ChemWiki - User contributions [en]

It:Roaccutane

2006-10-23T13:52:05Z

Jhss05:

<jmol>
<jmolApplet>
<size>500</size>
<color>white</color>
<script>zoom 100; cpk off;frame 1; move 40 -20 20 0 0 0 0 0 3; delay 1;</script>
<inlineContents>test.pdb
title1
title2
ATOM 1 C1 MOL 1 14.263 13.508 0.005 1.00 0.00
ATOM 2 C2 MOL 1 15.445 12.906 0.072 1.00 0.00
ATOM 3 C3 MOL 1 12.940 12.770 -0.027 1.00 0.00
ATOM 4 C4 MOL 1 16.692 13.626 0.034 1.00 0.00
ATOM 5 C5 MOL 1 12.825 11.196 -0.135 1.00 0.00
ATOM 6 C6 MOL 1 11.833 13.525 0.052 1.00 0.00
ATOM 7 C7 MOL 1 17.817 12.921 0.063 1.00 0.00
ATOM 8 C8 MOL 1 16.708 15.125 -0.058 1.00 0.00
ATOM 9 C9 MOL 1 13.847 10.514 -1.092 1.00 0.00
ATOM 10 C10 MOL 1 13.053 10.611 1.285 1.00 0.00
ATOM 11 C11 MOL 1 11.426 10.791 -0.613 1.00 0.00
ATOM 12 C12 MOL 1 11.973 15.022 0.150 1.00 0.00
ATOM 13 C13 MOL 1 10.425 12.944 0.039 1.00 0.00
ATOM 14 C14 MOL 1 19.122 13.553 0.008 1.00 0.00
ATOM 15 C15 MOL 1 10.413 11.431 0.300 1.00 0.00
ATOM 16 C16 MOL 1 20.200 12.776 0.050 1.00 0.00
ATOM 17 C17 MOL 1 21.537 13.348 -0.007 1.00 0.00
ATOM 18 C18 MOL 1 22.581 12.508 0.048 1.00 0.00
ATOM 19 C19 MOL 1 21.682 14.844 -0.126 1.00 0.00
ATOM 20 C20 MOL 1 24.024 12.882 0.002 1.00 0.00
ATOM 21 O21 MOL 1 24.869 11.984 0.071 1.00 0.00
ATOM 22 O22 MOL 1 24.460 14.200 -0.117 1.00 0.00
TER</inlineContents>
</jmolApplet>
</jmol>
'''Roaccutane 3-D'''
[[Image:Roaccutane.gif|thumb|right|200|Roaccutane]]

'''Roaccutane''' otherwise known as ''isoretinoin'', ''Tasmar'' or ''Teriosal''.
{| border="1"
|+
{| border="1"
! Formula !! Molecular weight !! Melting Point
|-
! C<sub>20</sub>H<sub>28</sub>O<sub>2</sub>
| 300.44 || 189-190C
|-
|}
===Interesting Fact===
'''Roaccutane''' is a form of Vitamin A prescribed by dermatologists for severe '''acne''', and it is only given to patients who have not responded to previous milder treatments. Roaccutane makes the sebaceous gland less productive, reduces the size of the sebaceous glands and the inflammation of the skin in acne.

==='''How does it work?'''===

Roaccutane ,isotretinoin, belongs to a group of medicines known as retinoids (a derivatives vitamin A),and has IUPAC name of 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid.
Roaccutane taken into body through the mouth in tablet form. This medicine works by reducing the production of the skin’s natural oil (sebum) by decreacing the size and activity of the sebaceous glands in the skin, thus stops the glands from becoming blocked and infected by bacteria.

