ChemWiki - User contributions [en]

It:projects

2006-10-27T10:06:25Z

Fjs05: /* Supplemental Project Page */

__FORCETOC__

'''''You MUST use the Edit buttons on the right to edit this content. Do NOT use the Edit button on the top of this page.'''''
== Sandbox (Play-Pen) ==

This is an area where you can play without worrying what you do. Enter it by pressing the [Edit] button '''on the right''' and '''not''' at the top. Go here for a [http://en.wikipedia.org/wiki/Wikipedia:Cheatsheet ''cheat sheet''] summary of how to create a Wiki page. It's a free-for-all in here! Learn how to use a Wiki by coming here! PS This is how to do Greek: Α, α, β Δ, δ
Try copying/pasting some of the [http://www.ch.ic.ac.uk/local/it/lab1.html examples in the course work] into this page. See the effect by selecting '''Show Preview'''. No not use '''Save Page''' so as to leave this area uncluttered for others.
----
<div align="left"> 

== Main Project Page ==
'''Please do not edit this page itself'''. Click on one of the titles to start editing.
{| summary="CIT Project Titles" border="1"
! bgcolor="cyan" |Project Number
! bgcolor="cyan" |General Keywords
|-
| bgcolor="#CCFF00" |01
| bgcolor="#CCFF00" | [[it:Lignocaine|Lignocaine (used in dentistry as a "local")]]
|-
| bgcolor="#CCFF00" |02
| bgcolor="#66FF99" | [[it:Piperine|Piperine (active ingredient of both black and white pepper)]]
|-
| bgcolor="#CCFF00" |03
| bgcolor="#CCFF00" | [[it:Rapamycin|Rapamycin (prevents transplant rejection)]]
|-
| bgcolor="#CCFF00" |04
| bgcolor="#66FF99" | [[it:Gossypol|Gossypol (male birth control)]]
|-
| bgcolor="#CCFF00" |05
| bgcolor="#CCFF00" | [[it:Gentamycin|Gentamicin A (aminoglycoside antibiotic)]]
|-
| bgcolor="#CCFF00" |06
| bgcolor="#66FF99" | [[it:Herceptin|Herceptin (topical anticancer drug)]]
|-
| bgcolor="#CCFF00" |07
| bgcolor="#CCFF00" | [[it:Gingerone|Zingerone (the characteristic smell of ginger)]]
|-
| bgcolor="#CCFF00" |08
| bgcolor="#66FF99" | [[it:Sucralose|Sucralose (non-metabolizable sweetening agent)]]
|-
| bgcolor="#CCFF00" |09
| bgcolor="#CCFF00" | [[it:Bufotoxin|Bufotoxin (active component of the toad ''Bufo vulgaris'')]]
|-
| bgcolor="#CCFF00" |10
| bgcolor="#66FF99" | [[it:Roaccutane|Roaccutane (treatment for severe acne)]]
|-
| bgcolor="#CCFF00" |11
| bgcolor="#CCFF00" | [[it:Sibutramine|Sibutramine (appetite suppresor)]]
|-
| bgcolor="#CCFF00" |12
| bgcolor="#66FF99" | [[it:Anandamide|Anandamide (the "feel-good" factor in chocolate)]]
|-
| bgcolor="#CCFF00" |13
| bgcolor="#CCFF00" | [[it:h3nbh3|Ammonia-borane: H3N-BH3 (Hydrogen storage molecule?)]]
|-
| bgcolor="#CCFF00" |14
| bgcolor="#66FF99" | [[it:Methoxsalen|Methoxsalen (Treatment of psoriasis)]]
|-
| bgcolor="#CCFF00" |15
| bgcolor="#CCFF00" | [[it:Hycocine|Hyoscine (From Mandrake and Witches Henbane, pre-med before surgery)]]
|-
| bgcolor="#CCFF00" |16
| bgcolor="#66FF99" | [[it:Capreomycin|Capreomycin (Drug-resistant TB)]]
|-
| bgcolor="#CCFF00" |17
| bgcolor="#CCFF00" | [[it:wilkinson|Wilkinson's catalyst]]
|-
| bgcolor="#CCFF00" |18
| bgcolor="#66FF99" | [[it:Jacobsen|Jacobsen's epoxidation catalyst]]
|-
| bgcolor="#CCFF00" |19
| bgcolor="#CCFF00" | [[it:Methylaluminoxane|Methylaluminoxane: MAO - hugely important ethylene polymerisation cocatalyst]]
|-
| bgcolor="#CCFF00" |20
| bgcolor="#66FF99" | [[it:Schwartz|Schwartz reagent for the hydrozirconation of alkenes and alkynes]]
|}

== Supplemental Project Page ==

This area is for people who wish to create their own projects if none of the above appeal to them. Click on the '''Edit''' button to the right to open up an editable page,
then add an entry below as follows

*<nowiki> [[it:name_of_project|Descriptive name of intended project]]</nowiki>
*This will produce the effect: [[it:name_of_project|Descriptive name of intended project]]
----
*[[it:sitagliptin_page|Sitagliptin]]
*[[it:Retinal|Retinal, molecule of sight]]
*[[it:Tamoxifen|Tamoxifen, breast cancer treatment]]
*[[it:Morphine|Morphine, painkiller]]
*[[it:Pelargonidin|Pelargonidin, colouring in nature]]
*[[it:Propanil|Propanil, weedkiller]]
*[[it:Ranitidine|Ranitidine, antiulcerative]]
*[[it:chlorphentermine|chlorphentermine, anorectic]]
*[[it:Serotonin|Serotonin, The 'HAPPY' Drug]]
*[[it:Amphidinolide T1|Amphidinolide T1]]
*[[it:Rosiglitazone|Rosiglitazone, drug that is currently used to treat diabetes.]]
*[[it:Furosemide|Furosemide]]
*[[it:Tryptophan|Tryptophan]]
*[[it:methylpentynol|methylpentynol, tranquilliser.]]

== [[Special:Export|Export Pages]] ==

This takes you to an '''Export''' page. A backup of the Projects area can be made (in XML) if you want to keep your own
''snapshot'' of the project pages at any instant. After you Export the page you want (ie '''It:projects''' or '''It:Lignocaine''' for example) the XML encoding of it will appear in your browser Window. You should '''view source''' for this material, copy it to a text editor, and thence save it to disk.

== Overlaps ==

If two people start editing a page at the same time, and '''save''' the change simultaneously, its possible only one of the changes
will be made permanent. If anyone spots this happening, please let me know.

One precaution you could take is to keep a copy of the contents of the page you are editing in eg Wordpad (or Word),
make the changes there, and then copy the entire lot to the Wiki page to preview and then save. Tht way, if your contribution
is overlapped by someone else, you will still have a copy, and you can then resubmit it.
----
--[[User:Rzepa|Rzepa]] 12:25, 19 October 2006 (BST)

== Wiki Utillities ==
Utilities have been written to help the conversion of material from HTML.

# [http://diberri.dyndns.org/wikipedia/html2wiki/ A HTML2Wiki Converter]

No wiki2html converter suitable for use has yet been identified.
=== Wiki Templates ===

[[Template:DOI]] and [[Template:Doi-inline]] are providea as (protected) templates for your use. Many other templates exist, often to be found on e.g. Wikipedia pages. You may decide one of these is of particular use, or of interest. If so, you can install it on the wiki here for you and others to use. Add below a line that looks like {{template-name|parameter}}, save, and click on the red text to create the new template. If you prefer the task of adding useful templates to that of adding information about molecules, then you will be given full credit for performing this valuable service for others!
--[[User:Rzepa|Rzepa]] 14:41, 20 October 2006 (BST)

----
[[Template:Chem-Data]]

It:Propanil

2006-10-27T09:59:15Z

Fjs05:

{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"
! {{chembox header}} colspan="3" |Structure of Propanil
|-
| align="center" colspan="3" bgcolor="#ffffff" | [[Image:Propanil.gif|200px{{PAGENAME}}]]
|-
! {{chembox header}} colspan="3" |3D structure
|-
| align="center" colspan="3" bgcolor="#ffffff" | <jmol>
<jmolApplet>
<size>250</size>
<color>black</color>
<script>zoom 120; cpk off;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;</script>
<inlineContents>water.mol
HEADER NONAME 23-Oct-06 NONE 1
TITLE NONE 2
AUTHOR WWW daemon apache NONE 3
REVDAT 1 23-Oct-06 0 NONE 4
ATOM 1 Cl 0 -1.937 2.063 0.234 0.00 0.00 Cl+0
ATOM 2 C 0 -1.218 0.484 0.165 0.00 0.00 C+0
ATOM 3 C 0 0.144 0.337 0.344 0.00 0.00 C+0
ATOM 4 C 0 0.718 -0.926 0.288 0.00 0.00 C+0
ATOM 5 N 0 2.097 -1.078 0.470 0.00 0.00 N+0
ATOM 6 C 0 2.948 -0.158 -0.027 0.00 0.00 C+0
ATOM 7 C 0 4.421 -0.253 0.274 0.00 0.00 C+0
ATOM 8 C 0 5.156 0.905 -0.404 0.00 0.00 C+0
ATOM 9 O 0 2.527 0.747 -0.717 0.00 0.00 O+0
ATOM 10 C 0 -0.079 -2.039 0.053 0.00 0.00 C+0
ATOM 11 C 0 -1.441 -1.887 -0.125 0.00 0.00 C+0
ATOM 12 C 0 -2.012 -0.628 -0.064 0.00 0.00 C+0
ATOM 13 Cl 0 -3.723 -0.441 -0.288 0.00 0.00 Cl+0
ATOM 14 H 0 0.762 1.204 0.526 0.00 0.00 H+0
ATOM 15 H 0 2.442 -1.846 0.953 0.00 0.00 H+0
ATOM 16 H 0 4.576 -0.200 1.352 0.00 0.00 H+0
ATOM 17 H 0 4.809 -1.200 -0.102 0.00 0.00 H+0
ATOM 18 H 0 6.222 0.836 -0.186 0.00 0.00 H+0
ATOM 19 H 0 5.002 0.851 -1.482 0.00 0.00 H+0
ATOM 20 H 0 4.769 1.851 -0.028 0.00 0.00 H+0
ATOM 21 H 0 0.365 -3.022 0.009 0.00 0.00 H+0
ATOM 22 H 0 -2.061 -2.752 -0.308 0.00 0.00 H+0
CONECT 1 2 0 0 0 NONE 27
CONECT 2 1 12 3 0 NONE 28
CONECT 3 2 4 14 0 NONE 29
CONECT 4 3 5 10 0 NONE 30
CONECT 5 4 6 15 0 NONE 31
CONECT 6 5 7 9 0 NONE 32
CONECT 7 6 8 16 17 NONE 33
CONECT 8 7 18 19 20 NONE 34
CONECT 9 6 0 0 0 NONE 35
CONECT 10 4 11 21 0 NONE 36
CONECT 11 10 12 22 0 NONE 37
CONECT 12 11 2 13 0 NONE 38
CONECT 13 12 0 0 0 NONE 39
END NONE 40
</inlineContents>
</jmolApplet>
</jmol>
|-
| align="center" colspan="3" bgcolor="#ffffff" |
|-
| [[CA Index Name]]
| colspan="2"| Propanil,
3,4-dichloropropionalide
|-
| [[Commercial Names]]
|colspan="2"| Bay 30130
Cekupropanil

Dropaven

Surcopur
|-
| [[Chemical formula|Molecular formula]]
| colspan="2" | C9H9Cl2NO
|-
| [[SMILES]]
| colspan="2" | ClC1=CC=C(NC(CC)=O)C=C1Cl
|-
| [[Molar mass]]
| colspan="2" |218.08 g/mol
|-
| [[CAS registry number|CAS number]]
| colspan="2" | 709-98-8
|-
| [[Appearance]]
| colspan="2" | white to brown crystalline solid
|-
| [[Odour]]
| colspan="2" | mildly offensive
|-
! {{chembox header}} colspan="3"| Properties
|-
| [[Density]] and [[Phase]]
| colspan="2" | 1.054g/cm3, solid
|-
| [[Solubility]] in [[Water_(molecule)|water]]
| colspan="2" | 225 ppm at 25°C
|-
| [[Melting point]]
| colspan="2" | 91-93 °C
|-
| [[Flash Point]]
| colspan="2" | 100.0°C
|-
| [[Vapor Pressure]]
| colspan="2" | 2.6x10-7 mbar
|-
| {{chembox header}} colspan="3"| Except where noted otherwise, data are given for materials in their [[standard state|standard state (at 25 °C, 100 kPa)]] [[wikipedia:Chemical infobox|Infobox disclaimer and references]]
|-
|}

==What is Propanil?==
Propanil is an anilide used as a herbicide in a number of economically important crops, such as rice, potato and corn, against broad-leaved and grass weeds. It is sold as emulsifiable concentrates, liquid and dry flowable, low volume and ultra low volume formulations. Early weed control removes competition, conserves moisture and contributes to increased yields. Propanil formulations may be used on dry planted, hydroponic, or transplanted crops.

==Synthesis==
[[Image:Reaction_Mech_Propanil.gif|200px{{PAGENAME}}]]

==Spectra==
Below are spectra of propanil. The first is an IR spectrum of propanil in its gas phase. The second is a mass spectrum of propanil. You can clearly see the parent molecular ion peak is positioned close to the recorded molecular mass of propanil - 218.08amu. There are two chlorine atoms in this compound, and peaks due to the different isotopes of chlorine, namely Cl35 and Cl37, are responsible for the lack of a clear single parent molecular ion peak. The recorded molecular mass of propanil takes into the account the differing masses of the 2 isotopes of chlorine and their relative proportions (approximately 75% 35Cl and 25% 37Cl).

[[Image:Propanil_IR_Spectrum.gif|thumb|left|75|IR Spectrum of Propanil]]
[[Image:Propanil_mass_Spectrum.gif|thumb|left|75|IR Spectrum of Propanil]]

==References==
* Stuart Warren, Organic Synthesis - The Disconnection Approach, pp27-28
* http://www.propanil.com/
* [http://pmep.cce.cornell.edu/profiles/extoxnet/metiram-propoxur/propanil-ext.html#4 Extoxnet Page]
* [http://pubs.acs.org/cgi-bin/article.cgi/jafcau/2003/51/i04/html/jf025957v.html/QueryZIP/C3-I/((((VOL@@%3CMATCHES%3E@@51)))%3CAND%3E((SPN@@%3CMATCHES%3E@@876)))%3CAND%3E(%3CANY%3E(JAFCAU)%3CIN%3ECDN) Electrochemical and Spectroscopic Studies of the Oxidation Mechanism of the Herbicide Propanil]
* NIST Mass Spec Data Center, S.E. Stein, director

It:Ranitidine

2006-10-24T16:53:02Z

Fjs05:

{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"
! {{chembox header}} colspan="3" |Structure of Ranitidine
|-
| align="center" colspan="3" bgcolor="#ffffff" | [[Image:Ranitidine.gif|200px{{PAGENAME}}]]
|-
! {{chembox header}} colspan="3" |3D structure
|-
| align="center" colspan="3" bgcolor="#ffffff" | <jmol>
<jmolApplet>
<size>250</size>
<color>black</color>
<script>zoom 120; cpk off;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;</script>
<inlineContents>Ranitidine.mol
HEADER NONAME 24-Oct-06 NONE 1
TITLE NONE 2
AUTHOR WWW daemon apache NONE 3
REVDAT 1 24-Oct-06 0 NONE 4
ATOM 1 C 0 8.067 -1.506 -1.248 0.00 0.00 C+0
ATOM 2 N 0 7.095 -0.912 -0.321 0.00 0.00 N+0
ATOM 3 C 0 7.827 0.075 0.484 0.00 0.00 C+0
ATOM 4 C 0 6.135 -0.160 -1.140 0.00 0.00 C+0
ATOM 5 C 0 4.972 0.271 -0.284 0.00 0.00 C+0
ATOM 6 C 0 4.887 1.424 0.404 0.00 0.00 C+0
ATOM 7 C 0 3.636 1.416 1.063 0.00 0.00 C+0
ATOM 8 C 0 3.032 0.259 0.738 0.00 0.00 C+0
ATOM 9 C 0 1.672 -0.188 1.210 0.00 0.00 C+0
ATOM 10 S 0 0.408 0.388 0.043 0.00 0.00 S+0
ATOM 11 C 0 -1.081 -0.275 0.839 0.00 0.00 C+0
ATOM 12 C 0 -2.311 0.097 0.009 0.00 0.00 C+0
ATOM 13 N 0 -3.514 -0.438 0.652 0.00 0.00 N+0
ATOM 14 C 0 -4.762 -0.226 0.078 0.00 0.00 C+0
ATOM 15 N 0 -4.868 0.493 -1.107 0.00 0.00 N+0
ATOM 16 C 0 -5.137 1.932 -1.068 0.00 0.00 C+0
ATOM 17 C 0 -5.854 -0.712 0.662 0.00 0.00 C+0
ATOM 18 N 0 -7.167 -0.601 -0.014 0.00 0.00 N+1
ATOM 19 O 0 -7.261 0.006 -1.066 0.00 0.00 O-1
ATOM 20 O 0 -8.153 -1.116 0.482 0.00 0.00 O+0
ATOM 21 O 0 3.844 -0.428 -0.082 0.00 0.00 O+0
ATOM 22 H 0 8.805 -2.077 -0.684 0.00 0.00 H+0
ATOM 23 H 0 7.550 -2.167 -1.943 0.00 0.00 H+0
ATOM 24 H 0 8.569 -0.714 -1.804 0.00 0.00 H+0
ATOM 25 H 0 7.144 0.546 1.191 0.00 0.00 H+0
ATOM 26 H 0 8.628 -0.423 1.029 0.00 0.00 H+0
ATOM 27 H 0 8.251 0.835 -0.172 0.00 0.00 H+0
ATOM 28 H 0 6.624 0.719 -1.558 0.00 0.00 H+0
ATOM 29 H 0 5.774 -0.794 -1.950 0.00 0.00 H+0
ATOM 30 H 0 5.631 2.205 0.445 0.00 0.00 H+0
ATOM 31 H 0 3.241 2.190 1.704 0.00 0.00 H+0
ATOM 32 H 0 1.646 -1.276 1.266 0.00 0.00 H+0
ATOM 33 H 0 1.474 0.231 2.196 0.00 0.00 H+0
ATOM 34 H 0 -1.004 -1.360 0.909 0.00 0.00 H+0
ATOM 35 H 0 -1.176 0.148 1.839 0.00 0.00 H+0
ATOM 36 H 0 -2.388 1.182 -0.061 0.00 0.00 H+0
ATOM 37 H 0 -2.216 -0.326 -0.991 0.00 0.00 H+0
ATOM 38 H 0 -3.440 -0.939 1.479 0.00 0.00 H+0
ATOM 39 H 0 -4.765 0.041 -1.959 0.00 0.00 H+0
ATOM 40 H 0 -6.040 2.118 -0.487 0.00 0.00 H+0
ATOM 41 H 0 -4.295 2.447 -0.605 0.00 0.00 H+0
ATOM 42 H 0 -5.276 2.303 -2.084 0.00 0.00 H+0
ATOM 43 H 0 -5.783 -1.187 1.630 0.00 0.00 H+0
CONECT 1 2 22 23 24 NONE 48
CONECT 2 1 3 4 0 NONE 49
CONECT 3 2 25 26 27 NONE 50
CONECT 4 2 5 28 29 NONE 51
CONECT 5 4 21 6 0 NONE 52
CONECT 6 5 7 30 0 NONE 53
CONECT 7 6 8 31 0 NONE 54
CONECT 8 7 9 21 0 NONE 55
CONECT 9 8 10 32 33 NONE 56
CONECT 10 9 11 0 0 NONE 57
CONECT 11 10 12 34 35 NONE 58
CONECT 12 11 13 36 37 NONE 59
CONECT 13 12 14 38 0 NONE 60
CONECT 14 13 15 17 0 NONE 61
CONECT 15 14 16 39 0 NONE 62
CONECT 16 15 40 41 42 NONE 63
CONECT 17 14 18 43 0 NONE 64
CONECT 18 17 19 20 0 NONE 65
CONECT 19 18 0 0 0 NONE 66
CONECT 20 18 0 0 0 NONE 67
CONECT 21 8 5 0 0 NONE 68
END NONE 69
</inlineContents>
</jmolApplet>
</jmol>
|-
| align="center" colspan="3" bgcolor="#ffffff" |
|-
| [[CA Index Name]]
| colspan="2"| Ranitidine,
(E)-N-(2-((5-((dimethylaminomethyl)furan-2-yl) 
methylthio)ethyl)-N'-methyl-2-nitroethene-1,1-diamine
|-
| [[Commercial Name]]
|colspan="2"| Zantac (GSK)
|-
| [[Chemical formula|Molecular formula]]
| colspan="2" | C13H22N4O3S
|-
| [[SMILES]]
| colspan="2" | CN(C)CC1=CC=C(CSCCN/C(NC)=C/[N+]([O-])=O)O1
|-
| [[Molar mass]]
| colspan="2" |314.41 g/mol
|-
| [[CAS registry number|CAS number]]
| colspan="2" | 66357-59-3
|-
| [[Appearance]]
| colspan="2" | tan coloured solid
|-
! {{chembox header}} colspan="3"| Properties
|-
| [[Phase]]
| colspan="2" | solid
|-
| [[Solubility]] in [[Water_(molecule)|water]]
| colspan="2" | 24.7 mg/mL at 25°C
|-
| [[LogP/Hydrophobicity]]
| colspan="2" | 1.93
|-
| [[Melting point]]
| colspan="2" | 69-70°C
|-
| {{chembox header}} colspan="3"| Except where noted otherwise, data are given for materials in their [[standard state|standard state (at 25 °C, 100 kPa)]] [[wikipedia:Chemical infobox|Infobox disclaimer and references]]
|-
|}
==What is Ranitidine?==
Ranitidine is in a class of drugs known as H2 receptor antagonists. It is used to treat conditions such as reflux oesophagitis and ulcers of the stomach and intestine, which are caused by too much acid being produced in the stomach. Ranitidine is available as a tablet, effervescent tablet, oral liquid and injection form.

==Possible Side Effects==
There are some minor side effects which can be caused by Ranitidine use:
*Diarrhoea
*Headaches
*Dizziness
*Skin rashes
*Fatigue
*Unusual aches and pains or fever
 
Serious side effects are not common with this medication, but the following have been noted in some patients:
*Allergic reaction
*Easy or unusual bruising or bleeding
*Bleeding gums
*Irregular heartbeat
*Yellowing of the skin or eyes

==References==
*[http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD00254 DrugBank (Ranitidine)]
*http://www.patient.co.uk/showdoc/30003823/
*[http://health.yahoo.com/drug/d00021a1#d00021a1-whatis Yahoo Drug Guide (Ranitidine)]

It:projects

2006-10-24T16:46:44Z

Fjs05: /* Supplemental Project Page */

__FORCETOC__

'''''You MUST use the Edit buttons on the right to edit this content. Do NOT use the Edit button on the top of this page.'''''
== Sandbox (Play-Pen) ==

This is an area where you can play without worrying what you do. Enter it by pressing the [Edit] button '''on the right''' and '''not''' at the top. Go here for a [http://en.wikipedia.org/wiki/Wikipedia:Cheatsheet ''cheat sheet''] summary of how to create a Wiki page. It's a free-for-all in here! Learn how to use a Wiki by coming here! PS This is how to do Greek: Α, α, β Δ, δ
Try copying/pasting some of the [http://www.ch.ic.ac.uk/local/it/lab1.html examples in the course work] into this page. See the effect by selecting '''Show Preview'''. No not use '''Save Page''' so as to leave this area uncluttered for others.
----
<div align="left"> 

== Main Project Page ==
'''Please do not edit this page itself'''. Click on one of the titles to start editing.
{| summary="CIT Project Titles" border="1"
! bgcolor="cyan" |Project Number
! bgcolor="cyan" |General Keywords
|-
| bgcolor="#CCFF00" |01
| bgcolor="#CCFF00" | [[it:Lignocaine|Lignocaine (used in dentistry as a "local")]]
|-
| bgcolor="#CCFF00" |02
| bgcolor="#66FF99" | [[it:Piperine|Piperine (active ingredient of both black and white pepper)]]
|-
| bgcolor="#CCFF00" |03
| bgcolor="#CCFF00" | [[it:Rapamycin|Rapamycin (prevents transplant rejection)]]
|-
| bgcolor="#CCFF00" |04
| bgcolor="#66FF99" | [[it:Gossypol|Gossypol (male birth control)]]
|-
| bgcolor="#CCFF00" |05
| bgcolor="#CCFF00" | [[it:Gentamycin|Gentamicin A (aminoglycoside antibiotic)]]
|-
| bgcolor="#CCFF00" |06
| bgcolor="#66FF99" | [[it:Herceptin|Herceptin (topical anticancer drug)]]
|-
| bgcolor="#CCFF00" |07
| bgcolor="#CCFF00" | [[it:Gingerone|Zingerone (the characteristic smell of ginger)]]
|-
| bgcolor="#CCFF00" |08
| bgcolor="#66FF99" | [[it:Sucralose|Sucralose (non-metabolizable sweetening agent)]]
|-
| bgcolor="#CCFF00" |09
| bgcolor="#CCFF00" | [[it:Bufotoxin|Bufotoxin (active component of the toad ''Bufo vulgaris'')]]
|-
| bgcolor="#CCFF00" |10
| bgcolor="#66FF99" | [[it:Roaccutane|Roaccutane (treatment for severe acne)]]
|-
| bgcolor="#CCFF00" |11
| bgcolor="#CCFF00" | [[it:Sibutramine|Sibutramine (appetite suppresor)]]
|-
| bgcolor="#CCFF00" |12
| bgcolor="#66FF99" | [[it:Anandamide|Anandamide (the "feel-good" factor in chocolate)]]
|-
| bgcolor="#CCFF00" |13
| bgcolor="#CCFF00" | [[it:h3nbh3|Ammonia-borane: H3N-BH3 (Hydrogen storage molecule?)]]
|-
| bgcolor="#CCFF00" |14
| bgcolor="#66FF99" | [[it:Methoxsalen|Methoxsalen (Treatment of psoriasis)]]
|-
| bgcolor="#CCFF00" |15
| bgcolor="#CCFF00" | [[it:Hycocine|Hyoscine (From Mandrake and Witches Henbane, pre-med before surgery)]]
|-
| bgcolor="#CCFF00" |16
| bgcolor="#66FF99" | [[it:Capreomycin|Capreomycin (Drug-resistant TB)]]
|-
| bgcolor="#CCFF00" |17
| bgcolor="#CCFF00" | [[it:wilkinson|Wilkinson's catalyst]]
|-
| bgcolor="#CCFF00" |18
| bgcolor="#66FF99" | [[it:Jacobsen|Jacobsen's epoxidation catalyst]]
|-
| bgcolor="#CCFF00" |19
| bgcolor="#CCFF00" | [[it:Methylaluminoxane|Methylaluminoxane: MAO - hugely important ethylene polymerisation cocatalyst]]
|-
| bgcolor="#CCFF00" |20
| bgcolor="#66FF99" | [[it:Schwartz|Schwartz reagent for the hydrozirconation of alkenes and alkynes]]
|}

== Supplemental Project Page ==

This area is for people who wish to create their own projects if none of the above appeal to them. Click on the '''Edit''' button to the right to open up an editable page,
then add an entry below as follows

*<nowiki> [[it:name_of_project|Descriptive name of intended project]]</nowiki>
*This will produce the effect: [[it:name_of_project|Descriptive name of intended project]]
----
*[[it:sitagliptin_page|Sitagliptin]]
*[[it:Retinal|Retinal, molecule of sight]]
*[[it:Tamoxifen|Tamoxifen, breast cancer treatment]]
*[[it:Morphine|Morphine, painkiller]]
*[[it:Pelargonidin|Pelargonidin, colouring in nature]]
*[[it:Propanil|Propanil, weedkiller]]
*[[it:Ranitidine|Ranitidine, antiulcerative]]
*[[it:chlorphentermine|chlorphentermine, anorectic]]
*[[it:Serotonin|Serotonin, The 'HAPPY' Drug]]
*[[it:Amphidinolide T1|Amphidinolide T1, potential anti-cancer drug, extracted from a Japanese Flatworm]]

== [[Special:Export|Export Pages]] ==

This takes you to an '''Export''' page. A backup of the Projects area can be made (in XML) if you want to keep your own
''snapshot'' of the project pages at any instant. After you Export the page you want (ie '''It:projects''' or '''It:Lignocaine''' for example) the XML encoding of it will appear in your browser Window. You should '''view source''' for this material, copy it to a text editor, and thence save it to disk.

== Overlaps ==

If two people start editing a page at the same time, and '''save''' the change simultaneously, its possible only one of the changes
will be made permanent. If anyone spots this happening, please let me know.

One precaution you could take is to keep a copy of the contents of the page you are editing in eg Wordpad (or Word),
make the changes there, and then copy the entire lot to the Wiki page to preview and then save. Tht way, if your contribution
is overlapped by someone else, you will still have a copy, and you can then resubmit it.
----
--[[User:Rzepa|Rzepa]] 12:25, 19 October 2006 (BST)

== Wiki Utillities ==
Utilities have been written to help the conversion of material from HTML.

# [http://diberri.dyndns.org/wikipedia/html2wiki/ A HTML2Wiki Converter]

No wiki2html converter suitable for use has yet been identified.
=== Wiki Templates ===

[[Template:DOI]] and [[Template:Doi-inline]] are providea as (protected) templates for your use. Many other templates exist, often to be found on e.g. Wikipedia pages. You may decide one of these is of particular use, or of interest. If so, you can install it on the wiki here for you and others to use. Add below a line that looks like {{template-name|parameter}}, save, and click on the red text to create the new template. If you prefer the task of adding useful templates to that of adding information about molecules, then you will be given full credit for performing this valuable service for others!
--[[User:Rzepa|Rzepa]] 14:41, 20 October 2006 (BST)

----
[[Template:Chem-Data]]

It:Ranitidine

2006-10-24T16:44:34Z

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It:Ranitidine

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{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"
! {{chembox header}} colspan="3" |Structure of Ranitidine
|-
| align="center" colspan="3" bgcolor="#ffffff" | [[Image:Ranitidine.gif|200px{{PAGENAME}}]]
|-
! {{chembox header}} colspan="3" |3D structure
|-
| align="center" colspan="3" bgcolor="#ffffff" | <jmol>
<jmolApplet>
<size>250</size>
<color>black</color>
<script>zoom 120; cpk off;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;</script>
<inlineContents>Ranitidine.mol
HEADER NONAME 24-Oct-06 NONE 1
TITLE NONE 2
AUTHOR WWW daemon apache NONE 3
REVDAT 1 24-Oct-06 0 NONE 4
ATOM 1 C 0 8.067 -1.506 -1.248 0.00 0.00 C+0
ATOM 2 N 0 7.095 -0.912 -0.321 0.00 0.00 N+0
ATOM 3 C 0 7.827 0.075 0.484 0.00 0.00 C+0
ATOM 4 C 0 6.135 -0.160 -1.140 0.00 0.00 C+0
ATOM 5 C 0 4.972 0.271 -0.284 0.00 0.00 C+0
ATOM 6 C 0 4.887 1.424 0.404 0.00 0.00 C+0
ATOM 7 C 0 3.636 1.416 1.063 0.00 0.00 C+0
ATOM 8 C 0 3.032 0.259 0.738 0.00 0.00 C+0
ATOM 9 C 0 1.672 -0.188 1.210 0.00 0.00 C+0
ATOM 10 S 0 0.408 0.388 0.043 0.00 0.00 S+0
ATOM 11 C 0 -1.081 -0.275 0.839 0.00 0.00 C+0
ATOM 12 C 0 -2.311 0.097 0.009 0.00 0.00 C+0
ATOM 13 N 0 -3.514 -0.438 0.652 0.00 0.00 N+0
ATOM 14 C 0 -4.762 -0.226 0.078 0.00 0.00 C+0
ATOM 15 N 0 -4.868 0.493 -1.107 0.00 0.00 N+0
ATOM 16 C 0 -5.137 1.932 -1.068 0.00 0.00 C+0
ATOM 17 C 0 -5.854 -0.712 0.662 0.00 0.00 C+0
ATOM 18 N 0 -7.167 -0.601 -0.014 0.00 0.00 N+1
ATOM 19 O 0 -7.261 0.006 -1.066 0.00 0.00 O-1
ATOM 20 O 0 -8.153 -1.116 0.482 0.00 0.00 O+0
ATOM 21 O 0 3.844 -0.428 -0.082 0.00 0.00 O+0
ATOM 22 H 0 8.805 -2.077 -0.684 0.00 0.00 H+0
ATOM 23 H 0 7.550 -2.167 -1.943 0.00 0.00 H+0
ATOM 24 H 0 8.569 -0.714 -1.804 0.00 0.00 H+0
ATOM 25 H 0 7.144 0.546 1.191 0.00 0.00 H+0
ATOM 26 H 0 8.628 -0.423 1.029 0.00 0.00 H+0
ATOM 27 H 0 8.251 0.835 -0.172 0.00 0.00 H+0
ATOM 28 H 0 6.624 0.719 -1.558 0.00 0.00 H+0
ATOM 29 H 0 5.774 -0.794 -1.950 0.00 0.00 H+0
ATOM 30 H 0 5.631 2.205 0.445 0.00 0.00 H+0
ATOM 31 H 0 3.241 2.190 1.704 0.00 0.00 H+0
ATOM 32 H 0 1.646 -1.276 1.266 0.00 0.00 H+0
ATOM 33 H 0 1.474 0.231 2.196 0.00 0.00 H+0
ATOM 34 H 0 -1.004 -1.360 0.909 0.00 0.00 H+0
ATOM 35 H 0 -1.176 0.148 1.839 0.00 0.00 H+0
ATOM 36 H 0 -2.388 1.182 -0.061 0.00 0.00 H+0
ATOM 37 H 0 -2.216 -0.326 -0.991 0.00 0.00 H+0
ATOM 38 H 0 -3.440 -0.939 1.479 0.00 0.00 H+0
ATOM 39 H 0 -4.765 0.041 -1.959 0.00 0.00 H+0
ATOM 40 H 0 -6.040 2.118 -0.487 0.00 0.00 H+0
ATOM 41 H 0 -4.295 2.447 -0.605 0.00 0.00 H+0
ATOM 42 H 0 -5.276 2.303 -2.084 0.00 0.00 H+0
ATOM 43 H 0 -5.783 -1.187 1.630 0.00 0.00 H+0
CONECT 1 2 22 23 24 NONE 48
CONECT 2 1 3 4 0 NONE 49
CONECT 3 2 25 26 27 NONE 50
CONECT 4 2 5 28 29 NONE 51
CONECT 5 4 21 6 0 NONE 52
CONECT 6 5 7 30 0 NONE 53
CONECT 7 6 8 31 0 NONE 54
CONECT 8 7 9 21 0 NONE 55
CONECT 9 8 10 32 33 NONE 56
CONECT 10 9 11 0 0 NONE 57
CONECT 11 10 12 34 35 NONE 58
CONECT 12 11 13 36 37 NONE 59
CONECT 13 12 14 38 0 NONE 60
CONECT 14 13 15 17 0 NONE 61
CONECT 15 14 16 39 0 NONE 62
CONECT 16 15 40 41 42 NONE 63
CONECT 17 14 18 43 0 NONE 64
CONECT 18 17 19 20 0 NONE 65
CONECT 19 18 0 0 0 NONE 66
CONECT 20 18 0 0 0 NONE 67
CONECT 21 8 5 0 0 NONE 68
END NONE 69
</inlineContents>
</jmolApplet>
</jmol>
|-
| align="center" colspan="3" bgcolor="#ffffff" |
|-
| [[CA Index Name]]
| colspan="2"| Ranitidine,
(E)-N-(2-((5-((dimethylaminomethyl)furan-2-yl) 
methylthio)ethyl)-N'-methyl-2-nitroethene-1,1-diamine
|-
| [[Commercial Name]]
|colspan="2"| Zantac (GSK)
|-
| [[Chemical formula|Molecular formula]]
| colspan="2" | C13H22N4O3S
|-
| [[SMILES]]
| colspan="2" | CN(C)CC1=CC=C(CSCCN/C(NC)=C/[N+]([O-])=O)O1
|-
| [[Molar mass]]
| colspan="2" |314.41 g/mol
|-
| [[CAS registry number|CAS number]]
| colspan="2" | 66357-59-3
|-
| [[Appearance]]
| colspan="2" | tan coloured solid
|-
! {{chembox header}} colspan="3"| Properties
|-
| [[Phase]]
| colspan="2" | solid
|-
| [[Solubility]] in [[Water_(molecule)|water]]
| colspan="2" | 24.7 mg/mL at 25°C
|-
| [[LogP/Hydrophobicity]]
| colspan="2" | 1.93
|-
| [[Melting point]]
| colspan="2" | 69-70°C
|-
| {{chembox header}} colspan="3"| Except where noted otherwise, data are given for materials in their [[standard state|standard state (at 25 °C, 100 kPa)]] [[wikipedia:Chemical infobox|Infobox disclaimer and references]]
|-
|}
==What is Ranitidine?==
Ranitidine is in a class of drugs known as H2 receptor antagonists. It is used to treat conditions such as ulcers of the stomach and intestine, which are caused by too much acid being produced in the stomach.

It:Ranitidine

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It:Ranitidine

2006-10-24T15:55:28Z

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2006-10-24T13:05:36Z

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{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"
! {{chembox header}} colspan="3" |Structure of Propanil
|-
| align="center" colspan="3" bgcolor="#ffffff" | [[Image:Propanil.gif|200px{{PAGENAME}}]]
|-
! {{chembox header}} colspan="3" |3D structure
|-
| align="center" colspan="3" bgcolor="#ffffff" | <jmol>
<jmolApplet>
<size>250</size>
<color>black</color>
<script>zoom 120; cpk off;frame 1; move 10 -20 10 0 0 0 0 0 3; delay 1;</script>
<inlineContents>water.mol
HEADER NONAME 23-Oct-06 NONE 1
TITLE NONE 2
AUTHOR WWW daemon apache NONE 3
REVDAT 1 23-Oct-06 0 NONE 4
ATOM 1 Cl 0 -1.937 2.063 0.234 0.00 0.00 Cl+0
ATOM 2 C 0 -1.218 0.484 0.165 0.00 0.00 C+0
ATOM 3 C 0 0.144 0.337 0.344 0.00 0.00 C+0
ATOM 4 C 0 0.718 -0.926 0.288 0.00 0.00 C+0
ATOM 5 N 0 2.097 -1.078 0.470 0.00 0.00 N+0
ATOM 6 C 0 2.948 -0.158 -0.027 0.00 0.00 C+0
ATOM 7 C 0 4.421 -0.253 0.274 0.00 0.00 C+0
ATOM 8 C 0 5.156 0.905 -0.404 0.00 0.00 C+0
ATOM 9 O 0 2.527 0.747 -0.717 0.00 0.00 O+0
ATOM 10 C 0 -0.079 -2.039 0.053 0.00 0.00 C+0
ATOM 11 C 0 -1.441 -1.887 -0.125 0.00 0.00 C+0
ATOM 12 C 0 -2.012 -0.628 -0.064 0.00 0.00 C+0
ATOM 13 Cl 0 -3.723 -0.441 -0.288 0.00 0.00 Cl+0
ATOM 14 H 0 0.762 1.204 0.526 0.00 0.00 H+0
ATOM 15 H 0 2.442 -1.846 0.953 0.00 0.00 H+0
ATOM 16 H 0 4.576 -0.200 1.352 0.00 0.00 H+0
ATOM 17 H 0 4.809 -1.200 -0.102 0.00 0.00 H+0
ATOM 18 H 0 6.222 0.836 -0.186 0.00 0.00 H+0
ATOM 19 H 0 5.002 0.851 -1.482 0.00 0.00 H+0
ATOM 20 H 0 4.769 1.851 -0.028 0.00 0.00 H+0
ATOM 21 H 0 0.365 -3.022 0.009 0.00 0.00 H+0
ATOM 22 H 0 -2.061 -2.752 -0.308 0.00 0.00 H+0
CONECT 1 2 0 0 0 NONE 27
CONECT 2 1 12 3 0 NONE 28
CONECT 3 2 4 14 0 NONE 29
CONECT 4 3 5 10 0 NONE 30
CONECT 5 4 6 15 0 NONE 31
CONECT 6 5 7 9 0 NONE 32
CONECT 7 6 8 16 17 NONE 33
CONECT 8 7 18 19 20 NONE 34
CONECT 9 6 0 0 0 NONE 35
CONECT 10 4 11 21 0 NONE 36
CONECT 11 10 12 22 0 NONE 37
CONECT 12 11 2 13 0 NONE 38
CONECT 13 12 0 0 0 NONE 39
END NONE 40
</inlineContents>
</jmolApplet>
</jmol>
|-
| align="center" colspan="3" bgcolor="#ffffff" |
|-
| [[CA Index Name]]
| colspan="2"| Propanil,
3,4-dichloropropionalide
|-
| [[Commercial Names]]
|colspan="2"| Bay 30130
Cekupropanil

Dropaven

Surcopur
|-
| [[Chemical formula|Molecular formula]]
| colspan="2" | C9H9Cl2NO
|-
| [[SMILES]]
| colspan="2" | ClC1=CC=C(NC(CC)=O)C=C1Cl
|-
| [[Molar mass]]
| colspan="2" |218.08 g/mol
|-
| [[CAS registry number|CAS number]]
| colspan="2" | 709-98-8
|-
| [[Appearance]]
| colspan="2" | white to brown crystalline solid
|-
| [[Odour]]
| colspan="2" | mildly offensive
|-
! {{chembox header}} colspan="3"| Properties
|-
| [[Density]] and [[Phase]]
| colspan="2" | 1.054g/cm3, solid
|-
| [[Solubility]] in [[Water_(molecule)|water]]
| colspan="2" | 225 ppm at 25°C
|-
| [[Melting point]]
| colspan="2" | 91-93 °C
|-
| [[Flash Point]]
| colspan="2" | 100.0°C
|-
| [[Vapor Pressure]]
| colspan="2" | 2.6x10-7 mbar
|-
| {{chembox header}} colspan="3"| Except where noted otherwise, data are given for materials in their [[standard state|standard state (at 25 °C, 100 kPa)]] [[wikipedia:Chemical infobox|Infobox disclaimer and references]]
|-
|}

==What is Propanil?==
Propanil is an anilide used as a herbicide in a number of economically important crops, such as rice, potato and corn, against broad-leaved and grass weeds. It is sold as emulsifiable concentrates, liquid and dry flowable, low volume and ultra low volume formulations. Early weed control removes competition, conserves moisture and contributes to increased yields. Propanil formulations may be used on dry planted, hydroponic, or transplanted crops.

==Synthesis==
[[Image:Reaction_Mech_Propanil.gif|200px{{PAGENAME}}]]
 
 
 
 
 
 
 
 
 
 
 
 
 
==References==
* Stuart Warren, Organic Synthesis - The Disconnection Approach, pp27-28
* http://www.propanil.com/
* http://pmep.cce.cornell.edu/profiles/extoxnet/metiram-propoxur/propanil-ext.html#4
* [http://pubs.acs.org/cgi-bin/article.cgi/jafcau/2003/51/i04/html/jf025957v.html/QueryZIP/C3-I/((((VOL@@%3CMATCHES%3E@@51)))%3CAND%3E((SPN@@%3CMATCHES%3E@@876)))%3CAND%3E(%3CANY%3E(JAFCAU)%3CIN%3ECDN) Electrochemical and Spectroscopic Studies of the Oxidation Mechanism of the Herbicide Propanil]

It:Propanil

2006-10-24T12:56:53Z

Fjs05:

2006-10-23T14:55:04Z