordination_geometry Coordination&amp;lt;br /&amp;gt;geometry] &amp;lt;!-- for a metal complex or an ionic crystal, otherwise omit --&amp;gt;&lt;br /&gt;
| {{{Coordination}}} &amp;lt;!-- e.g. trigonal bipyramidal --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Crystal_structure Crystal structure] &amp;lt;!-- omit if not a solid --&amp;gt;&lt;br /&gt;
| {{{Crystal_Structure}}} &amp;lt;!-- e.g. [[triclinic]], [[monoclinic]], [[orthorhombic]], [[hexagonal]], [[rhombohedral|trigonal]], [[tetragonal]], [[cubic]], and mention &amp;quot;close packed&amp;quot; or similar.  You may also cite what class it belongs to, e.g. [[Cadmium_chloride#Crystal_structure|CdCl&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;]]  --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Dipole#Molecular_dipoles|Dipole moment]]&lt;br /&gt;
| {{{DM}}} [[Debye|D]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|External MSDS]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
| {{{Hazards}}} &amp;lt;!-- e.g. highly toxic, explosive, flammable, corrosive --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| {{{NFPA}}}&amp;lt;!-- {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| {{{Fp}}}°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: {{{R-S}}} &amp;lt;br /&amp;gt; [[List of S-phrases|S]]: ?&lt;br /&gt;
|-&lt;br /&gt;
| [[RTECS]] number&lt;br /&gt;
| SG8750000&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | [[{{PAGENAME}} (data page)|Supplementary data page]]&lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Structure and properties|Structure and&amp;lt;br /&amp;gt;properties]] &lt;br /&gt;
| [http://en.wikipedia.org/wiki/Refractive_index &#039;&#039;n&#039;&#039;], [http://en.wikipedia.org/wiki/Dielectric_constant ε&amp;lt;sub&amp;gt;r&amp;lt;/sub&amp;gt;], etc. &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Thermodynamic properties|Thermodynamic&amp;lt;br /&amp;gt;data]] &lt;br /&gt;
| Phase behaviour&amp;lt;br /&amp;gt;Solid, liquid, gas &lt;br /&gt;
|-&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Spectral data|Spectral data]]&lt;br /&gt;
| [[UV/VIS spectroscopy|UV]], [[Infrared spectroscopy|IR]], [[nuclear magnetic resonance spectroscopy|NMR]], [[Mass spectrometry|MS]]&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|anion]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Other_anion}}} &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Other [[Ion|cation]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Ohter_cation}}} &amp;lt;!-- Put in other oxidation states of same element e.g. [[iron(III) chloride]], also for related metals such as [[manganese(II) chloride]], [[cobalt(II) chloride]], ruthenium(III) chloride--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Related compounds &lt;br /&gt;
&amp;lt;!-- A miscellaneous heading - use for covalent inorganics;  e.g. for PCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; you would list PCl&amp;lt;sub&amp;gt;5&amp;lt;/sub&amp;gt;, POCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PF&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, PBr&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;, NCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; and AsCl&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. &lt;br /&gt;
Please omit if not applicable --&amp;gt;&lt;br /&gt;
| {{{Relative_Compounds}}}&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
{{Chem-Data_Structure}}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;32427.PDB&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:32427.PDB&amp;diff=11206</id>
		<title>File:32427.PDB</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:32427.PDB&amp;diff=11206"/>
		<updated>2007-11-18T12:14:53Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11205</id>
		<title>It07:Aspirin</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11205"/>
		<updated>2007-11-18T12:00:02Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Aspirin.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-acetoxybenzoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Acetylsalicylic acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;9&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| CC(OC1=C(C(O)=O)C=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-78-2&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 180.16 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Density&lt;br /&gt;
| 1.40gcm&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 140&amp;amp;nbsp;°C (284&amp;amp;nbsp;°F) (decomposes)&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| 138-140&amp;amp;nbsp;°C (280-284&amp;amp;nbsp;°F)&lt;br /&gt;
|-&lt;br /&gt;
| Solubility in water&lt;br /&gt;
| 10mg / ml (20&amp;amp;nbsp;°C)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Aspirin, also known as acetylsalicylic acid, is a salicylate drug which usually uses as an analgesic to relieve pains and minor aches, an antipyretic to reduce fever, or as an anti-inflammatory. Besides this, it also has the antiplatelet effect that causes “blood-thinning” to be used in long term. Aspirin can prevent the heart attack in low doses.&lt;br /&gt;
&lt;br /&gt;
Aspirin was the member of the class of drugs which is known as non-steroidal anti0inflammatory drugs (NSAIDs). Here not all of them are salicylates. But they all &lt;br /&gt;
have the similar effects.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;24847.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Synthesis==&lt;br /&gt;
&lt;br /&gt;
It’s classified as an esterification reaction for the synthesis of aspirin in which the alcohol group from the salicylic acid reacts with the acetic anhydride to form an ester.&lt;br /&gt;
&lt;br /&gt;
Generally, aspirin is synthesized via a two step process. First of all, the phenol that normally generated from coal tar, reacts with a sodium base to form a sodium phenolate. Under high pressure and temperature, it reacts with carbon dioxide to yield salicylate. Finally, it’s acidified to form salicylic acid. This process is called the Kolbe-Schmitt reaction.&lt;br /&gt;
&lt;br /&gt;
Secondly, the salicylic acid is then acetylated via an acetic anhydride, which yields aspirin and acetic acid as a side-product. As it’s hard for the extraction from an aqueous state, this reaction usually produces a low yield. Another method in getting higher yield is to acidify with phosphoric acid, followed by heating under reflux in 40-60 minutes.&lt;br /&gt;
&lt;br /&gt;
In addition, the original synthesis of aspirin from salicylic acid involves acetylation with acetyl chloride. Therefore hydrochloric acid will be formed as a by-product and it is very corrosive and environmentally hazardous. However in the second step above, salicylic acid can be acetylated with acetic anhydride which is a better acylating agent. Then acetic acid formed as the side-product doesn’t contain the harmful properties of the hydrochloric acid. Furthermore, the acetic acid can be recycled. So it’s much better to use acetic anhydride as an acetylating agent.&lt;br /&gt;
&lt;br /&gt;
In the synthesis, a smell of vinegar can be altered if a high concentration of aspirin is used. It is because aspirin could undergo autocatalysis in a moistened condition which then yields salicylic acid and acetic acid.&lt;br /&gt;
&lt;br /&gt;
[[Image:Reaction.JPG]]&lt;br /&gt;
&lt;br /&gt;
==Therapeutic uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin is used commonly in the treatment from mild to moderate pain, including fever and migraines. Next, aspirin is combined with other non-steroidal anti-inflammatory drugs and opioid analgesics in the treatment of pain which is associated with cancer.&lt;br /&gt;
&lt;br /&gt;
==Veterinary uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin has been used in veterinary medicine to treat pain and arthritis, which can be applied to cats and dogs. But this is not recommended, as there are better medications though. Also, dogs would suffer from gastrointestinal side effects due to salicylate in aspirin.&lt;br /&gt;
&lt;br /&gt;
Moreover, horses can also use aspirin for the pain relief. Again, it is not frequently used because of its relatively short-lived analgesic effects. Also horses do suffer the gastrointestinal side effects once taking aspirin.&lt;br /&gt;
&lt;br /&gt;
Therefore it’s not suggested that aspirin can apply to the animals unless other circumstances.&lt;br /&gt;
&lt;br /&gt;
==Side effects==&lt;br /&gt;
&lt;br /&gt;
The main side effect of overtaking aspirin is gastrointestinal distress which includes stomach bleeding and ulcers. Due to its anticoagulant property, it causes an increase in bleeding for menstruating women. Moreover, high doses of aspirin will inhibit the synthesis of prothrombin that causes another side effect. And also aspirin is hard to control the symptoms of chickenpox or flu for those children under twelve years old.&lt;br /&gt;
&lt;br /&gt;
==Reference==&lt;br /&gt;
&lt;br /&gt;
http://en.wikipedia.org/wiki/Aspirin&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11204</id>
		<title>It07:Aspirin</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11204"/>
		<updated>2007-11-18T11:59:06Z</updated>

		<summary type="html">&lt;p&gt;Whc06: /* Synthesis */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Aspirin.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-acetoxybenzoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Acetylsalicylic acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;9&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| CC(OC1=C(C(O)=O)C=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-78-2&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 180.16 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Density&lt;br /&gt;
| 1.40gcm&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 140&amp;amp;nbsp;°C (284&amp;amp;nbsp;°F) (decomposes)&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| 138-140&amp;amp;nbsp;°C (280-284&amp;amp;nbsp;°F)&lt;br /&gt;
|-&lt;br /&gt;
| Solubility in water&lt;br /&gt;
| 10mg / ml (20&amp;amp;nbsp;°C)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Aspirin, also known as acetylsalicylic acid, is a salicylate drug which usually uses as an analgesic to relieve pains and minor aches, an antipyretic to reduce fever, or as an anti-inflammatory. Besides this, it also has the antiplatelet effect that causes “blood-thinning” to be used in long term. Aspirin can prevent the heart attack in low doses.&lt;br /&gt;
&lt;br /&gt;
Aspirin was the member of the class of drugs which is known as non-steroidal anti0inflammatory drugs (NSAIDs). Here not all of them are salicylates. But they all &lt;br /&gt;
have the similar effects.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;24847.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Synthesis==&lt;br /&gt;
&lt;br /&gt;
It’s classified as an esterification reaction for the synthesis of aspirin in which the alcohol group from the salicylic acid reacts with the acetic anhydride to form an ester.&lt;br /&gt;
&lt;br /&gt;
Generally, aspirin is synthesized via a two step process. First of all, the phenol that normally generated from coal tar, reacts with a sodium base to form a sodium phenolate. Under high pressure and temperature, it reacts with carbon dioxide to yield salicylate. Finally, it’s acidified to form salicylic acid. This process is called the Kolbe-Schmitt reaction.&lt;br /&gt;
&lt;br /&gt;
Secondly, the salicylic acid is then acetylated via an acetic anhydride, which yields aspirin and acetic acid as a side-product. As it’s hard for the extraction from an aqueous state, this reaction usually produces a low yield. Another method in getting higher yield is to acidify with phosphoric acid, followed by heating under reflux in 40-60 minutes.&lt;br /&gt;
&lt;br /&gt;
In addition, the original synthesis of aspirin from salicylic acid involves acetylation with acetyl chloride. Therefore hydrochloric acid will be formed as a by-product and it is very corrosive and environmentally hazardous. However in the second step above, salicylic acid can be acetylated with acetic anhydride which is a better acylating agent. Then acetic acid formed as the side-product doesn’t contain the harmful properties of the hydrochloric acid. Furthermore, the acetic acid can be recycled. So it’s much better to use acetic anhydride as an acetylating agent.&lt;br /&gt;
&lt;br /&gt;
In the synthesis, a smell of vinegar can be altered if a high concentration of aspirin is used. It is because aspirin could undergo autocatalysis in a moistened condition which then yields salicylic acid and acetic acid.&lt;br /&gt;
&lt;br /&gt;
[[Image:Reaction.JPG]]&lt;br /&gt;
&lt;br /&gt;
==Therapeutic uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin is used commonly in the treatment from mild to moderate pain, including fever and migraines. Next, aspirin is combined with other non-steroidal anti-inflammatory drugs and opioid analgesics in the treatment of pain which is associated with cancer.&lt;br /&gt;
&lt;br /&gt;
==Veterinary uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin has been used in veterinary medicine to treat pain and arthritis, which can be applied to cats and dogs. But this is not recommended, as there are better medications though. Also, dogs would suffer from gastrointestinal side effects due to salicylate in aspirin.&lt;br /&gt;
&lt;br /&gt;
Moreover, horses can also use aspirin for the pain relief. Again, it is not frequently used because of its relatively short-lived analgesic effects. Also horses do suffer the gastrointestinal side effects once taking aspirin.&lt;br /&gt;
&lt;br /&gt;
Therefore it’s not suggested that aspirin can apply to the animals unless other circumstances.&lt;br /&gt;
&lt;br /&gt;
==Side effects==&lt;br /&gt;
&lt;br /&gt;
The main side effect of overtaking aspirin is gastrointestinal distress which includes stomach bleeding and ulcers. Due to its anticoagulant property, it causes an increase in bleeding for menstruating women. Moreover, high doses of aspirin will inhibit the synthesis of prothrombin that causes another side effect. And also aspirin is hard to control the symptoms of chickenpox or flu for those children under twelve years old.&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11203</id>
		<title>It07:Aspirin</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11203"/>
		<updated>2007-11-18T11:56:49Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Aspirin.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-acetoxybenzoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Acetylsalicylic acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;9&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| CC(OC1=C(C(O)=O)C=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-78-2&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 180.16 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Density&lt;br /&gt;
| 1.40gcm&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 140&amp;amp;nbsp;°C (284&amp;amp;nbsp;°F) (decomposes)&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| 138-140&amp;amp;nbsp;°C (280-284&amp;amp;nbsp;°F)&lt;br /&gt;
|-&lt;br /&gt;
| Solubility in water&lt;br /&gt;
| 10mg / ml (20&amp;amp;nbsp;°C)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Aspirin, also known as acetylsalicylic acid, is a salicylate drug which usually uses as an analgesic to relieve pains and minor aches, an antipyretic to reduce fever, or as an anti-inflammatory. Besides this, it also has the antiplatelet effect that causes “blood-thinning” to be used in long term. Aspirin can prevent the heart attack in low doses.&lt;br /&gt;
&lt;br /&gt;
Aspirin was the member of the class of drugs which is known as non-steroidal anti0inflammatory drugs (NSAIDs). Here not all of them are salicylates. But they all &lt;br /&gt;
have the similar effects.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;24847.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Synthesis==&lt;br /&gt;
&lt;br /&gt;
It’s classified as an esterification reaction for the synthesis of aspirin in which the alcohol group from the salicylic acid reacts with the acetic anhydride to form an ester.&lt;br /&gt;
&lt;br /&gt;
Generally, aspirin is synthesized via a two step process. First of all, the phenol that normally generated from coal tar, reacts with a sodium base to form a sodium phenolate. Under high pressure and temperature, it reacts with carbon dioxide to yield salicylate. Finally, it’s acidified to form salicylic acid. This process is called the Kolbe-Schmitt reaction.&lt;br /&gt;
&lt;br /&gt;
Secondly, the salicylic acid is then acetylated via an acetic anhydride, which yields aspirin and acetic acid as a side-product. As it’s hard for the extraction from an aqueous state, this reaction usually produces a low yield. Another method in getting higher yield is to acidify with phosphoric acid, followed by heating under reflux in 40-60 minutes.&lt;br /&gt;
&lt;br /&gt;
In addition, the original synthesis of aspirin from salicylic acid involves acetylation with acetyl chloride. Therefore hydrochloric acid will be formed as a by-product and it is very corrosive and environmentally hazardous. However in the second step above, salicylic acid can be acetylated with acetic anhydride which is a better acylating agent. Then acetic acid formed as the side-product doesn’t contain the harmful properties of the hydrochloric acid. Furthermore, the acetic acid can be recycled. So it’s much better to use acetic anhydride as an acetylating agent.&lt;br /&gt;
&lt;br /&gt;
In the synthesis, a smell of vinegar can be altered if a high concentration of aspirin is used. It is because aspirin could undergo autocatalysis in a moistened condition which then yields salicylic acid and acetic acid.&lt;br /&gt;
&lt;br /&gt;
==Therapeutic uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin is used commonly in the treatment from mild to moderate pain, including fever and migraines. Next, aspirin is combined with other non-steroidal anti-inflammatory drugs and opioid analgesics in the treatment of pain which is associated with cancer.&lt;br /&gt;
&lt;br /&gt;
==Veterinary uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin has been used in veterinary medicine to treat pain and arthritis, which can be applied to cats and dogs. But this is not recommended, as there are better medications though. Also, dogs would suffer from gastrointestinal side effects due to salicylate in aspirin.&lt;br /&gt;
&lt;br /&gt;
Moreover, horses can also use aspirin for the pain relief. Again, it is not frequently used because of its relatively short-lived analgesic effects. Also horses do suffer the gastrointestinal side effects once taking aspirin.&lt;br /&gt;
&lt;br /&gt;
Therefore it’s not suggested that aspirin can apply to the animals unless other circumstances.&lt;br /&gt;
&lt;br /&gt;
==Side effects==&lt;br /&gt;
&lt;br /&gt;
The main side effect of overtaking aspirin is gastrointestinal distress which includes stomach bleeding and ulcers. Due to its anticoagulant property, it causes an increase in bleeding for menstruating women. Moreover, high doses of aspirin will inhibit the synthesis of prothrombin that causes another side effect. And also aspirin is hard to control the symptoms of chickenpox or flu for those children under twelve years old.&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:24847.pdb&amp;diff=11202</id>
		<title>File:24847.pdb</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:24847.pdb&amp;diff=11202"/>
		<updated>2007-11-18T11:51:44Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Aspirin.JPG&amp;diff=11201</id>
		<title>File:Aspirin.JPG</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Aspirin.JPG&amp;diff=11201"/>
		<updated>2007-11-18T11:51:28Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11200</id>
		<title>It07:Aspirin</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Aspirin&amp;diff=11200"/>
		<updated>2007-11-18T11:51:10Z</updated>

		<summary type="html">&lt;p&gt;Whc06: New page: &amp;lt;noinclude&amp;gt; &amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[...&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Aspirin.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-acetoxybenzoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Acetylsalicylic acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;9&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;8&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;4&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| CC(OC1=C(C(O)=O)C=CC=C1)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-78-2&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 180.16 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Density&lt;br /&gt;
| 1.40gcm&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 140&amp;amp;nbsp;°C (284&amp;amp;nbsp;°F) (decomposes)&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| 138-140&amp;amp;nbsp;°C (280-284&amp;amp;nbsp;°F)&lt;br /&gt;
|-&lt;br /&gt;
| Solubility in water&lt;br /&gt;
| 10mg / ml (20&amp;amp;nbsp;°C)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Aspirin, also known as acetylsalicylic acid, is a salicylate drug which usually uses as an analgesic to relieve pains and minor aches, an antipyretic to reduce fever, or as an anti-inflammatory. Besides this, it also has the antiplatelet effect that causes “blood-thinning” to be used in long term. Aspirin can prevent the heart attack in low doses.&lt;br /&gt;
&lt;br /&gt;
Aspirin was the member of the class of drugs which is known as non-steroidal anti0inflammatory drugs (NSAIDs). Here not all of them are salicylates. But they all &lt;br /&gt;
have the similar effects.&lt;br /&gt;
&lt;br /&gt;
==Synthesis==&lt;br /&gt;
&lt;br /&gt;
It’s classified as an esterification reaction for the synthesis of aspirin in which the alcohol group from the salicylic acid reacts with the acetic anhydride to form an ester.&lt;br /&gt;
&lt;br /&gt;
Generally, aspirin is synthesized via a two step process. First of all, the phenol that normally generated from coal tar, reacts with a sodium base to form a sodium phenolate. Under high pressure and temperature, it reacts with carbon dioxide to yield salicylate. Finally, it’s acidified to form salicylic acid. This process is called the Kolbe-Schmitt reaction.&lt;br /&gt;
&lt;br /&gt;
Secondly, the salicylic acid is then acetylated via an acetic anhydride, which yields aspirin and acetic acid as a side-product. As it’s hard for the extraction from an aqueous state, this reaction usually produces a low yield. Another method in getting higher yield is to acidify with phosphoric acid, followed by heating under reflux in 40-60 minutes.&lt;br /&gt;
&lt;br /&gt;
In addition, the original synthesis of aspirin from salicylic acid involves acetylation with acetyl chloride. Therefore hydrochloric acid will be formed as a by-product and it is very corrosive and environmentally hazardous. However in the second step above, salicylic acid can be acetylated with acetic anhydride which is a better acylating agent. Then acetic acid formed as the side-product doesn’t contain the harmful properties of the hydrochloric acid. Furthermore, the acetic acid can be recycled. So it’s much better to use acetic anhydride as an acetylating agent.&lt;br /&gt;
&lt;br /&gt;
In the synthesis, a smell of vinegar can be altered if a high concentration of aspirin is used. It is because aspirin could undergo autocatalysis in a moistened condition which then yields salicylic acid and acetic acid.&lt;br /&gt;
&lt;br /&gt;
==Therapeutic uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin is used commonly in the treatment from mild to moderate pain, including fever and migraines. Next, aspirin is combined with other non-steroidal anti-inflammatory drugs and opioid analgesics in the treatment of pain which is associated with cancer.&lt;br /&gt;
&lt;br /&gt;
==Veterinary uses==&lt;br /&gt;
&lt;br /&gt;
Aspirin has been used in veterinary medicine to treat pain and arthritis, which can be applied to cats and dogs. But this is not recommended, as there are better medications though. Also, dogs would suffer from gastrointestinal side effects due to salicylate in aspirin.&lt;br /&gt;
&lt;br /&gt;
Moreover, horses can also use aspirin for the pain relief. Again, it is not frequently used because of its relatively short-lived analgesic effects. Also horses do suffer the gastrointestinal side effects once taking aspirin.&lt;br /&gt;
&lt;br /&gt;
Therefore it’s not suggested that aspirin can apply to the animals unless other circumstances.&lt;br /&gt;
&lt;br /&gt;
==Side effects==&lt;br /&gt;
&lt;br /&gt;
The main side effect of overtaking aspirin is gastrointestinal distress which includes stomach bleeding and ulcers. Due to its anticoagulant property, it causes an increase in bleeding for menstruating women. Moreover, high doses of aspirin will inhibit the synthesis of prothrombin that causes another side effect. And also aspirin is hard to control the symptoms of chickenpox or flu for those children under twelve years old.&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=11199</id>
		<title>It:projects</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=11199"/>
		<updated>2007-11-18T11:49:47Z</updated>

		<summary type="html">&lt;p&gt;Whc06: /* Supplemental  Project Page */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;__FORCETOC__&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;&#039;&#039;You MUST use the  Edit buttons on the right to edit this content.  Do NOT use the Edit button on the top of this page.&#039;&#039;&#039;&#039;&#039;&lt;br /&gt;
== Sandbox (Play-Pen) ==	 &lt;br /&gt;
		 &lt;br /&gt;
This is an area where you can play without worrying what you do. Enter it by pressing the [Edit] button &#039;&#039;&#039;on the right&#039;&#039;&#039; and &#039;&#039;&#039;not&#039;&#039;&#039; at the top. Go here for a [http://en.wikipedia.org/wiki/Wikipedia:Cheatsheet &#039;&#039;cheat sheet&#039;&#039;] summary of how to create a Wiki page.	 It&#039;s a free-for-all in here! Learn how to use a Wiki by coming here! PS This is how to do Greek:&amp;amp;alpha;, &amp;amp;beta; &amp;amp;Delta;, &amp;amp;delta;	 		 &lt;br /&gt;
Try copying/pasting some of the [http://www.ch.ic.ac.uk/local/it/lab1.html examples in the course work] into this page. See the effect by selecting &#039;&#039;&#039;Show Preview&#039;&#039;&#039;. Do not use &#039;&#039;&#039;Save Page&#039;&#039;&#039; so as to leave this area uncluttered for others.&lt;br /&gt;
----&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
|NEW: This demonstrates the use of  Jmol loading discrete molecule files (rather than having to paste them into the wiki page).  Upload the molecule file, and invoke it as shown here. Use it for eg loading large proteins etc.--[[User:Rzepa|Rzepa]] 16:07, 4 December 2006 (UTC) and --[[User:Rzepa|Rzepa]] 07:41, 16 October 2007 (BST) and  --[[User:Rzepa|Rzepa]] 15:56, 18 October 2007 (BST)&lt;br /&gt;
&lt;br /&gt;
If no rotatable molecule appears to the right, test that  [http://www.java.com/en/download/help/testvm.xml Java] is correctly functioning on your system.&lt;br /&gt;
&lt;br /&gt;
===References ===&lt;br /&gt;
This shows how citations&amp;lt;ref&amp;gt;Example of adding a citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; can be added to &lt;br /&gt;
text&amp;lt;ref&amp;gt;adding a further citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; to produce a nice effect.&lt;br /&gt;
&lt;br /&gt;
===Multiple uses of the same footnote ===&lt;br /&gt;
&lt;br /&gt;
The code for citing multiple quotes from the same source can be found [http://www.mediawiki.org/wiki/Extension:Cite/Cite.php here]. This stops the same reference being stated multiple times at the bottom of the page when you try to reference more than one item from the same source.&lt;br /&gt;
&lt;br /&gt;
=== Collected citations appear below here ===&lt;br /&gt;
&amp;lt;references /&amp;gt;--[[User:Rzepa|Rzepa]] 15:18, 25 October 2007 (BST)&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;yellow&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
== Main Project Page ==&lt;br /&gt;
&#039;&#039;&#039;Please do not edit this page itself&#039;&#039;&#039;.  Click on one of the titles to start editing.&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
! bgcolor=&amp;quot;cyan&amp;quot; |Project&amp;lt;br /&amp;gt; Number&lt;br /&gt;
! bgcolor=&amp;quot;cyan&amp;quot; |General Keywords&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |01&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Lignocaine|Lignocaine (used in dentistry as a &amp;quot;local&amp;quot;)]]&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |02&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |08&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |10&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |12&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |13&lt;br /&gt;
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== Cetirizine ==&lt;br /&gt;
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# [http://diberri.dyndns.org/wikipedia/html2wiki/ A HTML2Wiki Converter]&lt;br /&gt;
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[[Template:DOI]] and [[Template:Doi-inline]] are providea as (protected) templates for your use. Many other templates exist, often to be found on e.g. Wikipedia pages. You may decide one of these is of particular use, or of interest. If so, you can install it on the wiki here for you and others to use. Add below a line that looks like Template:Template-name, save, and click on the red text to create the new template. If you prefer the task of adding useful templates to that of adding information about molecules, then you will be given full credit for performing this valuable service for others! --Rzepa 14:41, 20 October 2006 (BST) &lt;br /&gt;
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[[Template:Chembox supplement]] - to be linked to from the supplementary section of the table in the template above, for usage see [[Template_talk:chembox_supplement|here]]&lt;br /&gt;
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[[Template:Chembox new]]&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11198</id>
		<title>It07:Lactic acid</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11198"/>
		<updated>2007-11-18T10:15:20Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Lactic acid.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-hydroxypropanoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Milk acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| C[C@H](O)C(O)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-21-5 (L): 79-33-4 (D): 10326-41-7 (D/L): 598-82-3&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 90.08 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Acidity (pK&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;)&lt;br /&gt;
| 3.85&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 122&amp;amp;nbsp;°C@12mmHg&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| (L): 53&amp;amp;nbsp;°C (D): 53&amp;amp;nbsp;°C (D/L): 16.8&amp;amp;nbsp;°C&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Lactic acid, also known as milk acid, is a chemical compound which is very important in the biochemical process. It’s a carboxylic acid as shown in the template having a molecular formula C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. There’s a hydroxyl group next to the carboxyl group, which makes it becomes an alpha hydroxyl acid, known as AHA. When it is placed in the solution, the proton can be lost from the acidic group, generating the lactate ion CH3CH(OH)COO-. Furthermore, it’s hygroscopic as it’s miscible with either ethanol or water.&lt;br /&gt;
&lt;br /&gt;
There’s a chiral centre in the lactic acid which generates two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid. On the other hand, its mirror image, which is known as D-(-)-lactic acid or (R)-lactic acid. The L-(+)-Lactic acid is an important isomer in biology.&lt;br /&gt;
&lt;br /&gt;
Lactic acid is made by a process called fermentation which releases energy from carbohydrate without requiring any oxygen. Lectate is one of the maim components of Ringer&#039;s lactate or lactated Ringer’s solution in medicine. This intravenous liquid which transfers the liquid substances into the vein, consists of potassium and sodium cations, with also chloride and lactate anions. In order for the concentration to be isotonic comparing to human blood, this liquid is in the solution with distilled water. It’s often used as the fluid resucitation after lossing of blood by burn injury or a surgery.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;5131.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Relationship between lacate and exercise==&lt;br /&gt;
&lt;br /&gt;
When performing some power-intensive exercises like sprinting, with a high demand of the energy, the lactate is generated a lot faster than the removal of it by the tissues. Thus the lactate concentration starts to rise. Due to the regeneration of nicotinamide adenine dinucleotide (NAD&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;), the energy production can be maintained and therefore the exercise can be continued. The increase in the lactate produced can be removed in several ways, e.g. by a process of gluconeogenesis in the liver to convert to glucose through the Cori cycle.&lt;br /&gt;
&lt;br /&gt;
==Lactic acid as a polymer==&lt;br /&gt;
&lt;br /&gt;
Lactic acid is commonly used as a monomer to produce polylactic acid (PLA) which is then turned to biodegradable plastic. The old conventional plastic made from petroleum oil is less applicable as there’s a higher emission of CO&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt; which causes global warming. Hence this biodegradable plastic is worth to substitute the conventional plastic.&lt;br /&gt;
&lt;br /&gt;
==Usage of lactic acid in foods==&lt;br /&gt;
&lt;br /&gt;
Normally lactic acis is found in some sour milk products like yogart, cottage cheese and kefir. In addition, lactic acis could also be found in different processed food. It can be either as a pH adjusting ingredient or as a preservative.&lt;br /&gt;
&lt;br /&gt;
==Reference==&lt;br /&gt;
1) http://en.wikipedia.org/wiki/Lactic_acid&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11197</id>
		<title>It07:Lactic acid</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11197"/>
		<updated>2007-11-18T10:12:56Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:lactic acid.jpg|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-hydroxypropanoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Milk acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| C[C@H](O)C(O)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-21-5 (L): 79-33-4 (D): 10326-41-7 (D/L): 598-82-3&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 90.08 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Acidity (pK&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;)&lt;br /&gt;
| 3.85&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 122&amp;amp;nbsp;°C@12mmHg&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| (L): 53&amp;amp;nbsp;°C (D): 53&amp;amp;nbsp;°C (D/L): 16.8&amp;amp;nbsp;°C&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Lactic acid, also known as milk acid, is a chemical compound which is very important in the biochemical process. It’s a carboxylic acid as shown in the template having a molecular formula C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. There’s a hydroxyl group next to the carboxyl group, which makes it becomes an alpha hydroxyl acid, known as AHA. When it is placed in the solution, the proton can be lost from the acidic group, generating the lactate ion CH3CH(OH)COO-. Furthermore, it’s hygroscopic as it’s miscible with either ethanol or water.&lt;br /&gt;
&lt;br /&gt;
There’s a chiral centre in the lactic acid which generates two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid. On the other hand, its mirror image, which is known as D-(-)-lactic acid or (R)-lactic acid. The L-(+)-Lactic acid is an important isomer in biology.&lt;br /&gt;
&lt;br /&gt;
Lactic acid is made by a process called fermentation which releases energy from carbohydrate without requiring any oxygen. Lectate is one of the maim components of Ringer&#039;s lactate or lactated Ringer’s solution in medicine. This intravenous liquid which transfers the liquid substances into the vein, consists of potassium and sodium cations, with also chloride and lactate anions. In order for the concentration to be isotonic comparing to human blood, this liquid is in the solution with distilled water. It’s often used as the fluid resucitation after lossing of blood by burn injury or a surgery.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;5131.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Relationship between lacate and exercise==&lt;br /&gt;
&lt;br /&gt;
When performing some power-intensive exercises like sprinting, with a high demand of the energy, the lactate is generated a lot faster than the removal of it by the tissues. Thus the lactate concentration starts to rise. Due to the regeneration of nicotinamide adenine dinucleotide (NAD&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;), the energy production can be maintained and therefore the exercise can be continued. The increase in the lactate produced can be removed in several ways, e.g. by a process of gluconeogenesis in the liver to convert to glucose through the Cori cycle.&lt;br /&gt;
&lt;br /&gt;
==Lactic acid as a polymer==&lt;br /&gt;
&lt;br /&gt;
Lactic acid is commonly used as a monomer to produce polylactic acid (PLA) which is then turned to biodegradable plastic. The old conventional plastic made from petroleum oil is less applicable as there’s a higher emission of CO&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt; which causes global warming. Hence this biodegradable plastic is worth to substitute the conventional plastic.&lt;br /&gt;
&lt;br /&gt;
==Usage of lactic acid in foods==&lt;br /&gt;
&lt;br /&gt;
Normally lactic acis is found in some sour milk products like yogart, cottage cheese and kefir. In addition, lactic acis could also be found in different processed food. It can be either as a pH adjusting ingredient or as a preservative.&lt;br /&gt;
&lt;br /&gt;
==Reference==&lt;br /&gt;
1) http://en.wikipedia.org/wiki/Lactic_acid&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Lactic_acid.jpg&amp;diff=11196</id>
		<title>File:Lactic acid.jpg</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Lactic_acid.jpg&amp;diff=11196"/>
		<updated>2007-11-18T10:04:46Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11195</id>
		<title>It07:Lactic acid</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Lactic_acid&amp;diff=11195"/>
		<updated>2007-11-18T10:04:34Z</updated>

		<summary type="html">&lt;p&gt;Whc06: New page: &amp;lt;noinclude&amp;gt; &amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[...&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:lactic acid.jpg|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| 2-hydroxypropanoic acid&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Milk acid&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| C[C@H](O)C(O)=O&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 50-21-5 (L): 79-33-4 (D): 10326-41-7 (D/L): 598-82-3&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 90.08 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Acidity (pK&amp;lt;sub&amp;gt;a&amp;lt;/sub&amp;gt;)&lt;br /&gt;
| 3.85&lt;br /&gt;
|-&lt;br /&gt;
| Boiling point&lt;br /&gt;
| 122&amp;amp;nbsp;°C@12mmHg&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| Melting point&lt;br /&gt;
| (L): 53&amp;amp;nbsp;°C (D): 53&amp;amp;nbsp;°C (D/L): 16.8&amp;amp;nbsp;°C&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
==Overview==&lt;br /&gt;
&lt;br /&gt;
Lactic acid, also known as milk acid, is a chemical compound which is very important in the biochemical process. It’s a carboxylic acid as shown in the template having a molecular formula C&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;. There’s a hydroxyl group next to the carboxyl group, which makes it becomes an alpha hydroxyl acid, known as AHA. When it is placed in the solution, the proton can be lost from the acidic group, generating the lactate ion CH3CH(OH)COO-. Furthermore, it’s hygroscopic as it’s miscible with either ethanol or water.&lt;br /&gt;
&lt;br /&gt;
There’s a chiral centre in the lactic acid which generates two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid. On the other hand, its mirror image, which is known as D-(-)-lactic acid or (R)-lactic acid. The L-(+)-Lactic acid is an important isomer in biology.&lt;br /&gt;
&lt;br /&gt;
Lactic acid is made by a process called fermentation which releases energy from carbohydrate without requiring any oxygen. Lectate is one of the maim components of Ringer&#039;s lactate or lactated Ringer’s solution in medicine. This intravenous liquid which transfers the liquid substances into the vein, consists of potassium and sodium cations, with also chloride and lactate anions. In order for the concentration to be isotonic comparing to human blood, this liquid is in the solution with distilled water. It’s often used as the fluid resucitation after lossing of blood by burn injury or a surgery.&lt;br /&gt;
&lt;br /&gt;
==Relationship between lacate and exercise==&lt;br /&gt;
&lt;br /&gt;
When performing some power-intensive exercises like sprinting, with a high demand of the energy, the lactate is generated a lot faster than the removal of it by the tissues. Thus the lactate concentration starts to rise. Due to the regeneration of nicotinamide adenine dinucleotide (NAD&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;), the energy production can be maintained and therefore the exercise can be continued. The increase in the lactate produced can be removed in several ways, e.g. by a process of gluconeogenesis in the liver to convert to glucose through the Cori cycle.&lt;br /&gt;
&lt;br /&gt;
==Lactic acid as a polymer==&lt;br /&gt;
&lt;br /&gt;
Lactic acid is commonly used as a monomer to produce polylactic acid (PLA) which is then turned to biodegradable plastic. The old conventional plastic made from petroleum oil is less applicable as there’s a higher emission of CO&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt; which causes global warming. Hence this biodegradable plastic is worth to substitute the conventional plastic.&lt;br /&gt;
&lt;br /&gt;
==Usage of lactic acid in foods&lt;br /&gt;
&lt;br /&gt;
Normally lactic acis is found in some sour milk products like yogart, cottage cheese and kefir. In addition, lactic acis could also be found in different processed food. It can be either as a pH adjusting ingredient or as a preservative.&lt;br /&gt;
&lt;br /&gt;
==Reference==&lt;br /&gt;
1) http://en.wikipedia.org/wiki/Lactic_acid&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:5131.pdb&amp;diff=11194</id>
		<title>File:5131.pdb</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:5131.pdb&amp;diff=11194"/>
		<updated>2007-11-18T10:01:04Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Lactic_acid.JPG&amp;diff=11193</id>
		<title>File:Lactic acid.JPG</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Lactic_acid.JPG&amp;diff=11193"/>
		<updated>2007-11-18T09:57:32Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=11192</id>
		<title>It:projects</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=11192"/>
		<updated>2007-11-18T09:52:58Z</updated>

		<summary type="html">&lt;p&gt;Whc06: /* Supplemental  Project Page */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;__FORCETOC__&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;&#039;&#039;You MUST use the  Edit buttons on the right to edit this content.  Do NOT use the Edit button on the top of this page.&#039;&#039;&#039;&#039;&#039;&lt;br /&gt;
== Sandbox (Play-Pen) ==	 &lt;br /&gt;
		 &lt;br /&gt;
This is an area where you can play without worrying what you do. Enter it by pressing the [Edit] button &#039;&#039;&#039;on the right&#039;&#039;&#039; and &#039;&#039;&#039;not&#039;&#039;&#039; at the top. Go here for a [http://en.wikipedia.org/wiki/Wikipedia:Cheatsheet &#039;&#039;cheat sheet&#039;&#039;] summary of how to create a Wiki page.	 It&#039;s a free-for-all in here! Learn how to use a Wiki by coming here! PS This is how to do Greek:&amp;amp;alpha;, &amp;amp;beta; &amp;amp;Delta;, &amp;amp;delta;	 		 &lt;br /&gt;
Try copying/pasting some of the [http://www.ch.ic.ac.uk/local/it/lab1.html examples in the course work] into this page. See the effect by selecting &#039;&#039;&#039;Show Preview&#039;&#039;&#039;. Do not use &#039;&#039;&#039;Save Page&#039;&#039;&#039; so as to leave this area uncluttered for others.&lt;br /&gt;
----&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
|NEW: This demonstrates the use of  Jmol loading discrete molecule files (rather than having to paste them into the wiki page).  Upload the molecule file, and invoke it as shown here. Use it for eg loading large proteins etc.--[[User:Rzepa|Rzepa]] 16:07, 4 December 2006 (UTC) and --[[User:Rzepa|Rzepa]] 07:41, 16 October 2007 (BST) and  --[[User:Rzepa|Rzepa]] 15:56, 18 October 2007 (BST)&lt;br /&gt;
&lt;br /&gt;
If no rotatable molecule appears to the right, test that  [http://www.java.com/en/download/help/testvm.xml Java] is correctly functioning on your system.&lt;br /&gt;
&lt;br /&gt;
===References ===&lt;br /&gt;
This shows how citations&amp;lt;ref&amp;gt;Example of adding a citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; can be added to &lt;br /&gt;
text&amp;lt;ref&amp;gt;adding a further citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; to produce a nice effect.&lt;br /&gt;
&lt;br /&gt;
===Multiple uses of the same footnote ===&lt;br /&gt;
&lt;br /&gt;
The code for citing multiple quotes from the same source can be found [http://www.mediawiki.org/wiki/Extension:Cite/Cite.php here]. This stops the same reference being stated multiple times at the bottom of the page when you try to reference more than one item from the same source.&lt;br /&gt;
&lt;br /&gt;
=== Collected citations appear below here ===&lt;br /&gt;
&amp;lt;references /&amp;gt;--[[User:Rzepa|Rzepa]] 15:18, 25 October 2007 (BST)&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;yellow&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |01&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |12&lt;br /&gt;
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| bgcolor=&amp;quot;#CCFF00&amp;quot; |15&lt;br /&gt;
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#[[it07:Salbutamol|Salbutamol]]&lt;br /&gt;
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&lt;br /&gt;
== Cetirizine ==&lt;br /&gt;
Utilities have been written to help the conversion of material from HTML.&lt;br /&gt;
# [http://diberri.dyndns.org/wikipedia/html2wiki/ A HTML2Wiki Converter]&lt;br /&gt;
----&lt;br /&gt;
&lt;br /&gt;
== Wiki Templates ==&lt;br /&gt;
&lt;br /&gt;
[[Template:DOI]] and [[Template:Doi-inline]] are providea as (protected) templates for your use. Many other templates exist, often to be found on e.g. Wikipedia pages. You may decide one of these is of particular use, or of interest. If so, you can install it on the wiki here for you and others to use. Add below a line that looks like Template:Template-name, save, and click on the red text to create the new template. If you prefer the task of adding useful templates to that of adding information about molecules, then you will be given full credit for performing this valuable service for others! --Rzepa 14:41, 20 October 2006 (BST) &lt;br /&gt;
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[[Template:Chem-Data]]&lt;br /&gt;
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[[Template:Drug-Box]] - For pharmaceutical drugs just copy variable names and code generates tables&lt;br /&gt;
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[[Template:Chembox supplement]] - to be linked to from the supplementary section of the table in the template above, for usage see [[Template_talk:chembox_supplement|here]]&lt;br /&gt;
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[[Template:Chembox new]]&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11191</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11191"/>
		<updated>2007-11-18T09:50:55Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Adverse effect==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
1)	http://en.wikipedia.org/wiki/Salbutamol&lt;br /&gt;
&lt;br /&gt;
2)	http://www.salbutamol.com/&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11190</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11190"/>
		<updated>2007-11-18T09:49:41Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31002.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Adverse effect==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
1)	http://en.wikipedia.org/wiki/Salbutamol&lt;br /&gt;
&lt;br /&gt;
2)	http://www.salbutamol.com/&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:31002.pdb&amp;diff=11189</id>
		<title>File:31002.pdb</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:31002.pdb&amp;diff=11189"/>
		<updated>2007-11-18T09:46:24Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11188</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11188"/>
		<updated>2007-11-18T09:45:35Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Adverse effect==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
1)	http://en.wikipedia.org/wiki/Salbutamol&lt;br /&gt;
&lt;br /&gt;
2)	http://www.salbutamol.com/&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11187</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11187"/>
		<updated>2007-11-16T16:49:04Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Adverse effect==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11186</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11186"/>
		<updated>2007-11-16T16:48:24Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β&amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt;-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Adverse effect==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11185</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11185"/>
		<updated>2007-11-16T16:41:59Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
•  Acute asthma&lt;br /&gt;
&lt;br /&gt;
•  Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
•  Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
•  Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
•  Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
•  Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
•  Airomir&lt;br /&gt;
&lt;br /&gt;
•  Asthalin&lt;br /&gt;
&lt;br /&gt;
•  Asmol&lt;br /&gt;
&lt;br /&gt;
•  Buventol&lt;br /&gt;
&lt;br /&gt;
•  Proventil&lt;br /&gt;
&lt;br /&gt;
•  Salamol&lt;br /&gt;
&lt;br /&gt;
•  Sultanol&lt;br /&gt;
&lt;br /&gt;
•  Ventolin&lt;br /&gt;
&lt;br /&gt;
•  Volmax&lt;br /&gt;
&lt;br /&gt;
==Overdose==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
•  Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
•  Headache&lt;br /&gt;
&lt;br /&gt;
•  Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
•  Nausea&lt;br /&gt;
&lt;br /&gt;
•  Seizures&lt;br /&gt;
&lt;br /&gt;
•  Tremor&lt;br /&gt;
&lt;br /&gt;
•  Vomiting&lt;br /&gt;
&lt;br /&gt;
•  Weakness&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11184</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11184"/>
		<updated>2007-11-16T16:27:58Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
−Acute asthma&lt;br /&gt;
&lt;br /&gt;
−Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
−Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
−Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
−Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
−Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
−Airomir&lt;br /&gt;
&lt;br /&gt;
−Asthalin&lt;br /&gt;
&lt;br /&gt;
−Asmol&lt;br /&gt;
&lt;br /&gt;
−Buventol&lt;br /&gt;
&lt;br /&gt;
−Proventil&lt;br /&gt;
&lt;br /&gt;
−Salamol&lt;br /&gt;
&lt;br /&gt;
−Sultanol&lt;br /&gt;
&lt;br /&gt;
−Ventolin&lt;br /&gt;
&lt;br /&gt;
−Volmax&lt;br /&gt;
&lt;br /&gt;
==Overdose==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
−Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
−Headache&lt;br /&gt;
&lt;br /&gt;
−Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
−Nausea&lt;br /&gt;
&lt;br /&gt;
−Seizures&lt;br /&gt;
&lt;br /&gt;
−Tremor&lt;br /&gt;
&lt;br /&gt;
−Vomiting&lt;br /&gt;
&lt;br /&gt;
−Weakness&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11183</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11183"/>
		<updated>2007-11-16T16:20:48Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
−Acute asthma&lt;br /&gt;
&lt;br /&gt;
−Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
−Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
−Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
−Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
−Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Overdose==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
−Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
−Headache&lt;br /&gt;
&lt;br /&gt;
−Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
−Nausea&lt;br /&gt;
&lt;br /&gt;
−Seizures&lt;br /&gt;
&lt;br /&gt;
−Tremor&lt;br /&gt;
&lt;br /&gt;
−Vomiting&lt;br /&gt;
&lt;br /&gt;
−Weakness&lt;br /&gt;
&lt;br /&gt;
==Brand names==&lt;br /&gt;
In general, salbutamol is usually sold under the brand names as following:&lt;br /&gt;
&lt;br /&gt;
−Airomir&lt;br /&gt;
&lt;br /&gt;
−Asthalin&lt;br /&gt;
&lt;br /&gt;
−Asmol&lt;br /&gt;
&lt;br /&gt;
−Buventol&lt;br /&gt;
&lt;br /&gt;
−Proventil&lt;br /&gt;
&lt;br /&gt;
−Salamol&lt;br /&gt;
&lt;br /&gt;
−Sultanol&lt;br /&gt;
&lt;br /&gt;
−Ventolin&lt;br /&gt;
&lt;br /&gt;
−Volmax&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11182</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11182"/>
		<updated>2007-11-16T16:12:49Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.JPG|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
−Acute asthma&lt;br /&gt;
&lt;br /&gt;
−Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
−Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
−Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
−Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
−Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Overdose==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
−Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
−Headache&lt;br /&gt;
&lt;br /&gt;
−Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
−Nausea&lt;br /&gt;
&lt;br /&gt;
−Seizures&lt;br /&gt;
&lt;br /&gt;
−Tremor&lt;br /&gt;
&lt;br /&gt;
−Vomiting&lt;br /&gt;
&lt;br /&gt;
−Weakness&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11181</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11181"/>
		<updated>2007-11-16T16:02:02Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
−Acute asthma&lt;br /&gt;
&lt;br /&gt;
−Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
−Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
−Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
−Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
−Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;br /&gt;
&lt;br /&gt;
==Overdose==&lt;br /&gt;
Symtoms of a salbutamol overdose:&lt;br /&gt;
&lt;br /&gt;
−Angina or chet pain&lt;br /&gt;
&lt;br /&gt;
−Headache&lt;br /&gt;
&lt;br /&gt;
−Irregular heartbeats or a fluttering heart&lt;br /&gt;
&lt;br /&gt;
−Nausea&lt;br /&gt;
&lt;br /&gt;
−Seizures&lt;br /&gt;
&lt;br /&gt;
−Tremor&lt;br /&gt;
&lt;br /&gt;
−Vomiting&lt;br /&gt;
&lt;br /&gt;
−Weakness&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11180</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11180"/>
		<updated>2007-11-16T15:59:17Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
&lt;br /&gt;
−Acute asthma&lt;br /&gt;
&lt;br /&gt;
−Prevention of exercise-induced bronchospasm&lt;br /&gt;
&lt;br /&gt;
−Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
&lt;br /&gt;
−Treat high potassium levels in patients with kidney failure&lt;br /&gt;
&lt;br /&gt;
−Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
&lt;br /&gt;
−Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11179</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11179"/>
		<updated>2007-11-16T15:52:48Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
Acute asthma&lt;br /&gt;
Prevention of exercise-induced bronchospasm&lt;br /&gt;
Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
Treat high potassium levels in patients with kidney failure&lt;br /&gt;
Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11178</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11178"/>
		<updated>2007-11-16T15:49:41Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:taxol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| [http://en.wikipedia.org/wiki/IUPAC Systematic name]&lt;br /&gt;
| 2,4,6,8,10-pentamethylcyclopentasiloxane &lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Cyclic pentamer, D5&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_formula Molecular formula]&lt;br /&gt;
| C5H20O5Si5 &lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Chemical_file_format SMILES] &amp;lt;!-- mostly for organic compounds, omit otherwise --&amp;gt;&lt;br /&gt;
| C[SiH]1O[SiH](C)O[SiH](C)O[SiH](C)O[SiH](C)O1&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Molar_mass Molar mass]&lt;br /&gt;
| 370.77 g/mol&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| Clear, nearly odorless liquid&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/CAS_registry_number CAS number]&lt;br /&gt;
| 541-02-6&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Density Density] &amp;amp; [http://en.wikipedia.org/wiki/Phase_%28matter%29 phase]&lt;br /&gt;
| 0.958 g/cm³, liquid&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Solubility Solubility in water]&lt;br /&gt;
| Insoluble&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
-44°C (229 K)&lt;br /&gt;
&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Melting_point Melting point]&lt;br /&gt;
| -44°C (229 K)&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Boiling_point Boiling point]&lt;br /&gt;
| 90°C at 10 mmHg (363 K)&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| [http://en.wikipedia.org/wiki/Viscosity Viscosity]&lt;br /&gt;
| 3.74 cP at ?°C&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Hazards &amp;lt;!--  Summary only- MSDS entry provides more complete information --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Material safety data sheet|MSDS]]&lt;br /&gt;
| [[{{PAGENAME}} (data page)#Material Safety Data Sheet|MSDS-Cyclo-2245.pdf]] &amp;lt;!-- please replace with proper link--&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| Main [[Worker safety and health|hazard]]s&lt;br /&gt;
|Flammable, irritant&lt;br /&gt;
|-&lt;br /&gt;
| [[NFPA 704]]&lt;br /&gt;
| 75px-NFPA_704_svg {{NFPA 704 | Health=4 | Flammability=4 | Reactivity=4 | Other=OX }} These are set on &amp;quot;very dangerous&amp;quot; as default- adjust according to actual values --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| [[Flash point]]&lt;br /&gt;
| 76°C&lt;br /&gt;
|-&lt;br /&gt;
| [[Risk and Safety Statements|R/S statement]]&lt;br /&gt;
| [[List of R-phrases|R]]: 36, 37, 38&lt;br /&gt;
|-&lt;br /&gt;
| [[List of R-phrases|S]]: 23, 24, 25&lt;br /&gt;
|-[[RTECS]] number&lt;br /&gt;
| GY5945200&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
! {{chembox header}} | Related compounds&lt;br /&gt;
|-&lt;br /&gt;
| Other [[related organosilican compounds]]s &amp;lt;!-- please omit if not applicable --&amp;gt;&lt;br /&gt;
| silicon carbide, tetramethylsilane, silabenzene &amp;lt;!-- Put in related anions e.g, iron(II) fluoride &amp;amp; iron(II) bromide if compound is iron(II) chloride --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Cyclopentasiloxane&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;black&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;400&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 90; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;31736.pdb&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt; &lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
Acute asthma&lt;br /&gt;
Prevention of exercise-induced bronchospasm&lt;br /&gt;
Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
Treat high potassium levels in patients with kidney failure&lt;br /&gt;
Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:31736.pdb&amp;diff=11177</id>
		<title>File:31736.pdb</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:31736.pdb&amp;diff=11177"/>
		<updated>2007-11-16T15:45:41Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11176</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11176"/>
		<updated>2007-11-16T15:42:23Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;br /&gt;
==Overiew==&lt;br /&gt;
Salbutamol (INN), also known as albuterol, is a short-acting β2-adrenergic receptor agonist which is used to deal with bronchospasms with symptoms of coughing, wheezing and shortness of breath, which are associated with lung-related problems like asthma, bronchitis and chronic obstructive pulmonary disease (COPD).&lt;br /&gt;
&lt;br /&gt;
The salbutamol works by relaxing the muscles and the air passages in the lungs. Therefore air can flow into them much more freely to improve breathing.&lt;br /&gt;
&lt;br /&gt;
==Clinical use==&lt;br /&gt;
Other uses for this medicine:&lt;br /&gt;
Acute asthma&lt;br /&gt;
Prevention of exercise-induced bronchospasm&lt;br /&gt;
Hyperkalaemia, especially for those patients with renal failure&lt;br /&gt;
Treat high potassium levels in patients with kidney failure&lt;br /&gt;
Improve muscle paralysis in patients having a condition that causes occasional paralysis&lt;br /&gt;
Used as a tocolytic to relax the uterine smooth muscel which delays the premature labour&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Salbutamol.JPG&amp;diff=11175</id>
		<title>File:Salbutamol.JPG</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Salbutamol.JPG&amp;diff=11175"/>
		<updated>2007-11-16T15:27:53Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=File:Salbutamol.bmp&amp;diff=11174</id>
		<title>File:Salbutamol.bmp</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=File:Salbutamol.bmp&amp;diff=11174"/>
		<updated>2007-11-16T15:25:03Z</updated>

		<summary type="html">&lt;p&gt;Whc06: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11173</id>
		<title>It07:Salbutamol</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It07:Salbutamol&amp;diff=11173"/>
		<updated>2007-11-16T15:24:34Z</updated>

		<summary type="html">&lt;p&gt;Whc06: New page: &amp;lt;noinclude&amp;gt; &amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[...&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;noinclude&amp;gt;&lt;br /&gt;
&amp;lt;!-- This template has been defined after elaborate discussion in the Chemicals Wikiproject. Please do not add, deleted or otherwise change it unless after due discussion in [[wikipedia talk:WikiProject Chemicals]] --&amp;gt;&lt;br /&gt;
&amp;lt;/noinclude&amp;gt;{| class=&amp;quot;toccolours&amp;quot; border=&amp;quot;1&amp;quot; style=&amp;quot;float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse; width: 280px&amp;quot;&lt;br /&gt;
! {{chembox header}} | {{PAGENAME}} &amp;lt;!-- replace if not identical with the article name --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
| align=&amp;quot;center&amp;quot; colspan=&amp;quot;2&amp;quot; bgcolor=&amp;quot;#ffffff&amp;quot; | [[Image:Salbutamol.png|200px|{{PAGENAME}}]] &amp;lt;!-- replace if not identical with the pagename --&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | General&lt;br /&gt;
|- &lt;br /&gt;
| IUPAC Systematic name&lt;br /&gt;
| (±)alpha1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha&#039;-diol&lt;br /&gt;
|-&lt;br /&gt;
| Other names&lt;br /&gt;
| Albuterol&lt;br /&gt;
|-&lt;br /&gt;
| Molecular formula&lt;br /&gt;
| C&amp;lt;sub&amp;gt;13&amp;lt;/sub&amp;gt;H&amp;lt;sub&amp;gt;21&amp;lt;/sub&amp;gt;NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; &lt;br /&gt;
|-&lt;br /&gt;
| Composition&lt;br /&gt;
|C (65.25%) H( 8.84%) N (5.85%) O (20.06%)&lt;br /&gt;
|-&lt;br /&gt;
| SMILES&lt;br /&gt;
| OC1=CC=C(C(O)CNC(C)(C)C)C=C1CO&lt;br /&gt;
|-&lt;br /&gt;
| CAS number&lt;br /&gt;
| 18559-94-9&lt;br /&gt;
|-&lt;br /&gt;
| Molar mass&lt;br /&gt;
| 239.31 gmol-1&lt;br /&gt;
|-&lt;br /&gt;
| Appearance&lt;br /&gt;
| A white or almost white, crystalline powder. Clear solution in methanol, very pale clear yellow solution.&lt;br /&gt;
|-&lt;br /&gt;
! {{chembox header}} | Properties&lt;br /&gt;
|-&lt;br /&gt;
| Solubility&lt;br /&gt;
| Sparingly soluble in water; soluble in ethanol (96%); slightly soluble in ether.&lt;br /&gt;
|-&lt;br /&gt;
&amp;lt;!-- | Other solvents e.g. [[ethanol]], [[acetone]] --&amp;gt;&lt;br /&gt;
&amp;lt;!-- | solubility info on other solvents --&amp;gt;&lt;br /&gt;
&lt;br /&gt;
| Melting point&lt;br /&gt;
| 157-158&amp;amp;nbsp;°C (with decomposition)&lt;br /&gt;
|-&lt;br /&gt;
| {{chembox header}} | &amp;lt;small&amp;gt;Except where noted otherwise, data are given for&amp;lt;br /&amp;gt; materials in their [[standard state|standard state (at 25&amp;amp;nbsp;°C, 100&amp;amp;nbsp;kPa)]]&amp;lt;br /&amp;gt;[[wikipedia:Chemical infobox|Infobox disclaimer and references]]&amp;lt;/small&amp;gt;&lt;br /&gt;
|-&lt;br /&gt;
|}&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
	<entry>
		<id>https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=11161</id>
		<title>It:projects</title>
		<link rel="alternate" type="text/html" href="https://chemwiki.ch.ic.ac.uk/index.php?title=It:projects&amp;diff=11161"/>
		<updated>2007-11-16T14:28:19Z</updated>

		<summary type="html">&lt;p&gt;Whc06: /* Supplemental  Project Page */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;__FORCETOC__&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;&#039;&#039;You MUST use the  Edit buttons on the right to edit this content.  Do NOT use the Edit button on the top of this page.&#039;&#039;&#039;&#039;&#039;&lt;br /&gt;
== Sandbox (Play-Pen) ==	 &lt;br /&gt;
		 &lt;br /&gt;
This is an area where you can play without worrying what you do. Enter it by pressing the [Edit] button &#039;&#039;&#039;on the right&#039;&#039;&#039; and &#039;&#039;&#039;not&#039;&#039;&#039; at the top. Go here for a [http://en.wikipedia.org/wiki/Wikipedia:Cheatsheet &#039;&#039;cheat sheet&#039;&#039;] summary of how to create a Wiki page.	 It&#039;s a free-for-all in here! Learn how to use a Wiki by coming here! PS This is how to do Greek:&amp;amp;alpha;, &amp;amp;beta; &amp;amp;Delta;, &amp;amp;delta;	 		 &lt;br /&gt;
Try copying/pasting some of the [http://www.ch.ic.ac.uk/local/it/lab1.html examples in the course work] into this page. See the effect by selecting &#039;&#039;&#039;Show Preview&#039;&#039;&#039;. Do not use &#039;&#039;&#039;Save Page&#039;&#039;&#039; so as to leave this area uncluttered for others.&lt;br /&gt;
----&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
|NEW: This demonstrates the use of  Jmol loading discrete molecule files (rather than having to paste them into the wiki page).  Upload the molecule file, and invoke it as shown here. Use it for eg loading large proteins etc.--[[User:Rzepa|Rzepa]] 16:07, 4 December 2006 (UTC) and --[[User:Rzepa|Rzepa]] 07:41, 16 October 2007 (BST) and  --[[User:Rzepa|Rzepa]] 15:56, 18 October 2007 (BST)&lt;br /&gt;
&lt;br /&gt;
If no rotatable molecule appears to the right, test that  [http://www.java.com/en/download/help/testvm.xml Java] is correctly functioning on your system.&lt;br /&gt;
&lt;br /&gt;
===References ===&lt;br /&gt;
This shows how citations&amp;lt;ref&amp;gt;Example of adding a citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; can be added to &lt;br /&gt;
text&amp;lt;ref&amp;gt;adding a further citation {{DOI|10.1021/ja9825332}}&amp;lt;/ref&amp;gt; to produce a nice effect.&lt;br /&gt;
&lt;br /&gt;
===Multiple uses of the same footnote ===&lt;br /&gt;
&lt;br /&gt;
The code for citing multiple quotes from the same source can be found [http://www.mediawiki.org/wiki/Extension:Cite/Cite.php here]. This stops the same reference being stated multiple times at the bottom of the page when you try to reference more than one item from the same source.&lt;br /&gt;
&lt;br /&gt;
=== Collected citations appear below here ===&lt;br /&gt;
&amp;lt;references /&amp;gt;--[[User:Rzepa|Rzepa]] 15:18, 25 October 2007 (BST)&lt;br /&gt;
|&amp;lt;jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;title&amp;gt;Pentahelicene&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;yellow&amp;lt;/color&amp;gt;&amp;lt;size&amp;gt;200&amp;lt;/size&amp;gt;&lt;br /&gt;
&amp;lt;script&amp;gt;zoom 80; cpk on;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;&amp;lt;/script&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;Pentahelicene.mol&amp;lt;/uploadedFileContents&amp;gt;&lt;br /&gt;
&amp;lt;/jmolApplet&amp;gt;&lt;br /&gt;
&amp;lt;jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Start spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin on&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;item&amp;gt;&amp;lt;text&amp;gt;Stop spinning&amp;lt;/text&amp;gt;&amp;lt;script&amp;gt;spin off&amp;lt;/script&amp;gt;&amp;lt;/item&amp;gt;&lt;br /&gt;
&amp;lt;menuHeight&amp;gt;-1&amp;lt;/menuHeight&amp;gt;&lt;br /&gt;
&amp;lt;/jmolMenu&amp;gt;&lt;br /&gt;
&amp;lt;jmolButton&amp;gt;&lt;br /&gt;
    &amp;lt;script&amp;gt;console&amp;lt;/script&amp;gt;&lt;br /&gt;
    &amp;lt;text&amp;gt;open a console window&amp;lt;/text&amp;gt;&lt;br /&gt;
&amp;lt;/jmolButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
&amp;lt;jmol&amp;gt;&amp;lt;jmolAppletButton&amp;gt;&amp;lt;title&amp;gt;Show CIYSIM.cif in popup window&amp;lt;/title&amp;gt;&amp;lt;color&amp;gt;cyan&amp;lt;/color&amp;gt;&lt;br /&gt;
&amp;lt;uploadedFileContents&amp;gt;CIYSIM.cif&amp;lt;/uploadedFileContents&amp;gt;&amp;lt;/jmolAppletButton&amp;gt;&lt;br /&gt;
&amp;lt;/jmol&amp;gt;&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
== Main Project Page ==&lt;br /&gt;
&#039;&#039;&#039;Please do not edit this page itself&#039;&#039;&#039;.  Click on one of the titles to start editing.&lt;br /&gt;
{| summary=&amp;quot;CIT Project  Titles&amp;quot; border=&amp;quot;1&amp;quot;&lt;br /&gt;
! bgcolor=&amp;quot;cyan&amp;quot; |Project&amp;lt;br /&amp;gt; Number&lt;br /&gt;
! bgcolor=&amp;quot;cyan&amp;quot; |General Keywords&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |01&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Lignocaine|Lignocaine (used in dentistry as a &amp;quot;local&amp;quot;)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |02&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Piperine|Piperine (active ingredient of both black and white pepper)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |03&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Rapamycin|Rapamycin (prevents transplant rejection)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |04&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Gossypol|Gossypol (male birth control)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |05&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Gentamycin|Gentamicin A (aminoglycoside antibiotic)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |06&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Herceptin|Herceptin (topical anticancer drug)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |07&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Gingerone|Zingerone (the characteristic smell of ginger)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |08&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Sucralose|Sucralose (non-metabolizable sweetening agent)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |09&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Bufotoxin|Bufotoxin (active component of the toad &#039;&#039;Bufo vulgaris&#039;&#039;)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |10&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Roaccutane|Roaccutane (treatment for severe acne)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |11&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Sibutramine|Sibutramine (appetite suppresor)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |12&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Anandamide|Anandamide (the &amp;quot;feel-good&amp;quot; factor in chocolate)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |13&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:h3nbh3|Ammonia-borane: H&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;N-BH&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; (Hydrogen storage molecule?)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |14&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Methoxsalen|Methoxsalen (Treatment of psoriasis)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |15&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; | [[it07:Hycocine|Hyoscine (From Mandrake and Witches Henbane, pre-med before surgery)]]&lt;br /&gt;
|-&lt;br /&gt;
| bgcolor=&amp;quot;#CCFF00&amp;quot; |16&lt;br /&gt;
| bgcolor=&amp;quot;#66FF99&amp;quot; | [[it07:Capreomycin|Capreomycin (Drug-resistant TB)]]&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
== Supplemental  Project Page ==&lt;br /&gt;
&lt;br /&gt;
This area is for people who wish to create their own projects if none of the above appeal to them. Click on the  &#039;&#039;&#039;Edit&#039;&#039;&#039;  button to the right to open up an editable page,&lt;br /&gt;
then add an entry below as follows&lt;br /&gt;
&lt;br /&gt;
*&amp;lt;nowiki&amp;gt; [[it07:name_of_project|Descriptive name of intended project]]&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
*This will produce the effect:  [[it07:name_of_project|Descriptive name of intended project]]&lt;br /&gt;
----&lt;br /&gt;
#[[it07:sitagliptin_page|An example entry- in edit mode, please copy this line and paste below to add to this list]]&lt;br /&gt;
#[[it07:name_of_project|Vitamin C ]]&lt;br /&gt;
#[[it07:Cylcophosphamide|Cyclophosphamide]]&lt;br /&gt;
#[[it07:Terbutaline Sulphate|Terbutaline Sulphate]]&lt;br /&gt;
#[[it07:Caffeine|Caffeine]]&lt;br /&gt;
#[[it07:Mefloquine|Mefloquine]]&lt;br /&gt;
#[[it07:Cadaverine|Cadaverine]]&lt;br /&gt;
#[[it07:Cyanidin|Cyanidin]]&lt;br /&gt;
#[[it07:Ezetimibe|Ezetimibe]]&lt;br /&gt;
#[[it07:Octanitrocubane|Octanitrocubane]]&lt;br /&gt;
#[[it07:Azadirachtin|Azadirachtin]]&lt;br /&gt;
#[[it07:Nicotine|Nicotine]]&lt;br /&gt;
#[[Image:chem.png]][[it07:Cyclopentasiloxane|Cyclopentasiloxane]]&lt;br /&gt;
#[[it07:Trinitrotoluene|Trinitrotoluene]]&lt;br /&gt;
#[[it07:Hydroxychloroquine|Hydroxychloroquine]]&lt;br /&gt;
#[[it07:Aspartame|Aspartame]]&lt;br /&gt;
#[[it07:Azulene|Azulene]]&lt;br /&gt;
#[[it07:Chlorine Trifluoride|Chlorine Trifluoride]]&lt;br /&gt;
#[[it07:Cholesterol|Cholesterol]]&lt;br /&gt;
#[[it07:Vitamin E|Vitamin E]]&lt;br /&gt;
#[[it07:Phenothiazine|Phenothiazine]]&lt;br /&gt;
#[[it07:linalool|linalool]]&lt;br /&gt;
#[[it07:Glutamic acid|Glutamic acid]]&lt;br /&gt;
#[[it07:N-(4-hydroxyphenyl)ethanamide|N-(4-hydroxyphenyl)ethanamide]]&lt;br /&gt;
#[[it07:Epinephrine|Epinephrine]]&lt;br /&gt;
#[[it07:Sodium Valproate|Sodium Valproate]]&lt;br /&gt;
#[[it07:Hyaluronic acid |Hyaluronic acid  ]]&lt;br /&gt;
#[[it07:Methylenedioxymethamphetamine |Methylenedioxymethamphetamine ]]&lt;br /&gt;
#[[it07:salicylic acid |salicylic acid ]]&lt;br /&gt;
#[[it07:Morphine|Morphine]]&lt;br /&gt;
#[[Cetirizine]]&lt;br /&gt;
#[[it07:Bisacodyl|Bisacodyl]]&lt;br /&gt;
#[[it07:Rivaroxaban|Rivaroxaban]]&lt;br /&gt;
#[[it07:Sodium Lauryl Sulfate|Sodium Lauryl Sulfate]]&lt;br /&gt;
#[[it07:Silicon Dioxide|Silicon Dioxide]]&lt;br /&gt;
#[[it07:Vanillin|Vanillin]]&lt;br /&gt;
#[[it07:Tetrahydrocannabinol|Tetrahydrocannabinol]]&lt;br /&gt;
#[[it07:Capsaicin|Capsaicin]]&lt;br /&gt;
#[[it07:Menthol|Menthol]]&lt;br /&gt;
#[[it07:Tamoxifen|Tamoxifen]]&lt;br /&gt;
#[[it07:Copper arsenate|Scheele&#039;s Green]]&lt;br /&gt;
#[[it07:Strychnine|Strychnine]]&lt;br /&gt;
#[[it07:Testosterone|Testosterone]]&lt;br /&gt;
#[[it07:Monosodium glutamate|Monosodium glutamate]]&lt;br /&gt;
#[[it07:Taurine|Taurine]]&lt;br /&gt;
#[[it07:Phenethylamine|Phenethylamine]]&lt;br /&gt;
#[[it07:Verbenone|Verbenone]]&lt;br /&gt;
#[[it07:Salbutamol|Salbutamol]]&lt;br /&gt;
&lt;br /&gt;
== Cetirizine ==&lt;br /&gt;
Utilities have been written to help the conversion of material from HTML.&lt;br /&gt;
# [http://diberri.dyndns.org/wikipedia/html2wiki/ A HTML2Wiki Converter]&lt;br /&gt;
----&lt;br /&gt;
&lt;br /&gt;
== Wiki Templates ==&lt;br /&gt;
&lt;br /&gt;
[[Template:DOI]] and [[Template:Doi-inline]] are providea as (protected) templates for your use. Many other templates exist, often to be found on e.g. Wikipedia pages. You may decide one of these is of particular use, or of interest. If so, you can install it on the wiki here for you and others to use. Add below a line that looks like Template:Template-name, save, and click on the red text to create the new template. If you prefer the task of adding useful templates to that of adding information about molecules, then you will be given full credit for performing this valuable service for others! --Rzepa 14:41, 20 October 2006 (BST) &lt;br /&gt;
&lt;br /&gt;
[[Template:Chem-Data]]&lt;br /&gt;
&lt;br /&gt;
[[Template:Drug-Box]] - For pharmaceutical drugs just copy variable names and code generates tables&lt;br /&gt;
&lt;br /&gt;
[[Template:Chembox supplement]] - to be linked to from the supplementary section of the table in the template above, for usage see [[Template_talk:chembox_supplement|here]]&lt;br /&gt;
&lt;br /&gt;
[[Template:NFPA_704]] - for notes on how to use, see [[Template_talk:NFPA_704|here]]&lt;br /&gt;
&lt;br /&gt;
[[R &amp;amp; S Phrases]]&lt;br /&gt;
&lt;br /&gt;
[[Template:Chembox new]]&lt;/div&gt;</summary>
		<author><name>Whc06</name></author>
	</entry>
</feed>