===KIMCHI===

Roaccutane contains the active ingredient isotretinoin. This is a vitamin A derivative. Roaccutane is used to treat severe forms of acne (such as nodular orconglobate acne, or acne at risk of permanent scarring) which has not got better after other anti-acnetreatments, including oral antibiotics. Roaccutane treatment must be supervised by a dermatologist (a doctor specialised in the treatment of skin problems). Roaccutane may increase the levels of fats such as triglycerides or cholesterol in your blood. Roaccutane is teratogenic. This means that it is likely to damage an unborn baby. There is also an increased risk of miscarriage

It:Roaccutane

2006-10-23T13:51:13Z

Jhss05: /* KIMCHI */

<jmol>
<jmolApplet>
<size>500</size>
<color>white</color>
<script>zoom 100; cpk off;frame 1; move 40 -20 20 0 0 0 0 0 3; delay 1;</script>
<inlineContents>test.pdb
title1
title2
ATOM 1 C1 MOL 1 14.263 13.508 0.005 1.00 0.00
ATOM 2 C2 MOL 1 15.445 12.906 0.072 1.00 0.00
ATOM 3 C3 MOL 1 12.940 12.770 -0.027 1.00 0.00
ATOM 4 C4 MOL 1 16.692 13.626 0.034 1.00 0.00
ATOM 5 C5 MOL 1 12.825 11.196 -0.135 1.00 0.00
ATOM 6 C6 MOL 1 11.833 13.525 0.052 1.00 0.00
ATOM 7 C7 MOL 1 17.817 12.921 0.063 1.00 0.00
ATOM 8 C8 MOL 1 16.708 15.125 -0.058 1.00 0.00
ATOM 9 C9 MOL 1 13.847 10.514 -1.092 1.00 0.00
ATOM 10 C10 MOL 1 13.053 10.611 1.285 1.00 0.00
ATOM 11 C11 MOL 1 11.426 10.791 -0.613 1.00 0.00
ATOM 12 C12 MOL 1 11.973 15.022 0.150 1.00 0.00
ATOM 13 C13 MOL 1 10.425 12.944 0.039 1.00 0.00
ATOM 14 C14 MOL 1 19.122 13.553 0.008 1.00 0.00
ATOM 15 C15 MOL 1 10.413 11.431 0.300 1.00 0.00
ATOM 16 C16 MOL 1 20.200 12.776 0.050 1.00 0.00
ATOM 17 C17 MOL 1 21.537 13.348 -0.007 1.00 0.00
ATOM 18 C18 MOL 1 22.581 12.508 0.048 1.00 0.00
ATOM 19 C19 MOL 1 21.682 14.844 -0.126 1.00 0.00
ATOM 20 C20 MOL 1 24.024 12.882 0.002 1.00 0.00
ATOM 21 O21 MOL 1 24.869 11.984 0.071 1.00 0.00
ATOM 22 O22 MOL 1 24.460 14.200 -0.117 1.00 0.00
TER</inlineContents>
</jmolApplet>
</jmol>
'''Roaccutane 3-D'''
[[Image:Roaccutane.gif|thumb|right|200|Roaccutane]]

'''Roaccutane''' otherwise known as ''isoretinoin'', ''Tasmar'' or ''Teriosal''.
{| border="1"
|+
{| border="1"
! Formula !! Molecular weight !! Melting Point
|-
! C<sub>20</sub>H<sub>28</sub>O<sub>2</sub>
| 300.44 || 189-190C
|-
|}
===Interesting Fact===
'''Roaccutane''' is a form of Vitamin A prescribed by dermatologists for severe '''acne''', and it is only given to patients who have not responded to previous milder treatments. Roaccutane makes the sebaceous gland less productive, reduces the size of the sebaceous glands and the inflammation of the skin in acne.

==='''How does it work?'''===

Roaccutane ,isotretinoin, belongs to a group of medicines known as retinoids (a derivatives vitamin A),and has IUPAC name of 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid.
Roaccutane taken into body through the mouth in tablet form. This medicine works by reducing the production of the skin’s natural oil (sebum) by decreacing the size and activity of the sebaceous glands in the skin, thus stops the glands from becoming blocked and infected by bacteria.

===KIMCHI===
Roaccutane contains the active ingredient isotretinoin. This is a vitamin A derivative. Roaccutane is used to treat severe forms of acne (such as nodular orconglobate acne, or acne at risk of permanent scarring) which has not got better after other anti-acnetreatments, including oral antibiotics. Roaccutane treatment must be supervised by a dermatologist (a doctor specialised in the treatment of skin problems). Roaccutane may increase the levels of fats such as triglycerides or cholesterol in your blood. Roaccutane is teratogenic. This means that it is likely to damage an unborn baby. There is also an increased risk of miscarriage

It:Roaccutane

2006-10-23T13:36:51Z

Jhss05: